Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$127K - $223K *

Lead the charge in optimizing user journeys for engagement and retention. Design multi-channel re-engagement strategies for high-value client interactions, focusing on maximizing long-term value throu...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Join a team that's dedicated to enhancing employee experiences globally. Lead HR partnerships, support managers through change, and drive engagement initiatives while managing complex employee relatio...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $264K *

Unlock the potential of retail media by leading Ads Quality strategy for Sponsored Products. Collaborate with cross-functional teams to enhance customer and advertiser experiences, driving impactful i...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$90K - $110K *

Partner with us to design, build, and maintain data pipelines, ensuring reliable access to structured data for analytics, reporting, and emerging AI/ML applications across finance, HR, and operational...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $100K *

Shape the future of medical communications by crafting high-quality, scientifically accurate content. Collaborate with diverse teams to deliver impactful resources that meet client needs while mentori...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $225K *

Drive growth by identifying and closing enterprise accounts through strategic outreach and relationship building. Manage complex sales cycles and ensure seamless transitions for long-term customer suc...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Champion the development of AI-driven products, leading strategic initiatives and execution. Drive product roadmaps, manage budgets, and ensure alignment with business goals while delivering impactful...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$287K - $359K *

Drive growth as you cultivate federal accounts, enhance sales strategies, and facilitate large, strategic deals. Leverage your expertise to position mission-critical solutions in a competitive landsca...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$139K - $285K *

Drive the analytics engineering team to create AI-ready data solutions, ensuring trusted access to data across the organization. Lead strategic initiatives, build self-service capabilities, and foster...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$110K - $130K *

Shape the future of AI tools by collaborating with stakeholders to define requirements, prioritize opportunities, and guide delivery, ensuring alignment with business goals and user needs while managi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Staffing

$110K - $170K *

Pioneer innovative solutions in P&C insurance by owning the product roadmap for policy administration and commercial underwriting, integrating AI capabilities to enhance decision-making and streamline...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$146K - $225K *

Unlock potential by owning the operational health of technical accounts, driving integrations, and collaborating across teams to deliver exceptional service and solutions that align with merchant obje...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$190K - $220K *

Champion financial excellence by leading a dynamic team, driving strategic analysis, and leveraging AI to enhance decision-making for a diverse portfolio of clients in a fast-paced, remote environment...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Business Services

$150K - $180K *

Champion the growth of our commercial engine by leading business development efforts, forging strategic partnerships, and driving revenue as quantum computing transitions to enterprise applications. C...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $126K *

Join a team that's dedicated to enhancing client relationships and driving success through strategic SaaS solutions. You'll ensure satisfaction, maximize revenue, and foster growth within key accounts...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $150K *

Take ownership of a defined territory while collaborating with partner field teams in healthcare IT. Ensure successful sales integration by providing on-site support, training, and account strategy de...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Transform clinical trial management by overseeing site interactions, ensuring compliance, and mitigating risks. Collaborate with cross-functional teams to achieve project milestones while maintaining...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$130K - $228K *

Drive growth by leading strategic initiatives within the US Air Force, championing innovative data solutions to modernize operations and enhance mission success across defense programs while collabora...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$179K - $243K *

Lead the charge in driving growth for an OCIO investment solutions business by developing institutional relationships and winning complex mandates across diverse markets. Collaborate with key stakehol...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$143K - $225K *

Shape the future of federal policy by leading congressional engagement and driving funding strategies. Collaborate with executive leadership to translate technical capabilities into actionable priorit...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$68K - $136K *

Drive sustainable growth by managing key accounts and executing sales strategies in a collaborative environment. Leverage relationships and market insights to enhance customer engagement and achieve s...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$202K - $255K *

Lead a dynamic team of product marketers to shape the future of advertising strategies, ensuring seamless product launches and cohesive messaging that drives market leadership and enhances advertiser...

United StatesRemote

Reposted 2 days ago

  •   11 - 15 years exp.  •   Consumer Technology

$85K - $110K *

Empower clients by transforming their needs into innovative system designs. As a Design Engineer 2, you'll lead complex projects, collaborate with stakeholders, and refine your technical expertise whi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitality & Recreation

$170K - $190K *

Shape the future of client engagements by leading procurement relations, fostering trust, and unlocking growth opportunities through strategic partnerships that enhance collaboration and drive expansi...

RemoteRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$185K - $297K *

Lead the execution of innovative onboarding strategies, driving customer success through insights and support resolution. Collaborate with cross-functional teams to enhance product utilization and def...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.