Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Automation and Control Commissioning Manager
$150K - $200K *
Shape the future of large-scale data center projects by leading BMS/EPMS commissioning efforts. Drive operational excellence, manage onsite teams, and ensure quality standards are met across complex e...
2 weeks ago
Account Executive - Commercial VAST
$105K - $211K *
Unlock new business growth by engaging with senior executives and driving solutions that enhance collaboration. Thrive in a consultative sales environment while managing complex cycles and building lo...
2 weeks ago
$71K - $145K *
Transform small business lending by reviewing complex loan applications, providing insightful credit recommendations, and mentoring teammates to enhance decision-making processes while ensuring adhere...
2 weeks ago
Senior Manager, Business Development (Retail Media) - Capital One Ad Solutions (Remote)
$161K - $184K *
Elevate your career by driving strategic partnerships and revenue growth in a dynamic retail media environment. Leverage your expertise in sales and analytics to create tailored solutions that enhance...
2 weeks ago
Staff Full-stack Engineer - Shopping (Remote-eligible)
$244K - $279K *
Unlock potential by leading innovative solutions in cloud banking. Collaborate with experts to drive modernization, mentor peers, and optimize technology strategies across multiple projects, ensuring...
2 weeks ago
Full- stack Engineer 4 - Capital One Shopping Tech (Categories Team) (Remote - Eligible)
$179K - $204K *
Drive innovation by architecting and building scalable greenfield products, collaborating with cross-functional teams to transform consumer needs into impactful features while mentoring fellow enginee...
2 weeks ago
Senior Technical Account Manager, Life Sciences
$120K - $145K *
Partner with us to drive growth and customer engagement in the life sciences sector. Leverage your technical expertise and strategic insight to build trusted relationships and deliver analytics soluti...
2 weeks ago
Lead Piping Stress Engineer 1 - Nuclear
$118K - $180K *
Lead the charge in advanced piping engineering, providing technical direction and oversight for complex projects. Ensure compliance with industry codes while delivering high-quality solutions and fost...
2 weeks ago
Instrumentation & Controls Engineering Senior Consultant - Nuclear
$165K - $253K *
Join a dynamic team to lead complex instrumentation and controls engineering projects in nuclear power. Drive innovation, ensure compliance, and enhance safety through digital upgrades and strategic c...
2 weeks ago
Lead Instrumentation & Controls Engineer 2 - Nuclear
$134K - $205K *
Drive modernization of nuclear power plants by leading and supporting control projects, coordinating across disciplines, and ensuring technical execution to enhance operational efficiency and client s...
Reposted 2 weeks ago
$131K - $205K *
Engage in the design and evaluation of electric power generation projects. Provide technical support and owner’s engineering services, focusing on thermal power systems. Collaborate on project develop...
2 weeks ago
$120K - $170K *
Unlock potential by leading air quality projects and business development efforts. Drive innovative solutions for complex environmental challenges while mentoring teams and expanding client relationsh...
2 weeks ago
Director of Data Center Services
$125K - $150K *
Lead the charge in operational excellence for a Data Center Services unit, driving performance, workforce development, and customer satisfaction across multiple locations while overseeing mission-crit...
2 weeks ago
Manager, Learning & Development
$90K - $125K *
Champion employee growth by leading innovative learning initiatives and managing a dynamic L&D team. Drive strategy and execution of training programs that enhance skills, support career pathways, and...
2 weeks ago
Expert Decision Support Analyst
$100K - $120K *
Champion data-driven decision-making by transforming complex marketing insights into actionable recommendations. Collaborate with clients and teams to enhance reporting solutions and drive campaign su...
2 weeks ago
$83K - $100K *
Partner with us to save lives as a skilled pilot delivering critical care. You'll operate in diverse environments, contributing your expertise to life-saving missions while experiencing the thrill of...
Reposted 2 weeks ago
Senior Manager, Commercial Advanced Analytics
$148K - $222K *
Pioneer advanced analytics strategies to optimize omnichannel investments, translating global performance data into actionable insights. Collaborate with cross-functional teams to drive measurable com...
2 weeks ago
Professional (Senior) Sales Representative, Pain - Saint Louis W, MO
$100K - $162K *
Drive business growth by developing strategic plans and executing sales within your territory. Build strong relationships, achieve quarterly goals, and enhance your professional skills in a collaborat...
Reposted 2 weeks ago
Professional (Senior) Sales Representative, Pain - Des Moines, IA
$100K - $162K *
Join us to develop strategic sales plans, build relationships, and achieve goals in a dynamic territory. Drive success through effective presentations and continuous learning while adhering to ethical...
Reposted 2 weeks ago
Professional (Senior) Sales Representative, Pain - Kansas City E, KS
$100K - $162K *
Develop business strategies to achieve sales targets in the assigned territory. Build relationships with customers and peers while adhering to ethical sales practices. Play a key role in driving produ...
Reposted 2 weeks ago
Professional (Senior) Sales Representative, Pain - Omaha, NE
$100K - $162K *
Join a team that's committed to driving sales success through strategic territory management and effective relationship building with healthcare professionals, ensuring high productivity and ethical s...
Reposted 2 weeks ago
Sales Representative, Pain - Frisco, TX
$72K - $108K *
Drive success by developing strategic sales plans, fostering client relationships, and achieving targeted sales goals. Contribute to a high-performing team while adhering to ethical standards in the p...
Reposted 2 weeks ago
Professional (Senior) Sales Representative, Pain - Saint Louis S, MO
$100K - $162K *
Drive territory growth by developing strategic business plans and delivering tailored sales presentations to foster customer relationships while achieving sales targets and maintaining ethical standar...
Reposted 2 weeks ago
Professional (Senior) Sales Representative, Pain - Memphis S, TN
$100K - $162K *
Unlock potential by driving sales success in a defined territory, cultivating client relationships, and executing strategic plans to meet sales goals while adhering to ethical practices in the pharmac...
Reposted 2 weeks ago
Professional (Senior) Sales Representative, Pain - Saint Louis E, MO
$100K - $162K *
Transform your career through strategic sales initiatives in a dynamic healthcare environment. Achieve sales goals while developing strong relationships and maximizing territory potential. Join us in...
Reposted 2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.