Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$150K - $195K *

Champion the future of clinical science by leading trial design, data analysis, and cross-functional collaboration to ensure compliance with GCP and drive innovative solutions in rare disease research...

San Diego, CARemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform clinical operations by leading a dedicated team to enhance patient care, ensure compliance, and drive quality improvement initiatives across multiple practice sites, fostering a culture of e...

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$135K - $195K *

Elevate patient care by leading Perioperative Services with strategic oversight, enhancing operational efficiency, and fostering collaboration among clinical teams to ensure optimal service delivery a...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Lead the charge in strategic clinical oversight for skilled nursing operations, ensuring regulatory compliance and quality care delivery while training and supporting teams across multiple communities...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Partner with us to provide strategic clinical oversight in skilled nursing operations, ensuring regulatory compliance and quality care delivery while supporting management teams and optimizing resourc...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Lead the charge in providing clinical oversight within skilled nursing operations, ensuring quality care and compliance while supporting staff training and development. Collaborate closely with interd...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Transform healthcare operations by leading clinical oversight and ensuring regulatory compliance within skilled nursing communities. Optimize resources to enhance staff development and quality care de...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$148K - $224K *

Help us unlock the potential of therapeutic programs by leading project management across multidisciplinary teams, ensuring timely delivery, resource allocation, and clear communication with internal...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$128K - $160K *

Join us in leading a dynamic team to enhance patient care and operational excellence in a multispecialty ASC environment. Drive quality improvement, ensure compliance, and foster a culture of safety a...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Champion exceptional patient outcomes by leading a dedicated clinical team. Oversee operational practices, implement value-based care, and ensure efficiency within the care group to enhance patient ex...

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Champion operational excellence by leading interdisciplinary teams to enhance patient outcomes and implement value-based care practices, ensuring alignment with organizational goals and fostering a co...

Today

  •   Less than 5 years exp.  •   Healthcare

$160K - $240K *

Lead and enhance program management capabilities, driving strategic initiatives and cross-functional collaboration to ensure successful project execution and alignment with company goals...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$129K - $205K *

Shape the future of clinical strategy and value-based care by leading cross-functional initiatives, collaborating with senior leaders, and driving impactful change in healthcare delivery and outcomes...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$129K - $205K *

Join a team that's shaping the future of clinical care by leading strategic initiatives, enhancing healthcare delivery, and collaborating with senior leaders to drive impactful change in a dynamic env...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $130K *

Lead the charge in clinical trial monitoring, ensuring compliance and quality through oversight, guidance, and collaboration with cross-functional teams to enhance site performance and study execution...

Boston, MARemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $135K *

Shape the future of clinical trials by leading site monitoring efforts, ensuring compliance, and fostering collaboration across teams. Drive quality and efficiency in trial execution while mentoring j...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Elevate clinical trial success by overseeing site monitoring, ensuring compliance, and providing leadership. Collaborate with cross-functional teams to address site issues, enhance recruitment, and ma...

Boston, MARemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Accelerate clinical trial success by leading site monitoring efforts, ensuring compliance, and providing expert guidance to the CRA team. Collaborate cross-functionally to resolve issues and enhance s...

Boston, MARemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead clinical trial monitoring efforts, ensuring compliance and quality. Collaborate with cross-functional teams to address site issues, manage budgets, and provide oversight. Drive successful study e...

Boston, MARemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$250K - $300K *

Transform your career with a leadership role in physiatric care, blending remote oversight and on-site support. Guide clinical standards, enhance rehabilitation outcomes, and collaborate with multidis...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$280K - $300K *

Optimize clinical supply strategies and operations for transformative therapies. Lead a dynamic team, manage global partnerships, and ensure timely delivery of investigational products across multiple...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$280K - $300K *

Transform clinical supply management by leading strategy and execution for biologics programs. Drive team growth, ensure timely product delivery, and collaborate cross-functionally to meet ambitious c...

Vancouver, BCIn-Person

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$280K - $300K *

Drive clinical supply strategy and execution for transformative therapies, leading a global team to ensure timely delivery of investigational products across multi-country studies, while collaborating...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$280K - $300K *

Join a dynamic team to lead clinical supply strategy and execution for transformative therapies. Shape and scale the Clinical Supply Management function, ensuring timely delivery of investigational pr...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$280K - $300K *

Shape the future of clinical supply management by leading strategy and execution for transformative therapies. Collaborate cross-functionally to ensure timely delivery of investigational products, whi...

Boston, MARemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.