Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$95K - $105K *

Collaborate with us to manage federal government contracts, ensuring compliance and effective execution throughout the contracting lifecycle. Support proposal development, contract administration, and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Staffing

$130K *

Shape the future of telecommunications by leading complex, large-scale projects. Drive strategic planning, manage executive communications, and ensure program success through innovative solutions and...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$125K - $150K *

Lead a dynamic sales team to drive growth in the oncology market. Foster relationships, develop strategies, and ensure execution of corporate initiatives while mentoring account managers and specialis...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $105K *

Elevate your career by managing the operational lifecycle of B2G products. Drive onboarding, renewals, and readiness activities while ensuring smooth day-to-day operations. Collaborate cross-functiona...

Iowa City, IARemote

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$170K - $190K *

Lead the charge in fostering dynamic relationships with strategic healthcare partners. This role requires navigating complex client ecosystems, influencing decisions, and driving collaborative innovat...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Drive operational excellence by leading revenue operations strategy, optimizing processes, and enhancing cross-functional alignment to support scalable growth and measurable outcomes in a dynamic envi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in defining and activating brand strategies across multiple channels, enhancing donor engagement and retention through innovative content and social communications while collaborating...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the charge in global quality strategy for high-speed interconnect solutions, driving operational excellence and customer satisfaction. Collaborate across teams to ensure top-tier product quality...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Elevate client success by crafting and optimizing innovative commerce media strategies. Leverage data-driven insights to enhance campaign performance across platforms, ensuring measurable growth and c...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$80K - $100K *

Accelerate business growth by owning the full sales cycle and expanding strategic partnerships with enterprise retailers. Leverage insights to consistently exceed revenue targets and drive impactful s...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Media

$79K - $170K *

Optimize global site activation processes to enhance efficiency and compliance. Collaborate with cross-functional teams to ensure timely project delivery while maintaining high-quality standards and f...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $140K *

Engage with Private Equity firms to develop strategic partnerships, promoting supply chain services and driving revenue growth through effective channel management and collaboration with stakeholders...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Transportation

$144K - $180K *

Transform public safety through strategic account leadership, driving sales for drone technology in major agencies. Own the full sales cycle, build deep relationships, and leverage AI tools to enhance...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$150K - $180K *

Join a team that's redefining data solutions by leading the Data Products & Engineering department, shaping cutting-edge data architectures and innovative client-facing analytics solutions that drive...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $170K *

Transform healthcare outcomes by leveraging analytics for smarter decision-making. Take ownership of custom analytics projects and productized engines while collaborating with cross-functional teams t...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$80K - $125K *

Engage partners and customers by driving product adoption and activation. Utilize your expertise to lead demonstrations, workshops, and co-selling efforts, ensuring users achieve meaningful results an...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Lead the charge in optimizing business processes and technology solutions, serving as the primary liaison between stakeholders and technical teams to enhance operational efficiency and customer experi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$130K - $160K *

Lead strategic banking initiatives by leveraging your enterprise sales expertise to build relationships and drive new business within Tier 1 global banks, shaping our go-to-market strategy and establi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$200K - $230K *

Unlock potential by leading a dynamic team in cloud services management, ensuring high availability and security while driving innovation through AI tools and fostering a DevOps culture for continuous...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$155K - $180K *

Drive successful delivery of complex, multi-year programs in a dynamic environment. Collaborate with cross-functional teams to manage scope, budget, and timelines while ensuring client satisfaction an...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Accelerate your career by leading innovative marketing strategies that drive lead generation and revenue growth. Collaborate with cross-functional teams to enhance brand visibility and cultivate a cul...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$415K - $435K *

Empower your career by leading regional Enterprise sales strategies to drive business growth and expand market presence. Manage high-performing teams and build relationships with C-suite executives to...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Join our dynamic team as a leader in delivering transformative AI solutions. You'll oversee enterprise-level projects, fostering relationships and driving growth while ensuring excellence in service d...

United StatesRemote

Reposted 2 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$142K - $168K *

Transform client experiences by leveraging deep expertise in healthcare solutions. Lead strategic initiatives, enhance client relationships, and drive impactful outcomes for high-value accounts throug...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$86K - $108K *

Optimize financial integrity as a Senior Accountant, managing general ledger functions, supporting month-end closes, and collaborating cross-functionally to ensure accurate reporting in a dynamic, hig...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.