Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Associate Director/Director, Program Manager, CLYM116
$195K - $255K *
Elevate program execution by translating strategic plans into actionable timelines. Collaborate across functions to ensure alignment, manage risks, and drive decisions, while leveraging AI tools for e...
1 week ago
$300K - $350K *
Champion high-quality, patient-centered care by leading clinical initiatives, enhancing performance standards, and fostering collaboration among medical staff to ensure optimal patient experiences and...
1 week ago
Director Clinical Pharmacology
$150K - $180K *
Lead clinical pharmacology strategies and drive innovative modeling to enhance drug development. Collaborate cross-functionally to integrate pharmacokinetic insights into global plans, ensuring regula...
6 days ago
Senior Director of Clinical Services
$129K - $205K *
Lead the charge in shaping clinical strategy across a vast network of dialysis clinics, driving quality outcomes and patient safety while mentoring clinical leaders and fostering collaboration with ke...
1 week ago
Senior Director of Clinical Services
$129K - $205K *
Unlock potential by leading clinical strategy across a vast network of dialysis clinics. Drive quality outcomes, enhance patient safety, and foster talent development while collaborating with executiv...
1 week ago
Group Product Manager (Clinical Trials software)
$120K - $145K *
Champion the vision and strategy for a key business portfolio, driving product outcomes and team performance while ensuring alignment with company goals and market needs. Lead a high-performing team t...
2 weeks ago
$75K - $90K *
Contribute to impactful substance abuse programs by leading clinical teams, ensuring compliance with regulations, and promoting innovative treatment approaches within a dynamic care continuum from Det...
3 weeks ago
PMHNP / Clinical Practice Operations Manager
$110K *
Join a team that's dedicated to delivering high-quality psychiatric care while enhancing practice operations. Balance direct patient care with leadership responsibilities to drive efficiency and suppo...
2 weeks ago
$159K - $211K *
Join us in transforming quality operations by leading a robust PACE quality program, ensuring compliance and care excellence while collaborating cross-functionally to enhance participant outcomes and...
2 weeks ago
Associate Director, Media Operations
$110K - $130K *
Develop and implement efficient SOPs and systems in media operations, enhance workflows, and drive resource allocation, ensuring seamless collaboration and compliance across teams while fostering a cu...
4 weeks ago
Associate Director of Ambulatory Operations
$110K - $130K *
Drive operational excellence in ambulatory practices, ensuring patient-centered care and fiscal viability. Collaborate with leadership to enhance strategic, operational, and financial performance whil...
2 weeks ago
Senior Director, Network Operations
$206K - $350K *
Pioneer strategic network operations, driving efficiency and compliance while leading a high-performance team. Oversee regulatory implementation, enhance provider experience, and ensure alignment with...
1 week ago
Sr. Director, Program Management
$123K - $166K *
Drive operational excellence by leading a team of program managers, enhancing client relationships, and ensuring high-quality deliverables while fostering a culture of continuous improvement and strat...
1 week ago
Sr. Director, Program Management
$123K - $166K *
Lead and mentor a team of program managers, driving client program success and operational excellence. Collaborate across departments to enhance processes, ensure compliance, and achieve strategic goa...
1 week ago
$180K - $220K *
Lead a dynamic team in driving integrated primary care services, enhancing patient outcomes and organizational growth through strategic leadership and innovative care models in a supportive, collabora...
1 month ago
Director/Sr. Director Clinical Pharmacology
$262K - $284K *
Optimize pediatric drug development strategies as a clinical pharmacology leader, overseeing pharmacometric analyses and regulatory submissions, while translating complex data into actionable decision...
Reposted 3 weeks ago
Hybrid Director of Client Operations - Central Florida
$100K - $120K *
Empower your career by leading client operations to enhance satisfaction and drive business growth. Collaborate with teams to manage accounts, develop new opportunities, and ensure compliance in a dyn...
Today
Hybrid Director of Client Operations - Central Florida
$100K - $120K *
Elevate client satisfaction by leading dedicated teams, managing accounts, and driving business growth. Collaborate effectively with clients and internal teams in a dynamic environment, ensuring opera...
Today
Hybrid Director of Client Operations - Central Florida
$95K - $115K *
Grow your career with a dynamic team focused on client satisfaction and operational excellence. Lead client accounts, foster relationships, and drive performance metrics while navigating a fast-paced...
Today
Outpatient Clinic Director - Gill Mental Health Clinic
$90K - $100K *
Lead the charge in enhancing mental health services at our outpatient clinic. Oversee clinical operations, ensure effective treatment delivery, and support staff to fulfill the agency's mission of emp...
3 weeks ago
BCBA Associate Director of Clinical Services
$90K - $97K *
Elevate clinical excellence by mentoring a dedicated team and driving operational success. Collaborate closely with leadership to ensure effective ABA service delivery and foster continuous developmen...
3 weeks ago
BCBA Associate Director of Clinical Services
$90K - $97K *
Lead clinical excellence and operational success by mentoring BCBAs, overseeing ABA programs, and ensuring high-quality service delivery, while fostering team growth and implementing strategies for co...
3 weeks ago
BCBA Associate Director of Clinical Services
$90K - $97K *
Join a team that's dedicated to developing clinical talent and driving operational excellence. Play a key role in leading ABA services, mentoring clinicians, and ensuring high-quality care and complia...
3 weeks ago
Senior Clinical Trial Operations Manager
$100K - $140K *
Engage in impactful clinical trial management, overseeing operations and mentoring teams to ensure quality and efficiency in project execution. Collaborate with leadership to drive improvements and ma...
Today
$100K - $120K *
Lead and shape the delivery of exceptional patient care by overseeing department operations, fostering team collaboration, and driving strategic initiatives in a dynamic hospital setting. Make a signi...
4 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.