Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Senior Analyst of Transformation
$95K - $115K *
Join a team that's driving transformative change through strategic analysis and execution. This high-visibility role collaborates with leadership to ensure progress on critical initiatives and enhance...
Reposted 2 weeks ago
$80K - $95K *
Advance care quality by leading nursing services in Assisted Living and Memory Care. Foster a compassionate environment that empowers residents and supports team excellence, ensuring holistic, person...
2 weeks ago
$90K - $153K *
Engineer and deploy secure AI-driven applications and automation solutions, enhancing operational efficiency and collaboration across teams. Leverage Generative AI and cloud technologies to solve comp...
2 weeks ago
$100K - $120K *
Join a team that's redefining employee payment solutions. As an Implementation Manager, oversee the deployment of our SaaS product for diverse clients, ensuring successful integrations and fostering s...
Reposted 2 weeks ago
Senior Director, Client Success
$150K - $180K *
Reimagine client partnerships by managing complex relationships, driving performance, and leading recovery strategies. Collaborate with executives to ensure client success and identify growth opportun...
2 weeks ago
Director, Managed Markets - Regional - Central
$235K - $270K *
Drive your career forward by leading access strategies across the Central region. Manage key payer relationships and ensure launch readiness for rare disease products while collaborating with cross-fu...
2 weeks ago
Senior Manager, Strategic Bank Capital
$200K - $300K *
Join a dynamic team to manage bank capital relationships, drive coverage strategies, and support capital formation initiatives. This role offers growth opportunities in a fast-paced environment, focus...
2 weeks ago
Senior Instrumentation & Controls Engineer 1 - Nuclear
$84K - $129K *
Champion innovative solutions in instrumentation and control systems for power plants. Collaborate with engineers to design, troubleshoot, and enhance digital systems, ensuring project success and cli...
2 weeks ago
$110K - $130K *
Join a team that's redefining ERP solutions by analyzing complex business processes, developing custom architectures, and leading integration efforts to optimize performance and ensure compliance acro...
2 weeks ago
$110K - $130K *
Engage as a Legal Solutions Architect, bridging legal expertise and product strategy. Collaborate with Sales and Product teams to enhance legal workflows, drive product development, and empower legal...
2 weeks ago
Talent Acquisition Sourcing Specialist
$75K - $115K *
Unlock potential by sourcing top talent through innovative recruiting strategies. Engage with candidates, manage referrals, and support proposal efforts to build a robust talent pipeline for future op...
2 weeks ago
$128K - $250K *
Engage with clients to drive strategic account management and sales growth. Collaborate with cross-functional teams to develop proposals and ensure delivery excellence, while building strong relations...
2 weeks ago
$95K - $115K *
Elevate your career by leading regional health and safety initiatives, fostering a culture of safety excellence, and collaborating with stakeholders to implement effective safety management systems ac...
2 weeks ago
Senior Business Development Manager
$110K - $130K *
Join a team that's driving growth by sourcing and closing new business while nurturing existing accounts. You'll be the trusted operator ensuring client satisfaction and pipeline predictability, colla...
2 weeks ago
Senior Sales Compensation Analyst
$112K - $152K *
Join a team that's transforming sales compensation processes. In this role, you'll manage commission execution while collaborating on strategic plan design, ensuring alignment with company goals and d...
Reposted 2 weeks ago
Sr. Project Manager, Enterprise Transformation
$120K - $158K *
Unlock potential by leading complex, cross-functional technology projects. Manage project planning, execution, and stakeholder collaboration to drive successful outcomes in a fast-paced environment fo...
2 weeks ago
Territory Business Manager - Psychiatry - North & South Dakota
$125K - $155K *
Join a team that's driving sales success in the North & South Dakota territories. Leverage your expertise in pharmaceutical sales to educate healthcare providers and manage territory effectively, ensu...
2 weeks ago
Territory Business Manager - Psychiatry - North & South Dakota
$125K - $155K *
Elevate your career by driving sales and promoting innovative products in the North & South Dakota territories. Leverage your expertise to educate healthcare providers and manage territory effectively...
2 weeks ago
Assistant Superintendent- Special Projects
$80K - $95K *
Unlock your potential as a key player in our Special Projects Division, driving construction excellence through effective planning, communication, and safety compliance while managing project schedule...
2 weeks ago
$138K - $201K *
Architect cloud-based data solutions and drive enterprise data strategy. Leverage advanced analytics and modern data architectures to enhance operational efficiency and compliance in healthcare data m...
2 weeks ago
Healthcare Claims Payment Policy Managing Consultant
$113K - $188K *
Shape the future of healthcare reimbursement by developing and implementing payment policies that enhance accuracy, compliance, and provider experience in a dynamic payer environment. Collaborate with...
2 weeks ago
$140K - $168K *
Transform nursing operations across multiple skilled nursing facilities by providing clinical oversight, mentorship, and support. Collaborate with leadership to ensure high-quality care, regulatory co...
2 weeks ago
$160K - $200K *
Shape the future of financial strategy by leading teams in financial planning, analysis, and insights. Collaborate with executives to drive decision-making and optimize company performance through dat...
2 weeks ago
$110K - $130K *
Empower your career as a Platform Engineer, driving innovation in system architecture and cloud technologies. Collaborate with cross-functional teams to enhance platform efficiency and guide junior en...
2 weeks ago
Partnership Development Manager
$110K - $130K *
Transform partner relationships by driving revenue growth and ensuring strategic alignment. Collaborate with senior management to enhance partner experiences and optimize processes, while advocating f...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.