Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Account Director Jobs in Missouri

Sort By: Relevance

$150K - $195K *

Contribute to the success of IVD and CDx programs by leading cross-functional teams through development, validation, and submission processes. Drive strategic execution and ensure alignment with regul...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K - $205K *

Transform the U.S. sales landscape by driving strategic account plans and fostering relationships in the kidney transplant sector, ensuring optimal product utilization and achieving revenue targets th...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Join us as a strategic advisor, providing legal counsel on commercial contracts, AI products, and technology licensing. Collaborate with cross-functional teams to drive proactive solutions and support...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$100K - $120K *

Join a dynamic team to build and execute innovative ABM programs that engage and grow strategic accounts. Collaborate with sales and marketing to create personalized experiences that drive pipeline an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$180K - $215K *

Elevate regional sales performance by leading a high-impact team, executing strategic launches, and fostering key customer relationships in a dynamic, fast-paced environment. Drive accountability and...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Empower customer success by managing strategic accounts, driving growth, and ensuring satisfaction. Build relationships, analyze data, and collaborate cross-functionally to exceed goals and mitigate r...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $230K *

Drive impactful oncology solutions by building relationships with key stakeholders. Collaborate with internal teams to enhance patient access and exceed performance goals while managing territory reso...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$210K - $258K *

Unlock your potential as a Senior Engagement Manager, leading complex consulting projects for pharmaceutical clients. Drive strategic medical initiatives, foster client relationships, and mentor teams...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Contribute to quality operations initiatives by reviewing study documents, supporting audits, and ensuring compliance with regulatory standards. Collaborate with cross-functional teams to enhance qual...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$71K - $100K *

Drive strategic initiatives by analyzing market trends and performance metrics. Collaborate with cross-functional teams to develop business cases and forecasts, ensuring data integrity and delivering...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$216K - $361K *

Drive customer retention and growth by managing strategic accounts, collaborating cross-functionally to enhance customer experiences, and achieving revenue targets through effective account planning a...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Shape high-impact growth in retail partnerships by overseeing field operations, driving application volume, and enhancing point-of-sale conversion rates. Collaborate with teams to optimize strategies...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$180K - $215K *

Unlock regional growth by leading a high-performing sales team, executing launch strategies, and fostering key customer relationships in a dynamic, fast-paced environment. Drive performance and ensure...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Drive portfolio value creation through strategy execution, leveraging your extensive experience in revenue growth and go-to-market capabilities to lead engagements and mentor GTM teams across technolo...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Transform your career by driving growth in commercial real estate financing. This role focuses on originating and structuring loans while building strong relationships with clients and industry profes...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Transform compensation and rewards at scale, ensuring fairness and clarity across global teams. Collaborate with leadership to design and implement effective pay structures, cycles, and equity guideli...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$120K - $180K *

Unlock potential by leading full-cycle sales in the corrections sector, driving innovative drone solutions. Collaborate with diverse teams to build trust and pipeline, while navigating complex agency...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$84K - $135K *

Grow your career by delivering tailored energy solutions to commercial clients. Utilize your sales expertise in the deregulated market while cultivating long-term partnerships and engaging with divers...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $120K *

Join a team that's transforming patient care access by owning the mid-market and enterprise pipeline, building partnerships, and navigating complex deals to drive impactful growth in a collaborative s...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$110K - $160K *

Drive your career with a strategic role in Product Operations, partnering with leaders to transform complex challenges into actionable insights, while enhancing cross-functional collaboration and leve...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$138K - $172K *

Empower revenue teams as a Senior Business Systems Analyst, driving efficiency through Salesforce architecture, process design, and actionable data across GTM, Marketing, Sales, and Customer Success o...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$200K - $270K *

Shape the future of immunotherapy by leading access strategies for a groundbreaking T-cell therapy. Collaborate with cross-functional teams to ensure timely payer engagement and coverage decisions, ma...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $250K *

Champion innovation by optimizing workflows and AI-driven operations to enhance efficiency across diverse business functions. Collaborate closely with teams to build scalable systems that drive real i...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $215K *

Collaborate with senior leaders to design and implement global HR strategies, driving organizational performance and employee engagement while leading a team of HR professionals in a dynamic environme...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Lead the charge in shaping pricing strategy for a key region, overseeing a talented team to drive profitable growth while navigating complex regulatory environments and leveraging data for strategic d...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.