Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Strategic Accounts Program Manager - Remote
$110K - $130K *
Shape the future of data center projects by managing strategic client relationships, overseeing multi-million-dollar initiatives, and ensuring operational excellence throughout the project lifecycle...
3 weeks ago
$110K - $130K *
Unlock potential by leading analytics initiatives—crafting measurement frameworks, overseeing implementation, and mentoring a junior specialist to enhance client performance through data-driven decisi...
Reposted 3 weeks ago
$120K - $145K *
Grow your career with a dynamic team leading threat intelligence and detection engineering. Shape strategies to protect diverse industries from cyber threats, while building a high-impact program that...
3 weeks ago
Video Host & Producer - Remote US
$110K - $160K *
Pioneer engaging video content by presenting and producing high-quality, relatable explainer videos. Collaborate closely with content strategists to ensure videos resonate with viewers while enhancing...
Reposted 3 weeks ago
Senior Manager, Solution Engineering - DocV
$135K - $160K *
Drive customer success and system reliability by leading a high-impact, agile engineering team focused on short-term initiatives that enhance product adoption and solve complex integration challenges...
Reposted 3 weeks ago
Senior Intelligence Analyst, DPRK & China Focus
$120K - $145K *
Unlock the potential of crypto intelligence by owning in-depth analyses of DPRK and Chinese financial threats, tracing illicit networks, and producing actionable insights for stakeholders across the g...
Reposted 3 weeks ago
Sr. Director, Product Marketing & Content
$170K - $200K *
Drive impactful product marketing strategies that translate complex AI technology into compelling narratives. Shape go-to-market initiatives, create high-value content, and enable sales teams to effec...
3 weeks ago
$110K - $130K *
Unlock potential by engaging customers to develop tailored solutions using open-source technologies and cloud-native architecture. Drive success through collaboration and innovation, bridging engineer...
Reposted 3 weeks ago
$110K - $130K *
Champion customer success by acting as a proactive technical diagnostician. Drive account health through strategic insights and close collaboration across teams, ensuring seamless implementation and o...
Reposted 3 weeks ago
Senior Customer Engineer - LATAM
$110K - $130K *
Shape the future of analytics by serving as a trusted technical advisor, guiding prospects through data architecture and business outcomes while collaborating with sales teams to drive revenue growth...
3 weeks ago
$90K - $100K *
Join a team that's dedicated to enhancing data pipeline stability and server administration for enterprise analytics systems. Support the transition of legacy data models into Tableau while ensuring c...
3 weeks ago
$120K - $160K *
Advance HR technology by leading Workday administration, ensuring optimal system performance, security, and data governance. Collaborate with HR and IT to deliver solutions that enhance business proce...
3 weeks ago
$175K - $190K *
Join a team that's dedicated to providing strategic legal counsel on employment matters. Leverage your expertise to navigate complex issues, manage disputes, and develop scalable practices that align...
3 weeks ago
Partner Consultant, Accounting
$110K - $130K *
As a Partner Consultant at Ramp, you will establish and nurture relationships with Channel partners, providing expert demonstrations of Ramp's products and understanding customer needs. You will colla...
Reposted 3 weeks ago
Director, Medical Science Liaison (Dallas, AR, LA, OK, MS)
$236K - $259K *
Join a team that advances medical knowledge and relationships in lung cancer. As a key liaison, engage with healthcare professionals, support scientific initiatives, and collaborate cross-functionally...
Reposted 3 weeks ago
Senior/Staff Software Engineer, Network Infrastructure
$180K - $250K *
Join a dynamic team defining and optimizing robust networking infrastructure, ensuring fast, reliable, and secure connectivity across diverse environments including public cloud and private compute cl...
Reposted 3 weeks ago
Dealer Relationship Manager(MD/VA)
$90K - $100K *
Drive the success of auto lending customer service by fostering relationships, achieving sales targets, and enhancing client satisfaction in your designated area. Leverage your experience to promote p...
Reposted 3 weeks ago
Product Designer (Injective Labs)
$100K - $120K *
Deliver innovative design solutions for web products and DAPPs in DeFi. Collaborate cross-functionally to enhance user experience while managing diverse design projects and ensuring product quality th...
Reposted 3 weeks ago
$110K - $130K *
Unlock your potential by leading the strategic pricing and risk management efforts for homeowners and auto products. Drive profitable growth while ensuring compliance, leveraging cross-functional coll...
Reposted 3 weeks ago
Senior Product Marketing Manager
$120K - $145K *
Oversee go-to-market execution for diverse product suite, driving initiatives and sales enablement. Transition to 0-1 product ownership, guiding products from definition through launch, with a clear p...
Reposted 3 weeks ago
$120K - $160K *
Drive WellTheory's growth in benefits consulting by cultivating strong partnerships, educating consultants, and supporting client strategies. This hands-on, individual contributor role requires strate...
Reposted 3 weeks ago
Advertising Account Director, Mid-Market
$110K - $130K *
Shape the future of enterprise advertising by driving growth across a strategic portfolio. Engage with executive clients, reactivation of dormant accounts, and foster collaboration, leveraging your ex...
Reposted 3 weeks ago
Director, Governance, Risk & Compliance
$150K - $180K *
Optimize governance and risk management at scale, guiding compliance and security strategy while collaborating across teams to enhance our organizational resilience as we expand into new markets and n...
Reposted 3 weeks ago
Business Development & Capture - PubSec
$150K - $180K *
Drive the expansion of our impact in Federal, State, and Local agencies. Lead capture efforts for major program opportunities, collaborating with cross-functional teams to position our innovative data...
Reposted 3 weeks ago
$110K - $130K *
Pioneer innovative solutions by partnering with customers and teams to transform AI and HPC requirements into reliable deployments, driving success through technical depth and collaboration across fun...
Reposted 3 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.