Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$180K - $220K *

Advance clinical excellence by providing leadership and oversight in skilled nursing and long-term care facilities, ensuring high-quality, patient-centered care through collaboration with interdiscipl...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Elevate patient care by overseeing clinical operations, ensuring compliance with healthcare standards, and fostering a safe environment for staff and patients. Lead training initiatives and maintain h...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Lead clinical operations by ensuring compliance with healthcare standards, supervising patient care activities, and fostering a culture of quality and safety. Drive effective policies and training to...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Champion nursing excellence by leading ED operations, enhancing patient care, and fostering staff development. Drive quality outcomes and operational performance while ensuring compliance and high sat...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Take ownership of developing and leading training programs for Epic applications, ensuring effective end-user training and support. Collaborate with teams to create quality content and maintain traini...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Transform healthcare by leveraging your clinical expertise to enhance documentation quality, optimize reimbursement, and improve patient outcomes. Collaborate with diverse teams to drive compliance an...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Contribute to the successful adoption of Oracle Health systems by leading training, onboarding, and workflow optimization initiatives. Collaborate with clinical teams to enhance EHR usage, ensuring sa...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Lead the charge in enhancing specialty and geriatric services by providing physician leadership, ensuring quality care, and fostering collaboration with healthcare partners to meet patient needs and p...

Edmonton, ABIn-Person

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Transform crisis care by leading psychiatric services at a cutting-edge facility, overseeing treatment, mentoring staff, and fostering patient engagement within a multidisciplinary team dedicated to i...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$112K - $193K *

Lead the charge in managing multiple health centers, driving strategic growth, patient satisfaction, and operational excellence while overseeing financial performance and team development in a dynamic...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Lead global clinical operations to ensure timely delivery of complex clinical studies, fostering collaboration, and driving patient engagement while managing budgets and compliance effectively...

4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead clinical operations by providing direct patient care and mentoring staff. Collaborate with interdisciplinary teams to enhance patient outcomes and promote evidence-based practices in a dynamic he...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $200K *

Lead the charge in revolutionizing pharmacy operations, delivering strategic oversight, and ensuring regulatory compliance across multiple healthcare facilities, enhancing clinical quality and financi...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$155K - $259K *

Elevate your career by leading integrated optimization programs that enhance clinical, operational, and financial performance for healthcare clients. Drive measurable outcomes while managing diverse m...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$150K - $180K *

Join a team that's dedicated to shaping patient care by developing and overseeing nursing policies, ensuring compliance, and fostering collaborative leadership to enhance healthcare delivery and outco...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Elevate healthcare education by leading the development of innovative allied health programs. Drive growth and improvement through strategic partnerships, curriculum design, and compliance, ensuring l...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$85K - $95K *

Transform the lives of adolescents and families as a Clinical Director, overseeing clinical programming, guiding multidisciplinary teams, and ensuring high-quality behavioral health services for posit...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $168K *

Elevate your career by leading clinical studies from planning to execution. Collaborate with cross-functional teams to ensure compliance, quality, and timely delivery of study objectives while managin...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $145K *

Transform patient care services by leading a dedicated nursing team, ensuring quality delivery and operational efficiency while fostering interdepartmental collaboration and staff development...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $150K *

Lead the charge in operational excellence and strategic growth within a mission-driven organization. Drive quality care across multiple facilities while fostering collaboration, accountability, and co...

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Champion effective technology solutions by leading healthcare IT project implementations. Collaborate with cross-functional stakeholders to navigate risks and maintain project alignment, ensuring time...

New Jersey, USRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$136K - $218K *

Oversee daily clinical operations to enhance patient care delivery, ensure regulatory compliance, and develop staff. Foster interdisciplinary collaboration while achieving service excellence and strat...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$136K - $218K *

Lead the charge in clinical nursing practice by managing operations, resources, and personnel to ensure exceptional patient care, compliance, and service excellence in a collaborative, interdisciplina...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Champion clinical education excellence by leading partnerships and ensuring alignment with accreditation standards, enhancing student learning outcomes across nursing programs through strategic oversi...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Lead the charge in enhancing clinical education by overseeing partnerships, ensuring compliance with accreditation standards, and fostering faculty development to elevate student learning outcomes acr...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.