Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$110K - $130K *
Accelerate progress at the forefront of rubber and tire technology innovations. Leverage your expertise to drive product development, influence strategy, and lead research initiatives in a role that s...
4 weeks ago
$110K - $130K *
Join us to innovate in microwave engineering, collaborating on advanced HPM devices and systems. Leverage your expertise in simulation and design while contributing to vital defense projects in a dyna...
2 weeks ago
$80K - $95K *
Lead the charge in advancing in vitro and in vivo release testing through method development and compliance with FDA regulations. Engage with cross-functional teams to ensure timely project delivery a...
3 weeks ago
$212K - $393K *
Elevate your impact by defining the technical vision for AI-driven search and knowledge systems. Lead the development of innovative capabilities while collaborating with cross-functional teams to deli...
2 weeks ago
$111K - $160K *
Lead the charge in advancing solid-state battery technologies by developing innovative polymer materials, designing complex experiments, and analyzing data to drive key product enhancements and strate...
2 weeks ago
(Senior / Principal) Scientist, Therapeutic Discovery
$150K - $180K *
Join a team that's shaping the future of health by leading innovative therapeutic programs from concept to validation, ensuring scientific rigor and strategic execution while driving meaningful advanc...
2 days ago
Managing Scientist (Regulatory)
$127K - $156K *
Unlock potential by leading regulatory compliance projects, enhancing client relationships, and mentoring junior staff. Collaborate with experts to deliver innovative solutions across diverse industri...
1 week ago
Principal Regulatory Scientist
$120K - $145K *
Shape the future of regulatory science by leading projects, nurturing client relationships, and driving business growth in environmental compliance. Utilize your expertise in chemical regulation to de...
4 weeks ago
$120K - $145K *
Unlock potential by leading innovative research in particle technology and separation materials. Drive scientific advancements and mentor teams while shaping the future of chromatography for diverse a...
2 days ago
$115K - $145K *
Innovate purification solutions for biopharmaceuticals through advanced chromatography. Lead high-throughput experimentation and cross-functional collaboration to enhance bioprocessing performance and...
Reposted 2 weeks ago
$110K - $130K *
Join our team to drive hands-on research in synthetic phage engineering, focusing on molecular biology workflows, experimental design, and data analysis to advance innovative solutions in a collaborat...
1 week ago
$105K - $130K *
Lead the charge in innovative product development, driving projects from insights to launch while collaborating with cross-functional teams to deliver impactful solutions that meet consumer and market...
1 week ago
Research and Technology Innovation Scientist
$80K - $95K *
Contribute to innovative research and product development with cross-functional teams. Support project management and market analysis, ensuring timely execution and alignment across R&D, legal, clinic...
Yesterday
Senior Scientist - Applications R&D
$95K - $115K *
Engage as a technical expert in bioprocessing, driving innovative solutions and collaboration across R&D, marketing, and commercial teams to enhance customer adoption of advanced ion exchange and sepa...
2 days ago
Senior Scientist - Applications R&D
$95K - $115K *
Unlock innovative solutions as a customer-facing expert in bioprocessing, leveraging your scientific knowledge to solve complex challenges and drive business growth across diverse applications in ion...
2 days ago
Lead Scientist, GenAI & Research Enablement
$125K - $165K *
Champion large-scale research through cloud and GenAI technologies. Lead initiatives, foster collaboration across diverse communities, and drive the adoption of advanced computational capabilities to...
2 weeks ago
Scientist/Sr. Scientist/Principal Scientist
$110K - $130K *
Innovate in process chemistry by leading research, optimizing routes, and supporting GMP manufacturing for small-molecule APIs. Drive technical strategies and mentor a team while collaborating with cr...
3 weeks ago
Principal Scientist, Biomarker Bioanalytical Sciences
$141K - $188K *
Unlock potential by leading biomarker and bioanalytical strategies to support clinical development. Collaborate with internal teams and CROs, ensuring scientifically rigorous approaches are aligned wi...
3 weeks ago
Principal Scientist, Biomarker Bioanalytical Sciences
$141K - $188K *
Empower clinical development through scientific leadership in biomarker and bioanalytical strategies, guiding assay design, CRO oversight, and regulatory submissions in a fast-paced environment...
3 weeks ago
$120K - $145K *
Join our innovative team as a Product Scientist, applying your expertise in computational and medicinal chemistry to optimize small molecules and drive partner programs forward, while shaping the futu...
1 month ago
$120K - $145K *
Lead scientific partnerships, optimizing small molecule therapies using your expertise in medicinal chemistry and computational methods. Collaborate across disciplines to develop innovative modeling s...
1 month ago
Senior Scientist - Product Development
$110K - $130K *
Optimize product innovation by leading cutting-edge development programs that enhance the Tyvek® portfolio, all while collaborating with cross-functional teams to deliver customer-driven solutions and...
2 days ago
Principal Research Scientist - Risk
$150K - $180K *
Champion innovative research initiatives in infrastructure risk modeling and resilience, leading a skilled team to enhance utilities' decision-making processes with advanced statistical and predictive...
1 week ago
Principal AI Scientist and Lead
$150K - $180K *
Lead the development of innovative AI solutions in preclinical research, managing complex predictive models and agentic systems. Collaborate with stakeholders to ensure secure deployment and complianc...
Reposted 3 days ago
Senior Scientist I Analytical Development
$112K - $135K *
Lead the charge in analytical development for small molecule CMC projects, enhancing quality control and regulatory compliance from preclinical through late-stage clinical phases, while collaborating...
Reposted 1 week ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.