Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Manager of Account Management, Large Group Segment - Cigna Global Health Benefits (GHB) - Remote
$110K - $130K *
Develop strategic leadership for a team managing complex client portfolios, driving retention, growth, and client experience objectives while fostering strong relationships with stakeholders and ensur...
1 week ago
Commercial Account Executive (Enterprise)
$110K - $130K *
Champion enterprise growth by driving strategic account expansion and retention. Collaborate with cross-functional teams to influence executive stakeholders and execute complex sales strategies, ensur...
Reposted 5 days ago
Supervisor, Media Strategy & Client Partnerships
$102K - $122K *
Champion client partnerships by driving strategic media campaigns and fostering relationships. Leverage your expertise in DTC paid media to enhance client success and team collaboration, ensuring impa...
Reposted today
$110K - $130K *
Join a dynamic team to lead tax engagements, consult on planning, and develop talent. Shape client success through strategic management and industry expertise while fostering a collaborative environme...
2 weeks ago
$110K - $130K *
Advance client success by leading tax engagements, mentoring teams, and driving strategic solutions. Leverage your expertise to enhance business processes and foster growth in a collaborative environm...
2 weeks ago
New Product Planning Associate Director - Biopharma
$162K - $203K *
Shape the future of biopharma by leading commercial strategies for CNS pipeline programs, integrating R&D insights, and guiding investment decisions to ensure clinical and market success across multip...
4 weeks ago
$126K - $150K *
Champion growth strategies for net-new business, driving critical sales across cyber threat intelligence. Influence Fortune 1000 leaders in high-stakes environments while navigating complex sales cycl...
Reposted 1 week ago
Sales Manager/Key Account Manager (East Coast)
$125K - $200K *
Lead the charge in driving sales growth across the East Coast by developing new accounts and implementing strategic sales initiatives. Collaborate with customers to deliver tailored solutions and achi...
3 weeks ago
Director, Medical Writing - Market Access Promotional Agency
$117K - $165K *
Lead the charge in developing strategic medical content while collaborating cross-functionally and ensuring high standards of accuracy and clarity, influencing multiple therapeutic projects for a dive...
Reposted today
$80K - $100K *
Champion client success by managing relationships with family law firms. Drive strategic conversations, align business goals, and leverage insights to enhance growth and performance across your portfo...
3 weeks ago
Senior Manager, Lifecycle Marketing
$181K - $245K *
Elevate your career by leading lifecycle marketing strategies that enhance customer engagement, retention, and monetization. Drive impactful programs while managing a high-performing team and collabor...
1 week ago
Senior Design Manager - Business Banking & Investments
$228K - $285K *
Transform the design landscape by leading a talented team to elevate visual and interaction quality in financial software. Drive innovation, simplify complex workflows, and inspire designers to delive...
6 days ago
$125K - $150K *
Shape the future of affordable housing by managing LIHTC transactions from underwriting to closing. Collaborate with developers and investors to ensure timely execution and sound investment recommenda...
2 days ago
Select Major Account Executive (CST)
$350K *
Unlock potential by driving revenue growth through strategic relationships with enterprise customers. Engage in complex sales cycles, championing customer success while thriving in a high-performance...
Reposted 2 days ago
Senior Director, Contact Center
$150K - $180K *
Lead the future of patient experience by driving strategic initiatives and operational excellence in a high-volume healthcare contact center. Collaborate with cross-functional teams to enhance service...
Reposted 6 days ago
Account Executive, Broker Channel (St. Louis)
$123K - $205K *
Unlock potential by driving strategic partnerships with insurance brokers, managing a dynamic sales pipeline, and achieving consistent quota attainment. Shape the future of the channel program while e...
3 weeks ago
Director of Business Development (DBD) Acute Care Hosp. (LTCH)
$100K - $120K *
Grow your career by leading a team of Clinical Liaisons, managing a territory, and driving admissions in a dynamic healthcare environment. Cultivate relationships and execute market strategies to enha...
2 weeks ago
Senior Financial Analyst (Product & Delivery)
$100K - $120K *
Drive financial excellence by integrating and analyzing revenue and expense forecasts, ensuring alignment across functions. Collaborate with FP&A teams to deliver actionable insights and support strat...
3 weeks ago
$125K - $150K *
Join a team that's redefining enterprise sales by engaging C-suite stakeholders in Tier 1 banks and credit unions. Drive complex sales cycles, build strategic relationships, and deliver tailored solut...
1 week ago
Enterprise Account Executive - Warehouse Robotics (North America)
$150K *
Champion new business across North America by selling autonomous mobile robots. Own the sales process, develop complex relationships, and structure high-value agreements, while driving innovative stra...
Reposted 2 days ago
$150K - $180K *
Elevate your career by leading client relationships and driving revenue growth for consumer product brands in the D2C ecommerce space. Utilize your expertise to coach teams, innovate strategies, and o...
Reposted 4 days ago
Director of Retirement Sales Activation
$130K - $140K *
Drive efficiency and scalability in onboarding processes, enhancing customer experience through innovative strategies and data-driven leadership. Lead a high-performing team to optimize resources and...
3 weeks ago
$200K *
Lead the charge in building and scaling AI Data Operations, transforming emerging opportunities into commercially viable solutions. Drive strategy, partnerships, and operational excellence to support...
4 weeks ago
Business Development Manager - EU
$109K - $186K *
Champion business growth across European defense markets by developing strategies, engaging stakeholders, and managing sales cycles. Build long-term relationships to position solutions as the preferre...
Reposted 1 week ago
$109K - $164K *
Drive advanced digital forensics and incident response initiatives while mentoring a skilled engineering team. Leverage deep technical knowledge to enhance operational capabilities and ensure exceptio...
Reposted 2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.