Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$85K - $103K *

The Account Executive in-territory for Justworks in Dallas is responsible for managing the full sales cycle, from prospecting to closing deals, while building relationships within the small business c...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Lead the charge in driving complex sales within mid-market organizations, influencing hiring strategies and compliance. Own the full sales cycle, build strong pipelines, and engage with multiple stake...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Pioneer data-driven decision-making by analyzing operational metrics and financial performance. Collaborate with leadership to enhance efficiency and drive continuous improvement in a fast-paced manuf...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$222K - $278K *

Drive impactful change by consolidating technologies and digitizing workflows for enterprise customers, while fostering executive relationships and managing complex sales processes that promote safety...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $100K *

Elevate your sales career by building lasting client relationships and driving revenue growth. This role focuses on strategic account management, fostering connections, and leveraging a dedicated mark...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$90K *

Shape the future of dental technology sales by driving net-new revenue through strategic prospecting and complex negotiations with DSOs and group practices, focusing on competitive displacement and mu...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$350K *

Engage with key enterprise clients to drive revenue growth through strategic, solution-based sales. Develop lasting relationships and navigate complex sales processes while championing company values...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $200K *

Drive strategic revenue growth by engaging C-suite stakeholders and closing multimillion-dollar partnerships within large pharmaceutical organizations. Leverage your expertise to navigate complex sale...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$91K - $100K *

Join a team that's dedicated to managing mid and mass market accounts, enhancing customer relationships, and driving revenue growth through proactive solutions selling and collaboration with cross-fun...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Consumer Technology

$120K - $125K *

Lead the charge in mobilizing significant carbon transactions across Latin America, managing multi-stakeholder relationships and driving strategic initiatives to support forest protection programs und...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$85K - $95K *

Join a dynamic team to deliver exceptional client service, manage accounts, and enhance relationships with AmLaw firms. Drive success through proactive communication, issue resolution, and a client-fi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$120K - $175K *

Drive your career forward by leading new logo acquisition with AI/ML teams. Own the sales cycle, build consensus across stakeholders, and deliver accurate forecasting while connecting AI products to g...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $180K *

Contribute to the growth and satisfaction of enterprise clients by managing complex accounts, ensuring seamless execution and strategic alignment. Drive revenue growth and maintain relationships with...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Business Services

$91K - $138K *

Contribute to our growth by driving sales of SaaS solutions to government agencies. Collaborate with partners, build relationships, and exceed sales targets while navigating the complexities of govern...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$180K - $235K *

Drive growth by leveraging your consultative sales expertise to engage higher education leaders, aligning their needs with innovative research solutions while managing client relationships and achievi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$139K - $157K *

Elevate your career by leading transformative digital marketing strategies for high-profile clients. Drive measurable growth through innovative media plans and creative ideation while fostering truste...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$129K - $344K *

Empower your entrepreneurial spirit by launching and leading a local publication. Build partnerships, engage with the community, and drive revenue growth while enjoying the flexibility of a hybrid wor...

2 weeks ago

  •   Less than 5 years exp.  •   Staffing

$130K - $160K *

Accelerate your career by driving business development in the biotech sector. Build relationships, consult on data solutions, and enhance sales opportunities while collaborating with cross-functional...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Take ownership of complex institutional partnerships, driving customer success and retention. Collaborate cross-functionally to enhance account growth, manage contracts, and optimize platform implemen...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Elevate revenue growth by managing key accounts, driving new business opportunities, and implementing strategic sales initiatives to enhance customer relationships and profitability in the medical dev...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$150K - $235K *

Join a team that's redefining business processes through digital transformation. Lead cross-functional initiatives, ensuring scalable and standardized practices that align with strategic goals while f...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Champion new business development by identifying and converting revenue opportunities across enterprise customers and technology partners, driving growth and establishing long-term relationships in a...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $140K *

Champion growth by managing complex sales cycles and nurturing enterprise accounts. Collaborate with cross-functional teams to drive customer success and innovate solutions in the financial services s...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Transform your career by driving new business growth in enterprise accounts. Leverage your expertise in IT sales to identify key opportunities, build trusted relationships, and deliver strategic solut...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Lead the charge in expanding and retaining enterprise client relationships, driving revenue growth and strategic account management across regions. Develop and mentor a high-performing account team to...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.