Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

$80K - $95K *

Advance clinical operations by managing staff and programs, ensuring effective service delivery and compliance. Collaborate with leadership to enhance health initiatives and drive growth in clinical r...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$146K - $182K *

Partner with us to lead global regulatory submissions and document management. Drive operational excellence and compliance while collaborating with cross-functional teams to enhance processes and syst...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$146K - $182K *

Transform regulatory operations by leading global submissions and document management. Collaborate with cross-functional teams to ensure compliance and efficiency while driving continuous improvement...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$146K - $182K *

Advance your career by leading global regulatory submissions and document management. Drive compliance and efficiency while collaborating with cross-functional teams to enhance operational processes a...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K - $214K *

Join a team that's dedicated to leading and executing clinical trials. Leverage your expertise in clinical operations to manage projects from design to closeout, collaborating cross-functionally to en...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Contribute to operational excellence by overseeing revenue processes, enhancing patient satisfaction, and managing budgets. Lead initiatives to improve service quality and compliance while fostering a...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$98K - $101K *

Lead a team to develop and supervise consumer support services, ensuring high-quality care and compliance in an Intensive Rehabilitation Treatment Program focused on empowering individuals with mental...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Manage clinical trial operations, ensuring compliance and performance across protocols. Oversee submissions, budgets, and team coordination while collaborating with internal and external stakeholders...

Quebec, CARemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$112K - $225K *

Manage complex healthcare transformation projects, leading operational assessments and performance improvement initiatives. Collaborate with clinical and operational teams to deliver actionable recomm...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$112K - $225K *

Serve as a key resource in healthcare transformation, leading operational assessments and managing project teams to enhance clinical operations and performance across diverse healthcare settings...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$112K - $225K *

Transform healthcare delivery by leading clinical operations initiatives, managing complex projects, and driving performance improvements across diverse healthcare settings. Collaborate with stakehold...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$112K - $225K *

Transform healthcare operations by leading complex engagements, conducting assessments, and developing actionable strategies. Collaborate with multidisciplinary teams to enhance performance and drive...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$112K - $225K *

Drive healthcare transformation by leading clinical operations projects, managing multidisciplinary teams, and delivering actionable insights to enhance performance across diverse healthcare settings...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$147K *

Lead a dynamic team to optimize production operations, ensuring compliance and efficiency across campaigns. Collaborate with clients and partners to enhance quality and deliver results aligned with st...

1 week ago

  •   Less than 5 years exp.  •   Media

$92K - $125K *

Lead the design and scaling of clinical operations, ensuring high-quality mental health service delivery. Oversee compliance, performance metrics, and cross-functional collaboration to enhance operati...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Take ownership of operational leadership for a multidisciplinary care campus, ensuring safety, efficiency, and growth. Collaborate with diverse teams to implement strategic initiatives and enhance ser...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Engage in operational integration for newly acquired clinics, ensuring seamless transitions across clinical workflows, staffing, and facilities. Collaborate with cross-functional teams to optimize pro...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Champion integrated care by leading a team to enhance quality and access to healthcare for underserved communities. Drive innovation, manage staff, and ensure compliance while fostering a collaborativ...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$67K - $101K *

Lead the charge in overseeing patient care operations, ensuring compliance with regulations, enhancing agency profitability, and motivating staff to deliver high-quality home health services while coo...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Drive clinical operations effectiveness through leadership and teamwork, enhancing patient care. Supervise nursing staff while overseeing recruitment, training, and strategic initiatives across multip...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Lead the charge in enhancing patient care by overseeing Social Services operations, ensuring compliance, and fostering collaboration among multidisciplinary teams to deliver exceptional behavioral hea...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Elevate clinical operations by leading daily workflows, managing teams, and spearheading impactful projects. Drive improvement and efficiency in healthcare delivery while fostering collaboration acros...

New York, NYRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$219K - $235K *

Champion strategic clinical program leadership, ensuring high-quality execution and collaboration across teams to advance R&D initiatives and lifecycle management in a flexible hybrid work environment...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive excellence in clinical operations as a leader in an ambulatory surgery center, ensuring high-quality patient care, regulatory compliance, and operational efficiency while fostering a culture of...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a dynamic team to optimize clinical operations, ensuring compliance and performance excellence. Lead and develop Clinical Research Associates while managing resources and enhancing training initi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.