Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Account Director Jobs in Missouri

Sort By: Relevance

$90K - $110K *

Empower strategic growth by managing key accounts across diverse sectors. Drive revenue, enhance client relationships, and deliver integrated solutions while collaborating with global teams to ensure...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$180K - $220K *

Lead the charge in driving growth for our Guidewire InsuranceNow practice by developing strategic relationships, generating new business opportunities, and executing revenue strategies across the US i...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$80K - $95K *

Engage with mid-market clients to drive consultative sales, managing the full cycle from outreach to contract. Build trust with support leaders, demonstrating clear ROI and shaping the sales strategy...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $230K *

Unlock potential by driving new business in the Insurance sector with your sales expertise. Collaborate across teams to develop solutions that address client needs and position the firm as a leader, w...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Information Technology

$150K - $180K *

Unlock potential by driving digital transformation in Life Sciences. Engage with CxOs and R&D teams to deliver innovative SaaS solutions, navigate complex sales cycles, and build lasting partnerships...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the charge in managing and selling Table Games and ETGs to casino operators, enhancing customer satisfaction while maintaining strong relationships and achieving sales targets within your territo...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Consumer Technology

$110K - $170K *

Champion growth by managing strategic partnerships with enterprise service professionals. Leverage data-driven insights to drive retention and revenue, while building trusted relationships with execut...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$120K - $150K *

Shape the future of brand strategy by leading integrated initiatives, translating insights into actionable plans, and collaborating with cross-functional teams to deliver impactful solutions across as...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $100K *

Drive your career forward by managing key partnerships and delivering measurable results. This role blends strategic relationship management with consultative selling, ensuring partner success and gro...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $200K *

Shape the future of internal audit by leading compliance initiatives, managing SOX and MAR activities, and enhancing internal controls across the organization. Collaborate with teams to drive risk man...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$230K - $345K *

Lead the charge in shaping global Total Rewards strategies that attract, retain, and reward talent across diverse markets. Collaborate with senior leaders to build scalable, equitable programs while g...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$100K *

Drive growth and strengthen relationships in Broker-Dealer and RIA channels. Consult with financial professionals on investment solutions, deliver market insights, and support business development ini...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$300K - $350K *

Engage in a dynamic sales role, driving the full cycle from pipeline generation to closing six-figure deals in mid-market and enterprise cybersecurity. Contribute to go-to-market strategies and build...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Grow your career with an innovative startup, driving strategic enterprise deals and cultivating key relationships with Fortune 1000 executives to showcase cutting-edge AI technology and deliver except...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$169K - $267K *

Lead the charge in driving innovative sales strategies across diverse industries, targeting a $32M+ annual sales goal. Collaborate with ecosystem partners to deliver AI-driven solutions that address c...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$150K - $200K *

The Sr. Sales Director is responsible for driving sales for our North American portfolio of solutions which include fulfillment, transportation, and payment solutions. Successful selling of complex fu...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Staffing

$160K - $180K *

Unlock potential by leading creative engagements across healthcare accounts. Drive innovative campaigns, mentor teams, and manage client relationships while delivering impactful narratives that resona...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $105K *

Transform creative visions into tangible assets by managing the entire production lifecycle. Oversee timelines, quality control, and vendor relationships to ensure projects are delivered on-brand, on...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$80K - $95K *

Grow your career by managing strategic accounts, driving revenue, and fostering long-term relationships. Leverage expertise in solution selling and account management to deliver customer-centric strat...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Champion growth by leading national accounts, driving strategy, and enhancing partnerships with specialty distributors and GPOs. Leverage expertise to ensure product availability and exceed corporate...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Unlock potential by leading a team of Business Analysts to drive strategic initiatives, enhance stakeholder engagement, and operationalize an embedded BA model, fostering growth and transformation wit...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$239K - $358K *

Join a team that's committed to maximizing growth in pharmaceutical accounts through strategic planning and relationship building, focusing on data-driven solutions and real-world evidence to foster l...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Contribute to impactful consulting services in government pricing, leveraging your expertise to guide clients through compliance, data analysis, and strategic initiatives while leading a collaborative...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $160K *

Manage and inspire a high-performing sales team to drive revenue growth and customer satisfaction within assigned accounts. Cultivate strategic relationships, oversee contract compliance, and develop...

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in expanding market presence by owning the full sales cycle, driving revenue growth, and translating complex financial technology into clear business value for SMEs across the US. Coll...

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.