Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$163K - $224K *

Drive strategic planning and execution of acquisitions/divestitures, ensuring seamless integration and value creation across teams. Collaborate cross-functionally to manage milestones, risks, and comm...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$67K - $104K *

Manage complex financial projects by collaborating with clients and vendors. Lead technical implementations, ensuring timely delivery and quality. Provide expert guidance and support throughout the pr...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Deliver exceptional client strategies and manage Meta campaigns to enhance performance and retention. Own client relationships, lead discussions, and optimize advertising efforts to drive results and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $190K *

Accelerate progress at senior living communities by leading a high-performing Customer Success team, ensuring measurable outcomes and fostering strong partnerships to enhance care delivery and custome...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Explore a pivotal role in shaping cloud infrastructure and DevOps practices. Lead initiatives to enhance software delivery, optimize processes, and mentor teams while ensuring compliance and security...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$170K - $190K *

Shape the future of data engineering by leading architectural improvements, enhancing data quality, and driving technical initiatives across diverse business domains. Collaborate with stakeholders to...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$155K - $195K *

Manage the transformation of Customer Support into a strategic function, driving operational efficiency and enhancing service quality. Lead a team to implement innovative strategies that elevate the c...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Champion global financial planning and forecasting processes, ensuring accuracy and consistency across regions. Collaborate with business leaders to enhance decision-making through insightful financia...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Business Services

$179K - $190K *

Shape the future of payroll and HR services by leading strategic initiatives, optimizing operations, and ensuring compliance across the employee lifecycle. Drive excellence in service delivery while f...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Healthcare

$77K - $95K *

Contribute to the development and support of data systems and applications, enabling data-driven decisions across the enterprise. Collaborate with teams to design scalable solutions and manage data in...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$170K - $190K *

Elevate student success by leading innovative marketing strategies for a nationwide education program. Drive engagement and growth through collaboration, creativity, and data-driven decision-making wh...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Advance healthcare solutions by driving sales of innovative diagnostic instruments. Engage with key stakeholders to promote QIAstat-Dx systems, ensuring successful adoption and customer satisfaction t...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $100K *

Unlock potential by driving treasury processes and cash forecasting for a multi-site organization. Collaborate with finance leadership to enhance liquidity management and support lender reporting, ens...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$160K - $190K *

Transform scientific vision into results by overseeing content development across therapeutic areas, managing client relationships and driving brand strategy for multiple accounts while fostering grow...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$100K - $120K *

Transform customer activation by leading operational readiness and training coordination. Manage a team to streamline onboarding processes and enhance productivity, ensuring customers reach their init...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Contribute to the growth of strategic opportunities by engaging key decision makers and driving early-stage specifications to influence net new business within targeted verticals. Collaborate effectiv...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Shape the future of insurance products by leading market analysis, financial strategy, and cross-functional collaboration to drive product development and implementation, ensuring alignment with enter...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$121K - $170K *

Drive your career forward as a strategic leader, guiding enterprise-level technology solutions. Engage with executive stakeholders, architect innovative multi-practice solutions, and influence digital...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$112K - $143K *

Drive new business growth and expand relationships in a designated territory. Manage broker and consultant channels, generate opportunities, and achieve revenue targets through strategic networking an...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $159K *

Lead the charge in transforming audience intelligence through innovative product strategies, enhancing consumer insights and data-driven solutions for brands and partners while ensuring privacy and co...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$155K - $175K *

Champion employee relations by leading a multi-site team, driving strategic oversight, and ensuring effective resolution of workplace issues while partnering with legal and HR functions to maintain co...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Transportation

$120K - $145K *

Transform the future of business applications by leading strategy, delivery, and operations. Collaborate with multidisciplinary teams to enhance core processes and drive value through effective system...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$95K - $130K *

Lead cross-functional IT projects, ensuring timely delivery and alignment with business goals. Manage project plans, risks, and stakeholder communication to drive successful outcomes and optimize reso...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Business Services

$175K - $210K *

Unlock potential by leading HEOR strategy and AI integration, ensuring project success and client satisfaction. Drive business growth, mentor teams, and influence health policy through innovative rese...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$84K - $105K *

Deliver exceptional client engagement by managing project success, assessing needs, and developing strategic plans. Lead cross-functional teams to ensure timely and budget-compliant implementations wh...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.