Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
$120K - $145K *
Optimize your skills in developing and maintaining SAS programs within a Mainframe environment. Take charge of code migration to cloud technologies and engage with stakeholders to create analytical so...
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Director of Revenue Accounting & Assurance
$150K - $180K *
Advance your career by owning revenue accounting and assurance in a dynamic environment. Lead the development of policies, controls, and analytics while ensuring compliance with ASC 606 and preparing...
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$150K - $180K *
Join a team that's shaping the future of AI by designing and implementing enterprise-grade solutions on Google Cloud and Azure, focusing on data migration, pipeline development, and robust cloud infra...
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Senior Cyber Security Consultant
$110K - $130K *
Shape the future of cybersecurity in higher education by delivering expert assessments, advisory services, and tailored remediation plans that empower institutions to enhance their security posture an...
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$95K - $115K *
Join a team that's redefining power systems engineering by leading advanced studies in T&D, enhancing software tools, and fostering collaboration across projects to drive innovation and efficiency in...
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Senior Technical Program Manager, Infrastructure Programs
$130K - $170K *
Execute end-to-end digital onboarding of complex AI data center infrastructure, managing cross-functional teams to ensure timely delivery, stability, and optimization of high-performance systems for p...
Reposted today
Senior Principal Solutions Architect (Federal Civilian Growth)
$200K - $250K *
Join us in shaping technical strategies and growth initiatives for federal opportunities. Collaborate across teams to develop compelling solutions that drive success in complex pursuits, ensuring alig...
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Principal Systems Studies Engineer - Protection
$120K - $145K *
Innovate solutions in power systems engineering by leading consulting initiatives, enhancing client relationships, and driving strategic growth in protection and control services while ensuring high-q...
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Senior Java Software Engineer (Library of Congress)
$115K - $135K *
Lead the charge in developing high-quality software solutions, mentoring engineers, and driving process improvements. Collaborate with stakeholders to enhance systems and deliver impactful results in...
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Software Engineer III - Full Stack (Drupal)
$105K - $110K *
Drive innovation as a Software Engineer III, enhancing full-stack capabilities and mentoring junior developers while collaborating with stakeholders to improve engineering processes and deliver impact...
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Senior Operations Manager, Corrections
$100K - $120K *
Lead the charge in managing clinical operations for dialysis services, ensuring quality patient care, compliance, and operational efficiency across multiple facilities while fostering strong relations...
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Manager - Special Investigations Unit
$110K - $150K *
Lead the operations of a Special Investigations Unit, managing a team of investigators to enhance fraud detection and prevention. Drive compliance, collaborate with stakeholders, and shape strategies...
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Operations Excellence Director
$135K - $160K *
Accelerate operational excellence by leading continuous improvement initiatives across service organizations. Drive quality, safety, and efficiency while optimizing spare parts and enhancing service p...
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Assistant Director, Global Service Delivery
$100K - $120K *
Advance global service delivery by managing offshore partnerships, ensuring performance excellence, and driving operational improvements across teams to enhance productivity and quality outcomes...
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$80K - $95K *
Unlock insights by leading advanced data analytics for federal programs. Collaborate with cross-functional teams to ensure compliance and data integrity while mentoring junior analysts and presenting...
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$100K - $120K *
Lead EHS initiatives across multiple facilities, ensuring compliance and fostering a safety culture. Drive strategic planning, conduct inspections, and collaborate with teams to enhance environmental...
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Senior Manager, Care Escalations
$142K - $227K *
Unlock potential by leading the Escalations team to enhance customer resolution processes, drive quality outcomes, and collaborate across departments to address complex issues while fostering team gro...
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Principal Consultant - Power Energy Markets
$200K - $240K *
Advance expertise in energy markets by managing complex client engagements, developing strategic recommendations, and fostering client relationships. Utilize analytical skills to drive impactful solut...
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$103K - $181K *
Optimize document control processes by leading the Information Branch, ensuring accurate and accessible records management for a major industrial program while coordinating with various stakeholders a...
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$88K - $154K *
Optimize document management processes for a large-scale industrial project, ensuring accurate, secure, and accessible records throughout all project phases. Collaborate with multidisciplinary teams t...
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Sr. Director, Digital Marketing & Web Experience
$150K - $180K *
Innovate your career by leading digital marketing strategies and web experiences. Drive customer acquisition and revenue growth while managing a multidisciplinary team to enhance digital capabilities...
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$110K - $130K *
Unlock potential by leading a global accounting team, driving process improvements, and integrating AI solutions to enhance financial operations and reporting accuracy in a dynamic SaaS environment...
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Associate Director - Technology, AI, & Digital Solutions - Healthcare
$150K - $250K *
Transform healthcare technology engagements by leading multidisciplinary teams, developing actionable strategies, and implementing AI and automation solutions to enhance operational efficiency and cli...
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$240K - $300K *
Transform patient care by providing comprehensive medical evaluations, diagnoses, and treatments. Collaborate with healthcare teams to enhance health education and ensure quality care while adhering t...
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Wealth Advisory - Merger & Tuck-In Partnership Opportunities
$160K - $200K *
Grow your career with a leading RIA by transitioning your client base to a sophisticated platform. Leverage a collaborative team model to deliver comprehensive wealth management solutions for high-net...
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What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.