Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
$103K - $181K *
Optimize document control processes by leading the Information Branch, ensuring accurate and accessible records management for a major industrial program while coordinating with various stakeholders a...
2 days ago
$88K - $154K *
Optimize document management processes for a large-scale industrial project, ensuring accurate, secure, and accessible records throughout all project phases. Collaborate with multidisciplinary teams t...
2 days ago
$110K - $130K *
Unlock potential by leading a global accounting team, driving process improvements, and integrating AI solutions to enhance financial operations and reporting accuracy in a dynamic SaaS environment...
2 days ago
Associate Director - Technology, AI, & Digital Solutions - Healthcare
$150K - $250K *
Transform healthcare technology engagements by leading multidisciplinary teams, developing actionable strategies, and implementing AI and automation solutions to enhance operational efficiency and cli...
2 days ago
$240K - $300K *
Transform patient care by providing comprehensive medical evaluations, diagnoses, and treatments. Collaborate with healthcare teams to enhance health education and ensure quality care while adhering t...
2 days ago
Wealth Advisory - Merger & Tuck-In Partnership Opportunities
$160K - $200K *
Grow your career with a leading RIA by transitioning your client base to a sophisticated platform. Leverage a collaborative team model to deliver comprehensive wealth management solutions for high-net...
2 days ago
Senior Implementation Consultant
$95K - $115K *
Lead the charge in implementing the Deacom ERP platform, driving customer success through expert consultation, project management, and tailored solutions. Collaborate with clients to enhance business...
2 days ago
Licensed Clinical Social Worker (Remote)
$78K - $92K *
Engage in impactful virtual counseling for patients with acute mental health conditions. Develop treatment plans, exercise clinical judgment, and collaborate with multidisciplinary teams to enhance be...
2 days ago
Clinical Psychologist (Remote)
$120K - $130K *
Shape the future of mental health care by providing virtual counseling and developing treatment plans for patients with acute conditions. Collaborate with medical professionals while ensuring adherenc...
2 days ago
$85K - $105K *
Transform client relationships by driving growth through consultative sales, managing complex opportunities, and collaborating with internal teams to exceed targets and deliver tailored solutions in a...
Reposted 2 days ago
$80K - $95K *
Transform the accounting function by overseeing monthly closes, ensuring compliance, and managing tax processes. Collaborate with finance leadership to drive accurate reporting and support strategic p...
2 days ago
$95K - $100K *
Transform virtual learning by leading strategy and development of innovative programs. Collaborate across teams to enhance educational experiences, ensuring quality and scalability while meeting diver...
2 days ago
Oracle OTM Solutions Architect
$125K - $140K *
Join a team that's dedicated to transforming supply chain solutions through innovative Oracle OTM and GTM implementations, ensuring timely delivery and optimal client satisfaction while enhancing your...
2 days ago
Senior Executive Director Finance
$121K - $145K *
Strategize financial operations and enhance reporting accuracy while leading the finance team. Collaborate with senior leadership to drive financial sustainability and operational efficiency across bu...
2 days ago
PMRT - Senior Software Engineer (Remote)
$140K - $160K *
Drive the development of critical enterprise applications for defense personnel, utilizing Java, Spring Boot, and Angular. Collaborate in an agile team to enhance program and financial management tool...
2 days ago
$121K - $155K *
Lead integrated campaigns and client relationships, driving strategy and execution across teams. Foster collaboration, optimize performance, and ensure client satisfaction while managing budgets and t...
2 days ago
Senior Director of Growth, Production & Capture
$160K - $200K *
Champion revenue growth by leading proposal operations and capture strategies. Drive compliance and execution across multiple concurrent pursuits while building scalable infrastructure to enhance mark...
2 days ago
$88K - $132K *
Help us drive growth as a strategic Channel Account Manager, collaborating with partners to create scalable sales strategies, enhance engagement, and achieve measurable outcomes in the enterprise tech...
2 days ago
Salesforce Technical Architect
$135K - $160K *
Lead the design and implementation of complex Salesforce solutions in a multi-org federal environment. Drive modernization efforts and ensure compliance while providing technical leadership and mentor...
2 days ago
$140K - $190K *
Champion growth by developing and executing strategic sales plans for tech-enabled services in the state and local government sector, driving client engagement and exceeding sales quotas through relat...
2 days ago
Principal Product Security Engineer
$229K - $258K *
Lead the charge in shaping product security strategy, driving cross-functional initiatives, and embedding security by design into engineering workflows. Collaborate with teams to enhance vulnerability...
2 days ago
Assistant Vice President OR Senior Underwriter - E&S Brokerage - Primary Casualty
$135K - $200K *
Drive profitable growth by underwriting middle market GL accounts in a non-admitted environment. Leverage strong broker relationships, evaluate risks, and mentor junior underwriters while ensuring com...
2 days ago
VP of Presales Solutions Architecture - AI Infrastructure
$175K - $210K *
Lead the technical strategy and pre-sales organization for AI infrastructure, driving complex enterprise deals and shaping product roadmaps through customer insights and architectural expertise...
2 days ago
$97K - $113K *
Lead financial operations and strategic planning for program teams, ensuring effective budget management, resource allocation, and compliance with regulations. Drive process improvements and enhance E...
2 days ago
Senior Project Manager - Health & Life Sciences Market Research (Remote, US-based only)
$85K - $110K *
Optimize project delivery by leading complex life sciences research initiatives, ensuring timely execution, quality standards, and effective vendor management while collaborating with cross-functional...
2 days ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.