Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$315K - $350K *

Tackle global mission delivery by leading operations across 260 locations. Empower a diverse team of 450+ while managing a $75M budget. Drive continuous improvement and innovation to enhance program i...

5 days ago

  •   11 - 15 years exp.  •   Staffing

$315K - $350K *

Unlock potential by leading global operations for a mission-driven nonprofit. Oversee 450+ staff and a $75M budget, driving continuous improvement and strategic initiatives across 260 locations to enh...

5 days ago

  •   11 - 15 years exp.  •   Staffing

$315K - $350K *

Partner with us to lead global operations for a mission-driven nonprofit, overseeing 450+ staff and a $75M budget. Drive innovation and continuous improvement across 260 locations, ensuring impactful...

5 days ago

  •   11 - 15 years exp.  •   Staffing

$210K - $250K *

Lead initiatives to enhance clinical outcomes and operational efficiency, acting as a physician advisor and liaison to optimize resource utilization and support medical staff in a dynamic healthcare e...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Champion clinical excellence by enhancing patient care and operational efficiency. Collaborate with medical staff to implement evidence-based practices, oversee performance improvement initiatives, an...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Take ownership of operational oversight for surgical services across multiple practices, ensuring compliance, quality improvement, and engagement while managing a diverse team for optimal performance...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Shape the future of our organization by ensuring seamless communication and decision-making across teams. As a strategic partner, drive high-priority projects and enhance operational effectiveness to...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$207K - $392K *

Advance your career by managing operations and driving growth, ensuring client satisfaction while developing key relationships with providers and stakeholders in a dynamic and supportive environment...

Illinois, USRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$446K - $500K+*

Lead the charge in advancing nursing excellence and quality patient care across a multi-campus health system. Collaborate with executives to implement strategic initiatives that enhance operational ef...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $220K *

Drive enterprise innovation and technology strategy to enhance federal market growth. Lead emerging tech investments, oversee R&D, and develop solutions that strengthen competitive positioning and del...

2 days ago

  •   11 - 15 years exp.  •   Staffing

$250K - $300K *

Champion the future of patient-centered care by leading clinical operations, enhancing population health, and fostering collaboration among healthcare teams to ensure high-quality, accessible services...

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Shape the future of senior healthcare by overseeing clinical operations, ensuring high-quality care delivery, managing staff, and implementing strategic initiatives across various settings with a focu...

Today

  •   Less than 5 years exp.  •   Healthcare

$233K - $267K *

Drive strategic initiatives as a senior leader in Clinical Practice Liaison, shaping team vision and performance. Collaborate with cross-functional teams to enhance medical strategy and ensure complia...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead a dynamic clinical operations team to enhance patient care delivery, ensuring compliance and operational excellence while fostering staff development and interdisciplinary collaboration for optim...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Lead impactful nursing programs to enhance patient care quality and efficiency. Collaborate with multidisciplinary teams to assess needs, implement educational initiatives, and drive clinical excellen...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Drive growth and innovation in clinical development, leading cross-functional teams to enhance therapeutic portfolios, particularly in cell and gene therapy, while ensuring medical oversight and strat...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Drive the growth of a therapeutic portfolio by leveraging medical expertise and overseeing clinical trials. Collaborate across teams to shape strategies in cell and gene therapy, ensuring innovative...

Covington, KYRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $156K *

Join a dynamic team as you oversee complex software deployments, ensuring governance and stakeholder engagement across multiple sites. Drive successful outcomes for strategic customers while managing...

Tucson, AZRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $156K *

Join us to oversee complex, multi-site software deployments, ensuring successful outcomes through governance and stakeholder management. Collaborate with teams and executives to drive programme succes...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$215K - $408K *

Join a team that's dedicated to enhancing medical management and quality improvement. Collaborate with clinical teams to optimize patient care, support performance initiatives, and drive effective uti...

Georgia, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$215K - $408K *

Lead the charge in enhancing medical management and quality improvement. Drive utilization review, collaborate with providers, and implement performance initiatives to optimize care quality and cost-e...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$276K - $500K+*

Lead the charge in clinical excellence by overseeing programs, enhancing patient care, and guiding a dedicated team. Collaborate with staff to innovate and evaluate services that meet the needs of div...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$276K - $500K+*

Lead the charge in shaping clinical excellence and oversight at a dynamic healthcare organization. Collaborate with diverse teams to enhance patient care, drive program innovation, and ensure complian...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$260K - $390K *

Lead the charge in shaping clinical excellence by overseeing programs, enhancing patient care, and guiding a dedicated team of medical professionals to innovate and improve health outcomes for diverse...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$260K - $390K *

Champion the clinical vision and oversight of diverse programs, ensuring quality care and productivity. Collaborate with staff and volunteers to innovate and evaluate initiatives that enhance patient...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.