Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$100K - $120K *

Shape the future of commercial sales by cultivating relationships with national accounts, driving revenue growth, and leading strategic initiatives to exceed market share goals while ensuring customer...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$140K - $170K *

Champion the future of customer engagement by leading lifecycle marketing strategies. Drive retention and loyalty through data-driven personalization across multiple channels, maximizing customer life...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Drive Beam's growth by securing partnerships and expanding market presence. Lead the sales cycle for Beam Notes, engaging key sectors and refining strategies to enhance product-market fit in the US. Y...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$195K - $245K *

Join a team that's redefining partner management by owning high-value relationships, driving growth through strategic planning, and collaborating across departments to enhance customer outcomes and re...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Elevate your career by leading the development of high-quality clinical documents for global regulatory submissions. Collaborate with cross-functional teams to ensure data-driven messaging aligns with...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$222K - $278K *

Reimagine enterprise sales by developing executive relationships and leading customer engagements. Drive revenue growth through strategic deal-making with a focus on customers while embodying core cul...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$187K - $257K *

Elevate global sales operations by leading forecasting, pipeline management, and productivity initiatives. Collaborate with sales leaders to enhance clarity and consistency, driving growth through inn...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$135K - $150K *

Accelerate progress at a leading firm by driving sales in the Tourism sector. Leverage your expertise to build client relationships, close deals, and collaborate cross-functionally, all while managing...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $215K *

Elevate growth at top global accounts by leading strategic sales initiatives, building executive relationships, and driving value-based solutions. Collaborate with cross-functional teams to achieve am...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$300K - $320K *

Elevate your career by mastering enterprise sales in a dynamic, supportive team. Engage with clients to showcase innovative solutions that address IT challenges, while exceeding sales goals and foster...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$132K - $170K *

Transform client relationships and drive growth by consulting with C-level executives to implement strategic solutions that enhance value and satisfaction across major accounts, ensuring retention and...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$250K - $300K *

Lead the charge in driving enterprise sales by collaborating with Microsoft teams to identify and capitalize on AVD opportunities. Leverage your expertise in VDI and EUC technologies to foster relatio...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$168K - $198K *

Champion regulatory excellence by guiding project teams, developing global strategies, managing submissions, and ensuring compliance with FDA and international regulations while navigating complex env...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $240K *

The Technical Strategy & Execution Lead will oversee the execution of client, research, and product initiatives, transforming abstract ideas into actionable roadmaps. This role requires leading high-s...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Lead a dynamic project management team to enhance client experiences through strategic execution, people management, and innovative workflows. Drive results while fostering a culture of excellence and...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$150K - $180K *

Transform the agent experience by leading strategy across recruitment, onboarding, and ongoing support. Drive engagement and success through cohesive learning and development initiatives, ensuring age...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$125K - $150K *

Lead and transform regional sales strategy across Asia-Pacific, driving growth through customer engagement, team development, and market expansion. Influence commercial outcomes while fostering strong...

6 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$135K - $150K *

Drive new business acquisition and revenue growth by proactively selling innovative FinTech solutions to enterprise clients, while managing complex sales cycles and building strategic relationships wi...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $172K *

Shape global procurement governance and compliance by leading analytics, training, and process excellence initiatives. Drive transformation and data management in a collaborative environment to enhanc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Pioneer transformative revenue operations by architecting scalable systems and AI-driven solutions across Sales, Marketing, and Customer Success. Lead a high-impact team to optimize processes and driv...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$180K - $220K *

Elevate your career by leading global marketing strategies that drive demand generation, enhance brand positioning, and support revenue growth in the healthcare technology sector. Collaborate with cro...

United StatesRemote

Reposted 6 days ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Join a team that's driving sales excellence in the Workday ecosystem. Leverage your expertise to build relationships, create strategies, and maximize ROI for clients while managing a large geographica...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Join us to drive strategic growth by identifying and securing new client partnerships while expanding opportunities within existing portfolios, focusing on the Grocery channel and collaborating across...

2 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$120K - $160K *

Drive strategic initiatives across partnerships, revenue, and operations. Collaborate with cross-functional leaders to tackle complex challenges in a fast-paced environment, ensuring effective executi...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $160K *

Champion strategic contracting excellence at a leading manufacturing site, overseeing customer and supplier agreements while ensuring compliance and operational efficiency in a regulated pharmaceutica...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.