Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Associate Director, Clinical Scientist
$150K - $195K *
Champion the future of clinical science by leading trial design, data analysis, and cross-functional collaboration to ensure compliance with GCP and drive innovative solutions in rare disease research...
1 week ago
Associate Clinical Director Ambulatory
$110K - $130K *
Transform clinical operations by leading a dedicated team to enhance patient care, ensure compliance, and drive quality improvement initiatives across multiple practice sites, fostering a culture of e...
3 days ago
Director, Perioperative Services
$135K - $195K *
Elevate patient care by leading Perioperative Services with strategic oversight, enhancing operational efficiency, and fostering collaboration among clinical teams to ensure optimal service delivery a...
6 days ago
District Director of Clinical Services
$90K - $110K *
Lead the charge in strategic clinical oversight for skilled nursing operations, ensuring regulatory compliance and quality care delivery while training and supporting teams across multiple communities...
3 weeks ago
District Director of Clinical Services
$90K - $110K *
Partner with us to provide strategic clinical oversight in skilled nursing operations, ensuring regulatory compliance and quality care delivery while supporting management teams and optimizing resourc...
3 weeks ago
District Director of Clinical Services
$90K - $110K *
Lead the charge in providing clinical oversight within skilled nursing operations, ensuring quality care and compliance while supporting staff training and development. Collaborate closely with interd...
3 weeks ago
District Director of Clinical Services
$90K - $110K *
Transform healthcare operations by leading clinical oversight and ensuring regulatory compliance within skilled nursing communities. Optimize resources to enhance staff development and quality care de...
3 weeks ago
Associate Director / Director, Customer Program Management, Life Sciences
$148K - $224K *
Help us unlock the potential of therapeutic programs by leading project management across multidisciplinary teams, ensuring timely delivery, resource allocation, and clear communication with internal...
Reposted 6 days ago
Administrative Director - Ambulatory Surgery Center
$128K - $160K *
Join us in leading a dynamic team to enhance patient care and operational excellence in a multispecialty ASC environment. Drive quality improvement, ensure compliance, and foster a culture of safety a...
1 week ago
Executive Director of Clinical Services
$100K - $120K *
Champion exceptional patient outcomes by leading a dedicated clinical team. Oversee operational practices, implement value-based care, and ensure efficiency within the care group to enhance patient ex...
Today
Executive Director of Clinical Services
$100K - $120K *
Champion operational excellence by leading interdisciplinary teams to enhance patient outcomes and implement value-based care practices, ensuring alignment with organizational goals and fostering a co...
Today
$160K - $240K *
Lead and enhance program management capabilities, driving strategic initiatives and cross-functional collaboration to ensure successful project execution and alignment with company goals...
1 week ago
Director/Sr. Director of Special Projects, Clinical Strategy and Value Based Care
$129K - $205K *
Shape the future of clinical strategy and value-based care by leading cross-functional initiatives, collaborating with senior leaders, and driving impactful change in healthcare delivery and outcomes...
Reposted 6 days ago
Director/Sr. Director of Special Projects, Clinical Strategy and Value Based Care
$129K - $205K *
Join a team that's shaping the future of clinical care by leading strategic initiatives, enhancing healthcare delivery, and collaborating with senior leaders to drive impactful change in a dynamic env...
Reposted 1 week ago
$95K - $130K *
Lead the charge in clinical trial monitoring, ensuring compliance and quality through oversight, guidance, and collaboration with cross-functional teams to enhance site performance and study execution...
1 week ago
$115K - $135K *
Shape the future of clinical trials by leading site monitoring efforts, ensuring compliance, and fostering collaboration across teams. Drive quality and efficiency in trial execution while mentoring j...
2 weeks ago
$100K - $130K *
Elevate clinical trial success by overseeing site monitoring, ensuring compliance, and providing leadership. Collaborate with cross-functional teams to address site issues, enhance recruitment, and ma...
2 weeks ago
$100K - $130K *
Accelerate clinical trial success by leading site monitoring efforts, ensuring compliance, and providing expert guidance to the CRA team. Collaborate cross-functionally to resolve issues and enhance s...
2 weeks ago
$110K - $130K *
Lead clinical trial monitoring efforts, ensuring compliance and quality. Collaborate with cross-functional teams to address site issues, manage budgets, and provide oversight. Drive successful study e...
2 weeks ago
$250K - $300K *
Transform your career with a leadership role in physiatric care, blending remote oversight and on-site support. Guide clinical standards, enhance rehabilitation outcomes, and collaborate with multidis...
1 week ago
Executive Director, Clinical Supply Management
$280K - $300K *
Optimize clinical supply strategies and operations for transformative therapies. Lead a dynamic team, manage global partnerships, and ensure timely delivery of investigational products across multiple...
2 weeks ago
Executive Director, Clinical Supply Management
$280K - $300K *
Transform clinical supply management by leading strategy and execution for biologics programs. Drive team growth, ensure timely product delivery, and collaborate cross-functionally to meet ambitious c...
2 weeks ago
Executive Director, Clinical Supply Management
$280K - $300K *
Drive clinical supply strategy and execution for transformative therapies, leading a global team to ensure timely delivery of investigational products across multi-country studies, while collaborating...
2 weeks ago
Executive Director, Clinical Supply Management
$280K - $300K *
Join a dynamic team to lead clinical supply strategy and execution for transformative therapies. Shape and scale the Clinical Supply Management function, ensuring timely delivery of investigational pr...
2 weeks ago
Executive Director, Clinical Supply Management
$280K - $300K *
Shape the future of clinical supply management by leading strategy and execution for transformative therapies. Collaborate cross-functionally to ensure timely delivery of investigational products, whi...
2 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.