Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$250K - $300K *

Lead the charge in designing and implementing a scalable home-based care model, ensuring high-quality, patient-centered care through interdisciplinary collaboration and continuous improvement across d...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$292K - $438K *

Empower healthcare excellence by leading clinical programs and teams. Utilize your extensive experience to enhance quality, compliance, and strategic initiatives in a dynamic environment focused on pa...

Eden Prairie, MNRemote

2 days ago

  •   11 - 15 years exp.  •   Healthcare

$210K - $260K *

Join a fast-paced team of medical professionals to evaluate and enhance service appropriateness through evidence-based guidelines, impacting quality patient outcomes across multiple specialties while...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$225K - $275K *

Elevate healthcare standards by guiding medical policy and coding within a collaborative team. Leverage your expertise to enhance client relationships, improve payment accuracy, and drive strategic in...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Join a team that's shaping clinical sales strategies and enhancing client relationships. Lead initiatives that drive market growth and improve patient satisfaction while collaborating across disciplin...

Harrisburg, PARemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$227K - $341K *

Lead the strategic development and continuous improvement of clinical programs, focusing on optimizing patient care across the continuum. Oversee a multidisciplinary team to enhance outcomes, reduce h...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$354K - $416K *

Elevate your career as a Medical Director, overseeing utilization management with a focus on clinical excellence and compliance. Collaborate with multidisciplinary teams to ensure high standards of ca...

West Virginia, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$200K - $250K *

Transform provider engagement by leading peer-to-peer conversations and ensuring clinical governance. Leverage your medical expertise to enhance patient safety and optimize drug strategies while repre...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by leading clinical reimbursement strategies across skilled nursing facilities, ensuring compliance and optimal performance through collaboration with multidisciplinary teams to enhan...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $140K *

Lead the charge in managing strategic clinical programs and customer relationships. Drive adoption, optimize workflows, and ensure account growth while delivering measurable value and fostering collab...

Boston, MARemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$207K - $392K *

Advance your career by managing operations and driving growth, ensuring client satisfaction while developing key relationships with providers and stakeholders in a dynamic and supportive environment...

Illinois, USRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Drive the growth of a therapeutic portfolio by leveraging medical expertise and overseeing clinical trials. Collaborate across teams to shape strategies in cell and gene therapy, ensuring innovative...

Covington, KYRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $156K *

Join a dynamic team as you oversee complex software deployments, ensuring governance and stakeholder engagement across multiple sites. Drive successful outcomes for strategic customers while managing...

Tucson, AZRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$215K - $408K *

Join a team that's dedicated to enhancing medical management and quality improvement. Collaborate with clinical teams to optimize patient care, support performance initiatives, and drive effective uti...

Georgia, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$215K - $408K *

Lead the charge in enhancing medical management and quality improvement. Drive utilization review, collaborate with providers, and implement performance initiatives to optimize care quality and cost-e...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$222K - $267K *

Transform healthcare through effective utilization management and collaborative leadership. Play a key role in developing policies ensuring high-quality patient care and cost containment within a dyna...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$210K - $250K *

Innovate in AI-native primary care by leading a dynamic medical group. Manage physicians, enhance care delivery, and shape clinical programs while maintaining direct patient care involvement. Drive ex...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in building and scaling clinical quality programs and population health strategies. Drive measurable improvements in quality outcomes and operational performance while fostering high-p...

Nashville, TNRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Join a dynamic team to lead and scale clinical operations, overseeing performance and process optimization. Build accountable teams, manage metrics, and partner with stakeholders to enhance operationa...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$107K - $199K *

Join a team that's driving strategic initiatives and operational excellence. This role collaborates with senior leadership to enhance growth plans, manage impactful projects, and ensure alignment acro...

Oregon, USRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $195K *

Innovate member experience strategies by translating enterprise goals into actionable plans. Drive performance improvements in CAHPS and HOS programs through provider engagement and data analysis, ens...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Join a dynamic team to optimize clinical operations, ensuring compliance and performance excellence. Lead and develop Clinical Research Associates while managing resources and enhancing training initi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $137K *

Empower healthcare organizations by translating complex data into actionable strategies. Collaborate with clinical teams to enhance performance metrics and optimize workflows, ensuring improved patien...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Drive enterprise-wide physician leadership and clinical oversight for government healthcare programs. Ensure high-quality, compliant healthcare services across federal detention facilities with a focu...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Staffing

$180K - $220K *

Take ownership of clinical integrity and quality oversight in population health management. Drive evidence-based standards and ensure compliance with accreditation requirements while collaborating wit...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.