Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Strategic Account Manager (South Central)
$173K - $225K *
Drive strategic partnerships with healthcare organizations to enhance care for rare kidney diseases. Collaborate with cross-functional teams to align clinical and operational goals, ensuring impactful...
Yesterday
Senior Director of Strategic Planning and Analysis
$185K - $315K *
Join us to shape strategic financial planning and analysis, leveraging AI to enhance forecasting and decision-making. This high-impact role collaborates with executives, driving insights that align wi...
5 days ago
$180K - $220K *
Empower growth in Generative AI by building relationships, driving revenue, and collaborating cross-functionally to deliver innovative solutions while achieving client satisfaction and sales targets i...
Reposted 3 weeks ago
Account Executive - Southern California
$70K - $110K *
Accelerate account growth by driving new customer acquisition and managing key district partnerships in the K-12 education market, while delivering teletherapy solutions and ensuring exceptional custo...
Reposted today
$120K - $140K *
Join a dynamic team as you take ownership of the accounting function, managing spend, payables, and reconciliations. Drive process improvements and leverage AI to enhance workflows, ensuring accuracy...
5 days ago
Sr. Manager, Strategy Operations
$80K - $105K *
Empower your career by leading strategy operations, collaborating with cross-functional teams, and driving innovative solutions. This role offers the chance to enhance agency performance while mentori...
2 weeks ago
$110K - $130K *
Drive growth by managing strategic enterprise accounts, cultivating relationships, and delivering tailored solutions that align with client objectives while exceeding sales targets and enhancing custo...
2 weeks ago
Sr Director, Product Management
$160K - $200K *
Drive the evolution of dealer marketing solutions by leading product management efforts, overseeing current offerings, and defining a next-gen platform that enhances customer engagement and retention...
5 days ago
Associate Account Executive (St. Louis)
$75K - $95K *
Discover new business opportunities by leveraging relationships and executing consultative sales strategies. Collaborate with cross-functional teams to drive growth and enhance client engagement in a...
4 days ago
$138K - $214K *
Optimize project outcomes by leading preconstruction efforts for large-scale Data Center initiatives. Drive team performance, manage budgets, and ensure exceptional client relationships while overseei...
6 days ago
$138K - $214K *
Shape the future of data center projects by leading preconstruction efforts, ensuring optimal financial positioning, and fostering strong team collaboration to deliver exceptional results and client s...
6 days ago
$115K - $130K *
Lead the Archibus platform for a major Life Sciences client, driving enhancements and integrations while ensuring data integrity and user satisfaction. Collaborate with cross-functional teams to optim...
1 week ago
New Business Development Director - Healthcare Finance (Oracle / Workday ERP)
$136K - $237K *
Transform healthcare finance by leading ERP sales initiatives, driving new opportunities with Oracle and Workday. Leverage deep industry knowledge to enhance client relationships and deliver innovativ...
Today
Account Executive - Pacific Northwest
$100K - $120K *
Shape the future of traffic management by driving revenue through strategic partnerships with government agencies. Cultivate relationships, identify opportunities, and execute sales strategies to meet...
1 week ago
$150K - $180K *
Shape the future of billing operations by leading a team to enhance accuracy, timeliness, and efficiency. Drive process improvements, manage complex accounts, and collaborate across functions to resol...
1 week ago
$115K - $185K *
Lead the charge in optimizing hospital accounts receivable operations, driving cash acceleration, reducing denials, and enhancing revenue realization through strategic partnerships and data-driven dec...
5 days ago
Director of Sales, Pacific Northwest - Remote (PST)
$200K - $300K *
Accelerate sales growth in the Pacific Northwest by leading a dynamic team in Washington, Oregon, and Idaho. Drive accountability, enhance pipeline management, and foster a high-performance culture th...
Reposted 1 week ago
$120K - $145K *
Help us shape the future of our brand by leading creative initiatives across campaigns, digital channels, and events. Collaborate with marketing teams to ensure a consistent visual identity and impact...
3 weeks ago
$250K - $300K *
Join a dynamic team as you drive enterprise sales across mid-market to Fortune 500 accounts. Own the entire sales cycle, engage multi-stakeholder buying committees, and leverage AI tools to redefine b...
5 days ago
$180K - $190K *
Deliver innovative solutions by acquiring Fortune 500 clients, leading complex sales cycles, and building executive relationships. Drive value through AI insights and strategic partnerships, ensuring...
1 week ago
$160K - $185K *
Join a team that's redefining the SaaS landscape by driving strategic growth and closing high-value deals. Engage with senior leaders, develop a robust pipeline, and collaborate cross-functionally to...
Reposted 4 days ago
$165K *
Join us to lead a dynamic Sales Development team, driving pipeline growth through strategic outbound and inbound initiatives. Collaborate with cross-functional teams to enhance performance and leverag...
3 weeks ago
Senior Director, Identity and Access Management
$251K - $297K *
Lead the charge in defining and executing a modern identity strategy for a large enterprise, enhancing IAM maturity and user experience while managing diverse identity and security technologies across...
Yesterday
Senior Strategist, Paid Search (DTC)
$85K - $106K *
Empower clients by leading innovative paid search strategies across diverse categories. Collaborate with cross-functional teams to drive performance, optimize campaigns, and connect search tactics to...
1 week ago
Senior Director, Client Partner
$152K - $203K *
Elevate client partnerships by uncovering growth opportunities and building trusted executive relationships. Drive strategic conversations that connect client needs to innovative solutions, fostering...
Yesterday
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.