Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$125K - $150K *

Drive your career forward by leading client engagement and market development in Knowledge & Research Services. Build relationships, shape client needs, and oversee impactful programs while collaborat...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$195K - $230K *

Drive growth by leading go-to-market strategies for TMC partnerships, building and executing plans from the ground up. Collaborate cross-functionally to influence product development and represent the...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$130K - $195K *

Drive enterprise sales success by engaging CIOs and CTOs, leading complex sales cycles, and connecting technology solutions to business outcomes. Leverage your expertise in cloud architecture and AI t...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$120K - $145K *

Lead the charge in developing high-performance, secure cloud components while collaborating with stakeholders to enhance data products and mentor junior engineers in an agile environment...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $125K *

Develop and execute strategies to enhance client engagement in the Military, Aerospace, and Government sectors, driving new business opportunities and managing key accounts to maximize value and foste...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $230K *

Accelerate growth by leading a high-performing sales team in the Professional Services & Consulting sector. Drive strategy, performance, and revenue while fostering a culture of collaboration and exce...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Consumer Technology

$162K - $243K *

Lead a dynamic team in managing complex clinical research trials, ensuring strategic execution and client satisfaction. Drive project success through effective communication, budget oversight, and qua...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$162K - $243K *

Lead a dynamic team in managing complex clinical research trials, ensuring project execution aligns with strategic objectives. Drive process improvements and maintain client relationships while overse...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$220K - $282K *

Champion enterprise growth by leading M&A, divestitures, and strategic partnerships. Drive evaluations, negotiations, and execution of complex transactions while advising senior leadership on strategi...

3 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$245K - $290K *

Champion strategic relationships in community oncology to enhance market access for innovative therapies. Drive account strategies, negotiate contracts, and collaborate cross-functionally to ensure op...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$144K - $184K *

Transform strategic accounts by driving sales and fostering executive relationships. Leverage deep industry knowledge to identify opportunities and enhance client satisfaction, ensuring growth and ret...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$185K - $226K *

Engage healthcare providers by promoting Copiktra, driving on-label sales growth through strategic territory planning and collaboration with cross-functional teams to meet customer needs and achieve s...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $145K *

Lead the charge in building and delivering data products that empower leadership and client engagements. This hands-on role requires strategic oversight and collaboration to ensure high-quality analyt...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Healthcare

$56K - $111K *

Drive success by cultivating strong relationships with clients to enhance satisfaction, retention, and sales growth. Collaborate with teams to deliver tailored solutions and insights, ensuring a seaml...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $135K *

Join a team that's shaping the future of data management by guiding strategic direction and execution for B2G registration and reporting platforms. Collaborate across technical and business domains to...

Iowa City, IARemote

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Lead multifamily transactions from sourcing to closing, ensuring disciplined execution and strategic alignment across teams. Drive outcomes through strong negotiation, relationship management, and a r...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$127K - $223K *

Transform the way we communicate life insurance through compelling copy that captures attention and drives action. Collaborate with teams to create impactful Direct Mail and social media content that...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Lead strategic sales initiatives across the Mid-West Territory, driving business growth through effective account management and relationship building. Collaborate cross-functionally to achieve sales...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $120K *

Drive revenue growth by selling mission-critical call handling solutions to public safety organizations. Build relationships, understand needs, and modernize 9-1-1 environments through consultative sa...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$200K - $300K *

Shape the finance and accounting infrastructure, ensuring accurate financials and compliance. Collaborate with teams to manage bordereaux data, oversee reinsurance accounting, and establish robust fin...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$113K - $164K *

Lead the charge in enhancing client success by strategically advising high-impact clients, fostering executive relationships, and driving solution adoption while mitigating risks and ensuring measurab...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Join a dynamic team to drive new business acquisition in a high-growth market. Leverage your expertise in full-cycle sales to build strategic partnerships and achieve uncapped earning potential while...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$90K - $110K *

Help us drive project success by managing AV integration projects from inception to completion, ensuring timely delivery, budget adherence, and client satisfaction while fostering collaboration within...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$91K - $110K *

The Account Executive in San Diego is responsible for managing the full sales cycle, including prospecting, building relationships, and closing deals. This role requires a proactive approach to expand...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$102K - $152K *

Transform the demand generation landscape by building effective lead processes, optimizing marketing operations, and enhancing campaign strategies. Collaborate with cross-functional teams to drive mea...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.