Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.

California industries and career opportunities

California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.

Find jobs throughout the state

Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.

Search with Ladders

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.

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1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$170K - $200K *

Lead the charge in defining and implementing procurement strategies for our innovative space startup, driving competitive advantages in the electrical supply chain while coaching a high-performance te...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$88K *

Manage financial analysis and compliance for grants, ensuring accuracy and adherence to regulations. Collaborate with teams to prepare reports, budgets, and audits while enhancing processes for effici...

2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$165K - $185K *

Manage and oversee the operational execution of clinical studies, ensuring compliance with protocols and regulations while coordinating with vendors and teams to drive successful trial outcomes...

San Diego, CARemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Deliver strategic legal counsel while managing commercial contracts and compliance. Collaborate with executive leadership and stakeholders, mitigate risks, and support corporate legal needs across var...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Staffing

$200K - $250K *

Engage as a strategic legal advisor providing counsel on commercial contracts, compliance, and corporate law. Oversee risk management while supporting corporate transactions, ensuring legal integrity...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Staffing

$203K - $319K *

Lead and optimize commercial operations to drive growth, enhance revenue strategies, and streamline processes. Collaborate with cross-functional teams to ensure effective execution of sales initiative...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$88K *

Lead the charge in financial analysis and grant management, ensuring compliance and accuracy in reporting. Collaborate with teams to enhance processes and support effective budget development for dive...

2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $160K *

Shape the future of healthcare by delivering advanced clinical training and optimizing ultrasound solutions. Collaborate with diverse teams to enhance educational content and drive project success whi...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$77K - $103K *

Champion the management of complex legislative and election processes, overseeing the City’s records program while supporting the City Clerk in fulfilling essential duties and ensuring compliance with...

2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$77K - $87K *

Manage payroll and benefits administration, ensuring accuracy and compliance in a dynamic setting. Provide exceptional support to employees while maintaining meticulous records and facilitating covera...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Transform clinical research operations by leading studies, managing sites, and ensuring compliance. Collaborate cross-functionally to drive successful execution of clinical programs while maintaining...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $103K *

Empower environmental compliance by overseeing monitoring systems, conducting audits, and managing vendor relationships. Collaborate with teams to ensure adherence to regulations while enhancing opera...

2 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$187K - $260K *

Lead the charge in shaping our marketing technology ecosystem, driving product strategy and team development while enhancing workflows and cross-channel capabilities for data-driven marketing success...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$74K - $100K *

Drive operational excellence by overseeing clinic management, staff supervision, and program development. Collaborate with leadership to enhance healthcare services, ensuring quality outcomes and pati...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$74K - $100K *

Drive operational excellence as a Clinic Supervisor, overseeing staff and enhancing healthcare services. Collaborate with leadership to ensure quality care, efficient operations, and optimal patient s...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$207K - $276K *

Lead the charge in defining cloud engineering strategy and architecture standards. Drive complex initiatives across teams, ensuring scalable, secure, and cost-effective cloud solutions while mentoring...

2 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$98K - $131K *

Join a team that's redefining corporate governance and SEC compliance. In this role, you'll manage board administration, support SEC filings, and integrate innovative legal technologies to enhance eff...

2 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$179K - $253K *

Transform data integrity and analytics for payments and trust systems, ensuring reliable metrics and quality insights. Lead technical initiatives, collaborate with cross-functional teams, and enhance...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Media

$179K - $253K *

Optimize data integrity and analytics for payments and trust systems. Lead technical initiatives, ensuring reliable metrics and models while collaborating with cross-functional teams to enhance decisi...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Media

$80K - $95K *

Empower scientific innovation by providing expert installation and maintenance of advanced analytical equipment. Build strong customer relationships while resolving complex issues and ensuring optimal...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join a dynamic team to tackle complex healthcare challenges by developing full-stack solutions. Collaborate with cross-functional teams to define problems, implement features, and integrate AI, ensuri...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$158K - $185K *

Join our team to manage global data generation for innovative cancer therapies. Oversee operational aspects of clinical studies, collaborate with cross-functional teams, and ensure timely project exec...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$92K - $115K *

Champion digital marketing initiatives to enhance brand presence, drive engagement, and optimize member experiences across all channels. Collaborate with teams to develop strategies, manage campaigns...

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$136K - $184K *

Join a team that's redefining network infrastructure by designing and operating scalable solutions across diverse environments, ensuring reliability and efficiency while enabling rapid engineering adv...

2 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$115K - $135K *

Drive innovative electrical design for data center projects, leading multidisciplinary teams to ensure project success. Manage schedules, budgets, and deliverables while mentoring junior engineers and...

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.

  • Where in California can I search for jobs?question toggle

    You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.

  • Can I find remote or hybrid California jobs?question toggle

    Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.

  • How can I improve my California job search?question toggle

    Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.