Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
$140K - $270K *
Unlock potential by designing and deploying scalable AI systems that transform healthcare workflows. Collaborate with cross-functional teams to solve complex business challenges and drive measurable o...
2 weeks ago
Consumption Pricing Monetization Lead
$105K - $155K *
Unlock potential by leading the strategy for consumption-based pricing. Drive the execution of innovative pricing models and processes, collaborating with cross-functional teams to enhance customer ex...
2 weeks ago
Senior Operational Risk Manager
$179K - $249K *
Lead the charge in shaping and executing the Operational Risk program, collaborating with key teams to enhance risk management practices and reporting as the organization transitions to banking operat...
2 weeks ago
Field Sales Manager, Los Angeles
$90K - $120K *
Elevate brand presence through in-store execution, relationship-building, and training. Drive sales support and visual merchandising while collaborating with key accounts to enhance customer experienc...
2 weeks ago
Senior Manager, Database Platform
$242K - $275K *
Lead and elevate the Database Platform team, driving data architecture, reliability, and team culture for scalable data solutions. Collaborate cross-functionally to ensure data integrity and operation...
2 weeks ago
Manager, Support Engineering (AMER)
$115K - $194K *
Lead a dynamic Support Engineering team, enhancing customer experiences through AI-driven solutions, mentorship, and scalable processes while fostering a culture of growth and accountability...
2 weeks ago
Transportation Infrastructure PM - NEPA/PD&E
$125K - $225K *
Champion NEPA/PD&E projects by leading teams, managing budgets, and driving client relationships. Leverage extensive experience in highway/bridge sectors to deliver innovative solutions and ensure pro...
2 weeks ago
Senior Renewal Representative - HiEd
$80K - $95K *
Lead the charge in managing a complex portfolio of higher education accounts, focusing on strategic retention and growth. Collaborate with cross-functional teams to drive renewal success and identify...
2 weeks ago
Project Information Systems Administrator - Remote, US
$88K - $154K *
Unlock potential by administering project-level IT systems, managing access, ensuring data security, and coordinating with client IT teams to support project success and compliance across multiple ini...
2 weeks ago
Strategic Client Success Manager
$110K - $130K *
Empower customer success by managing strategic accounts, driving growth, and ensuring satisfaction. Build relationships, analyze data, and collaborate cross-functionally to exceed goals and mitigate r...
2 weeks ago
$150K - $195K *
Elevate client relationships by managing key accounts, driving satisfaction and growth. Collaborate with internal teams to deliver tailored solutions, ensuring long-term success and measurable ROI for...
2 weeks ago
Senior Product Marketing Manager
$176K - $327K *
Unlock potential by leading product marketing strategies for a cutting-edge data platform. Collaborate with cross-functional teams to create compelling content that simplifies complex technology, driv...
2 weeks ago
$150K - $180K *
Join a team that's redefining scientific data management in drug discovery. Lead the scientific data team, bridging scientists and engineers to ensure data integrity, quality, and innovative solutions...
2 weeks ago
$85K - $100K *
Join us to empower senior leaders by managing complex projects, client contracts, and travel arrangements. Your proactive support will enhance team efficiency in a fully virtual environment, fostering...
2 weeks ago
$110K - $130K *
Elevate client success by managing complex projects, ensuring timely delivery, and maintaining budget integrity. Collaborate with diverse teams to drive engagement and optimize project outcomes from i...
2 weeks ago
Lead, GTM Analytics & Applied AI
$190K - $210K *
Champion data-driven strategies by leading GTM analytics and applied AI initiatives. Collaborate with Sales or Marketing leadership to optimize performance, drive impactful insights, and build innovat...
2 weeks ago
Mainframe Systems Programmer - CICS & WAS
$65K - $123K *
Champion premium software support for mainframe clients, focusing on CICS and WAS. Drive installations, testing, and maintenance of systems software while ensuring timely customer service and effectiv...
2 weeks ago
$100K - $120K *
Join a dynamic team to enhance website performance and user experience through innovative SEO strategies, technical audits, and content optimization, driving organic visibility and business results on...
2 weeks ago
$80K - $95K *
Unlock the potential of fintech analytics by evaluating deal economics, monitoring profitability, and supporting forecasting across diverse financial verticals. Collaborate with cross-functional teams...
2 weeks ago
Service Project Manager - Mining and Materials
$79K - $127K *
Shape excellence by leading service project delivery and fostering customer satisfaction. This dynamic role demands robust management skills in the North American mining and material market, ensuring...
Reposted 2 weeks ago
$119K - $142K *
Join a team that's redefining digital operations by leading strategic initiatives, enhancing customer experiences, and driving growth in a fast-paced environment. Shape the future of MODAL Digital whi...
2 weeks ago
Financial Analyst - External Reporting
$107K - $147K *
Unlock potential by ensuring accurate and timely external financial reporting. Collaborate with cross-functional teams to enhance compliance and operational efficiency while driving continuous improve...
2 weeks ago
Senior Project Manager - Accela & Municipal Permitting Systems
$148K - $178K *
Transform municipal services by leading complex projects and optimizing the Accela Civic Platform. Drive innovation in permitting and development processes while ensuring compliance and enhancing cust...
2 weeks ago
Compliance Analyst II, Producer Oversight and Suitability Programs - Remote
$72K - $121K *
Join a team that's dedicated to promoting compliance while leading project initiatives. Collaborate across departments as a functional expert to establish policies and monitor compliance with regulato...
Reposted 2 weeks ago
$76K - $95K *
Join a team that's at the forefront of semiconductor technology, providing hands-on support and troubleshooting for advanced ZEISS systems. Collaborate with customers and teams to enhance service qual...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.