Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$141K - $251K *

Champion enterprise data storage transformation by architecting complex subscription agreements. Collaborate with strategic leaders and engage C-suite executives to drive recurring revenue and redefin...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Empower regional marketing efforts by executing plans that engage key thought leaders and capitalize on local opportunities, driving success in hematology and oncology markets while collaborating with...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$136K - $160K *

Optimize account-based marketing strategies to drive engagement and sales for new products. Lead end-to-end campaign execution, asset production, and pipeline accountability while collaborating closel...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Unlock potential by driving complex sales into Fortune 2000 accounts, engaging with key stakeholders in compliance and technology. Shape the future of AI in enterprise solutions while achieving ambiti...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Innovate digital experiences by leading project execution across technology portfolios. Collaborate with business and tech leaders to drive priorities, enhance capabilities, and deliver exceptional me...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$250K - $300K *

Champion strategic growth by leading the charge to secure complex health system accounts. Drive transformative deals with hands-on coaching, leveraging deep relationships and expertise to elevate team...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$100K - $300K *

Unlock potential by driving enterprise growth in non-commercial foodservice technology. Own the full sales lifecycle, engage stakeholders, and deliver tailored solutions that enhance operational effic...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Join a team that's driving new business in the North American fleet market through high-volume outbound sales. Focus on pipeline creation and new logo acquisition while collaborating with Customer Suc...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$250K *

Grow your career with a strategic role focused on developing long-term partnerships with key industrial customers, enhancing relationships across multiple service lines, and driving revenue growth thr...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $150K *

Unlock the potential of strategic accounts as you build lasting relationships, drive retention, and identify growth opportunities. Be the primary advocate for our major enterprise clients, ensuring sa...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$190K - $250K *

Analyze and evaluate therapeutic opportunities to drive innovation and business development. Collaborate with interdisciplinary teams to assess scientific and commercial viability, ensuring alignment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $150K *

Join a team that's at the forefront of digital design as you lead strategic BIM operations across multiple disciplines. Drive collaboration, quality assurance, and innovation while mentoring teams to...

United StatesRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Technical Services

$80K - $120K *

Engage clients by driving sales of Managed and Professional Services, identifying opportunities, and delivering tailored solutions. Cultivate relationships to exceed revenue targets while leveraging i...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $250K *

Shape the future of global sales strategy by leading initiatives that drive partner growth and sales enablement. Collaborate with cross-functional teams to optimize processes, enhance capabilities, an...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$225K - $275K *

Lead the charge in redefining Total Rewards strategy, enhancing compensation, equity, and benefits to attract and retain top talent while anticipating workforce shifts driven by AI and market trends...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$105K - $120K *

Lead strategic partnerships by driving sales growth and managing complex relationships. Implement tailored sales strategies that adapt to market trends and partner needs, collaborating closely with se...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Information Technology

$180K - $225K *

Lead the architectural strategy and engineering evolution of Salesforce, managing a high-performing team while ensuring scalability, reliability, and security in revenue systems. Drive innovative solu...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$80K - $95K *

Elevate educational outcomes by driving new business and customer success in the TX territory. Build trusted relationships with decision-makers while delivering innovative literacy solutions to PreK–1...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Join a team that's dedicated to transforming literacy in PreK–12 education. Drive new business and foster long-term success by building relationships with key decision-makers and delivering impactful...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Champion growth by driving enterprise sales in cybersecurity. Collaborate with cross-functional teams to build strategies, manage complex sales cycles, and establish long-term partnerships with key st...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $140K *

Join a team that's driving project success by leading technical initiatives, resolving complex challenges, and aligning outcomes with client objectives. Your expertise will enhance profitability and o...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Engage with government agencies to drive revenue through strategic partnerships. Cultivate relationships, identify opportunities, and execute sales strategies to meet growth objectives in the Intellig...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Transportation

$80K - $95K *

Build strategic partnerships and drive growth in distribution channels across North America. Focus on relationship management, revenue growth, and channel enablement to enhance business performance an...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$125K - $150K *

Transform the creative landscape by leading innovative teams to deliver exceptional experiential campaigns. Drive strategic vision, inspire collaboration, and elevate brand experiences across diverse...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Media

$125K - $150K *

Optimize business growth by identifying new opportunities and building relationships with key stakeholders. Leverage solution-selling expertise to drive enterprise sales and achieve revenue targets wh...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.