Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$164K - $305K *

Lead the charge in developing strategic relationships with C-suite executives to drive growth, retention, and value realization across complex health systems, ensuring integrated solutions and measura...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $150K *

Elevate client delivery by leading implementation teams, ensuring satisfaction and operational excellence across multiple projects while fostering strong relationships and driving continuous improveme...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$130K - $160K *

Reimagine business improvement strategies as a senior contributor, leading high-impact initiatives across functions. Drive alignment, governance, and measurable outcomes while influencing stakeholders...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Elevate your career by driving enterprise sales for innovative solutions. Engage with multinational accounts, build strategic relationships, and lead complex negotiations to unlock growth opportunitie...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$185K - $226K *

Champion the growth of Copiktra by engaging healthcare providers, executing strategic business plans, and driving on-label sales across your territory while collaborating with cross-functional teams t...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$205K - $256K *

Pioneer new customer acquisition strategies, focusing on major U.S. retailers. Lead negotiations and establish profitable relationships while managing the full sales cycle from pursuit to launch, ensu...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$120K - $140K *

Transform the sales landscape by driving growth in strategic accounts. Collaborate with leadership and cross-functional teams to develop a robust sales strategy for complex life sciences and medtech o...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $103K *

As an Account Executive in-territory in Miami, you will be responsible for managing the full sales cycle, including building and managing a sales pipeline, prospecting, and closing deals. This role re...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$340K *

Elevate your career by driving strategic sales in the TOLA region. Collaborate with cross-functional teams to build relationships, uncover opportunities, and deliver value through innovative SaaS solu...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Deliver strategic enterprise sales initiatives by driving new business, nurturing key client relationships, and leveraging technical resources to capture major accounts across North America and expand...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$240K - $300K *

Drive revenue growth by engaging top-tier law firms, cultivating relationships, and executing strategic sales initiatives. Collaborate with leadership to exceed sales targets and enhance market presen...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$82K - $108K *

Grow your career with a dynamic role driving strategic growth in wholesale and government sales. Lead account management, cultivate partnerships, and enhance market presence while collaborating cross...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Elevate your career by managing and optimizing multi-platform paid social campaigns. Leverage data-driven insights to enhance client ROI while collaborating with creative teams and leading strategic i...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Media

$160K - $200K *

Join a team that's redefining customer acquisition in the P&C insurance market. Drive strategic partnerships, enhance demand management, and support innovative solutions to elevate our marketplace to...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$225K - $265K *

Drive strategic partnerships in the East, building a robust pipeline and co-selling with AEs. Leverage deep relationships in security to enhance partner success and revenue, while traveling 40-50% to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$136K - $155K *

Champion integrated B2B marketing strategies by leading client relationships, driving account growth, and connecting marketing performance to business outcomes. Collaborate with cross-functional teams...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$114K - $186K *

Transform enterprise sales by guiding major organizations through their DevSecOps journey. Leverage your expertise to drive adoption and expansion of AI-powered solutions, ensuring long-term partnersh...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$130K - $195K *

Transform enterprise sales by engaging CIOs and CTOs, leading complex sales cycles, and connecting technology strategies to measurable business outcomes. Collaborate with cross-functional teams to dri...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$175K - $225K *

Drive strategic growth by enhancing partnerships within the senior living sector. Lead a team to optimize provider performance, boost retention, and elevate customer satisfaction, ensuring families ha...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $135K *

Unlock your potential by leading impactful projects from initiation to close. Collaborate with cross-functional teams, manage risks, and ensure timely delivery while utilizing AI tools to enhance prod...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$150K *

Help us build and optimize a centralized cloud data platform, driving enterprise strategy, governance, and analytics initiatives. Collaborative leader sought to transform data into a strategic asset a...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Media

$110K - $145K *

Elevate medical communications by developing high-quality, strategic content across therapeutic areas. Collaborate with teams and clients to ensure accuracy and adherence to guidelines while supervisi...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Pioneer growth in strategic enterprise accounts by navigating complex sales cycles, building consensus among security-focused stakeholders, and closing multi-year contracts in a competitive market. Dr...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$65K - $116K *

Drive exceptional client experiences by leading delivery operations, managing relationships, and leveraging analytics to identify service gaps. Collaborate cross-functionally to ensure seamless execut...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $110K *

Unlock potential by leading paid social strategies for top clients, driving performance and growth across platforms like Meta and LinkedIn. Manage a talented team while optimizing campaigns and enhanc...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.