Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.

California industries and career opportunities

California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.

Find jobs throughout the state

Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.

Search with Ladders

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$80K - $95K *

Transform customer relationships by driving strategic account growth, enhancing engagement, and achieving sales targets. Collaborate with cross-functional teams to meet client needs and deliver except...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$124K - $186K *

Champion operational excellence by ensuring accurate documentation and inventory for deployed assets. Collaborate with cross-functional teams to resolve issues, maintain records, and enhance fleet rea...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$80K - $95K *

Drive growth by managing strategic accounts, enhancing relationships, and achieving sales targets. Collaborate with teams to meet customer needs and develop tailored solutions while ensuring high sati...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$125K - $150K *

Join a dynamic team to design and develop mission-critical flight software for spacecraft. Contribute to all phases of the software lifecycle, ensuring successful satellite operations through innovati...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$135K - $165K *

Join us to design and develop backend systems for AI-driven industrial robotics, enhancing automation solutions. Collaborate with cross-functional teams to build robust infrastructure and data pipelin...

Today

  •   Less than 5 years exp.  •   Information Technology

$105K - $120K *

Drive impactful research initiatives by leading complex projects, mentoring teams, and securing new business opportunities. Collaborate with diverse stakeholders to deliver high-quality evaluations an...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Drive compliance and sustainability by advising clients on environmental regulations, managing projects, and developing practical solutions. Collaborate with teams to ensure adherence to air, stormwat...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Technical Services

$95K - $115K *

Join us to lead educational excellence as a principal, overseeing daily operations, staff development, and student engagement while fostering a positive learning environment and managing budgets effec...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Empower legal firms by leading the development of innovative IT solutions, driving market strategies, and enhancing service offerings. Collaborate with cross-functional teams to establish credibility...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$340K - $400K *

Take ownership of building a comprehensive kidney and liver transplant program, fostering collaboration across multidisciplinary teams to ensure exceptional clinical outcomes and patient-centered care...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$85K - $90K *

Manage board relations and special projects, ensuring effective communication and support for the Executive Director. Collaborate across teams to execute organizational priorities and enhance governan...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$130K - $155K *

Shape innovative Salesforce solutions by leading design and delivery across multiple clouds. Engage with clients to gather requirements, document solutions, and guide implementation teams in a fully r...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$68K - $114K *

Join a team that's dedicated to ensuring compliance through EMC and EMI testing. Collaborate on new designs and sustain projects while developing test procedures and documentation to meet regulatory s...

Today

  •   Less than 5 years exp.  •   Consumer Technology

$135K - $160K *

Unlock your potential as a Solution Architect, leading CRM design and integration for pharma and biotech. Drive innovation with Veeva CRM and Salesforce, ensuring seamless operations and client engage...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $125K *

Join a dynamic surgical team as you provide essential support during complex procedures. Prepare instruments, assist surgeons, and ensure patient safety while maintaining aseptic techniques in a fast...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$216K - $243K *

Pioneer advancements in vaccine research and development, driving global immunization efforts. Collaborate across teams to ensure compliance and effective delivery of safe vaccines, enhancing public h...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $93K *

Grow your career with a dynamic Finance team as a Staff Accountant, supporting financial operations for R&D programs and USG contracts. Collaborate across departments to ensure accurate financial reco...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a team that's dedicated to overseeing construction analysis and damage verification for disaster-affected properties. Lead and mentor a skilled workforce while ensuring compliance with policies a...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Join a team that's shaping the future of information technology by leading hardware strategy and integration for critical systems. Drive innovation and ensure operational excellence throughout the lif...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$70K - $110K *

Lead the charge in maximizing revenue through strategic sales initiatives and exceptional customer service in the trench safety equipment rental sector, while developing strong relationships with cont...

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Lead the execution of clinical trials by monitoring site activities, ensuring compliance with regulations, and collaborating with teams to achieve study objectives. Play a key role in training site st...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate your career by leading Infor M3 ERP implementations. Drive project success through strategic planning, client management, and cross-functional collaboration while ensuring timely delivery and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$177K - $353K *

Unlock potential by taking ownership of your sales region, driving growth through proven closing techniques and warm leads. Enjoy independence, uncapped commission, and a supportive environment that v...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $85K *

Join a team that's dedicated to developing future leaders in health services. This program offers licensed nurses comprehensive training and mentorship to transition into Health Services Director role...

Today

  •   Less than 5 years exp.  •   Healthcare

$174K - $204K *

Transform global scientific publication activities by leading strategy, overseeing processes, and ensuring compliance while driving innovation through data and vendor management for impactful scientif...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.

  • Where in California can I search for jobs?question toggle

    You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.

  • Can I find remote or hybrid California jobs?question toggle

    Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.

  • How can I improve my California job search?question toggle

    Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.