Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
Manager, Market Access & Reimbursement
$145K - $218K *
Architect innovative market access strategies to enhance U.S. reimbursement for cutting-edge healthcare solutions. Collaborate across functions to drive payer engagement, coding, and coverage initiati...
2 weeks ago
Clinical Applications Specialist, Contrast Media Delivery Solutions
$100K - $150K *
Join a team that's dedicated to enhancing clinical support through technical expertise and customer training. Drive product demonstrations and ensure customer satisfaction while collaborating with sal...
2 weeks ago
Imaging Field Service Engineer 1
$69K - $103K *
Join a dynamic team as you drive customer satisfaction through timely maintenance and support for advanced medical equipment, collaborating with experienced engineers to enhance your skills and contri...
2 weeks ago
$91K - $152K *
Join us to lead complex outage events in the power generation sector, ensuring safety, quality, and efficiency. Drive best practices and enhance operational excellence while managing teams and custome...
2 weeks ago
Lead Solutions Architect - DERMS
$103K - $154K *
Innovate and lead technical solutions for utility challenges, driving strategic growth through effective pre-sales engagement and deep collaboration with clients and internal teams to deliver tailored...
Reposted 2 weeks ago
Experienced Steam Turbine TFA (Nuclear)
$72K - $108K *
Partner with us to manage site activities, ensuring effective planning, resource integration, and compliance with contractual requirements in power generation facilities. Drive customer satisfaction a...
2 weeks ago
$114K - $190K *
Join a team that's driving the successful execution of complex Power Conversion projects, overseeing all phases from planning to closure. Ensure financial performance, quality, and customer satisfacti...
2 weeks ago
Sr Sales Manager 3 - Digital Solution Architecture
$108K - $181K *
Pioneer innovative solutions as a trusted advisor in Enterprise Asset Management. Engage with clients to enhance operational performance and ROI through Predictive Analytics while collaborating with c...
Reposted 2 weeks ago
Lead Commercial Proposals Manager-1
$92K - $154K *
Shape the future of energy by leading commercial strategies for Nuclear projects. Drive proposal development, manage risks, and ensure compliance while collaborating with cross-functional teams to del...
2 weeks ago
$71K - $115K *
Transform customer experiences by driving success and satisfaction through proactive engagement, relationship management, and strategic guidance. Collaborate with clients to maximize their use of Serv...
2 weeks ago
$100K *
Drive growth and strengthen relationships in Broker-Dealer and RIA channels. Consult with financial professionals on investment solutions, deliver market insights, and support business development ini...
2 weeks ago
Enterprise Account Executive- Midwest
$130K - $140K *
Champion growth by driving new revenue through strategic enterprise account management. Leverage your expertise to build relationships, maximize conversion rates, and close complex deals in a dynamic...
2 weeks ago
Manager, Strategic Partnerships
$71K - $90K *
Help us cultivate impactful donor relationships and enhance philanthropic support through strategic engagement and compelling communications, while collaborating across teams to drive major giving ini...
2 weeks ago
Account Manager- Smart Mfg & Industry 4.0
$80K - $95K *
Champion growth in smart manufacturing by managing key accounts, driving sales, and fostering relationships within the Industry 4.0 ecosystem. Leverage technical expertise to support IIoT adoption and...
2 weeks ago
Senior Manager, Project Controls, Project & Development Services
$148K - $175K *
Elevate your career by providing strategic oversight of project controls, balancing technical leadership with client advisory support. Mentor teams and influence delivery models while contributing to...
2 weeks ago
Principal, AI Transformation Lead
$154K - $193K *
Drive AI transformation by building client relationships, leading engagements, and delivering results. Own the sales process from prospecting to execution, ensuring successful integration of AI soluti...
Reposted 2 weeks ago
$113K - $170K *
Lead the charge in transforming customer integrations by driving technical discovery, scoping complex implementations, and ensuring successful onboarding for high-stakes accounts. Collaborate closely...
2 weeks ago
Senior Technical Product Manager
$141K - $177K *
Join us to shape the future of cybersecurity by leading product vision and strategy for our innovative Autonomous and Continuous pentesting platform, driving impactful solutions that enhance security...
2 weeks ago
Regional Sales Director (Chicago)
$112K - $143K *
Unlock new business growth by managing relationships and executing sales strategies across a designated territory. Drive market share expansion and achieve revenue targets through strategic networking...
2 weeks ago
Director, Neurology - Thought Leader Liaison (NORTHEAST)
$245K - $265K *
Build impactful partnerships with Medical Experts to enhance neurology care. Drive strategic insights and collaboration across teams, influencing marketing and education initiatives while engaging wit...
2 weeks ago
Staff Graphic Designer, Print & Packaging
$95K - $115K *
Elevate your career by leading innovative packaging design strategies that resonate globally. Collaborate with cross-functional teams to create compelling visuals while ensuring brand consistency and...
2 weeks ago
Medical Monitor (US Board-Certified Gastroenterologist)
$210K - $250K *
Innovate with us to enhance patient safety in global clinical studies. As a key medical expert, you'll provide critical input, oversee trial safety, and collaborate with teams to ensure compliance and...
2 weeks ago
Sales Manager, Strategic Accounts
$288K - $400K *
Inspire a high-performing sales team as you drive strategic growth, nurture talent, and foster customer relationships. Shape long-term sales strategies while managing daily operations to maximize reve...
Reposted 2 weeks ago
Stonehaven - Director of Ceded Reinsurance
$200K - $350K *
Unlock your potential as you structure and manage reinsurance programs, collaborating with cross-functional teams to ensure effective risk transfer and operational excellence in a dynamic environment...
2 weeks ago
Enterprise Account Executive - Healthcare Payors
$105K - $127K *
Champion growth by driving enterprise sales in healthcare payors, leveraging SaaS solutions to enhance client experiences. Build relationships, negotiate contracts, and exceed quotas while collaborati...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.