Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $119,100

Sort By: Relevance

$136K - $253K *

Shape competitive strategies by analyzing market trends and competitors. Drive insights for data and AI security, supporting diverse stakeholders globally. Own competitive messaging and tools to enhan...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$108K - $162K *

Transform regional marketing efforts by executing targeted programs that align with sales priorities and drive pipeline growth across the U.S. West territory. Collaborate with cross-functional teams t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$111K - $150K *

Elevate your career by leading innovative structural engineering solutions for utility-scale renewable energy projects. Collaborate with diverse teams to drive design excellence and mentor emerging ta...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Grow your career with a dynamic frontend engineering team focused on building robust platforms. Collaborate across teams to enhance product features, ensure high-quality deliverables, and drive innova...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $155K *

Join a team that's redefining energy solutions by designing innovative fluid and power systems. As a Process Engineer, you'll drive the development and optimization of cutting-edge technologies in a f...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$99K - $138K *

Transform dealer relationships in the Southeast by driving retail growth, onboarding partners, and serving as a trusted advisor. Collaborate cross-functionally to enhance dealer experiences and bring...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$200K - $250K *

Shape the future of enterprise solutions by bridging technical expertise and strategic vision. Collaborate with cross-functional teams to design impactful architectures that drive customer success and...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Empower your career by enhancing our platform's scalability and reliability. As a Senior Platform Engineer, you'll lead infrastructure improvements, optimize performance, and ensure security while col...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$205K - $285K *

Transform the on-premises CI/CD landscape by enhancing reliability, simplifying installations, and driving technical strategy. Collaborate with teams to build tools that empower engineers and ensure s...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$118K - $174K *

Take ownership of ERP solution architecture, driving strategic analysis and custom solutions while ensuring system integration, performance optimization, and compliance with regulatory standards to al...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $190K *

Empower your career by partnering with the Science Leadership Team to drive strategic initiatives, enhance operational effectiveness, and translate scientific vision into impactful outcomes across div...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $180K *

Lead the charge in driving agile execution across product and engineering teams, managing digital product launches and enhancing client value through innovative solutions. Collaborate cross-functional...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$121K - $191K *

Join the team to design and develop scalable software solutions for healthcare supply chain transactions. Collaborate with cross-functional partners to enhance the rules engine and deliver high-qualit...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the enhancement of Accubid Anywhere systems, ensuring data accuracy and workflow efficiency. Collaborate with teams to improve estimating practices and support project delivery, making a signific...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$95K - $105K *

Transform marketing and enrollment strategies for diverse educational institutions. Collaborate with senior leaders to diagnose challenges, develop actionable plans, and drive performance across the e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$141K - $166K *

Lead the charge in shaping product messaging and go-to-market strategies, driving awareness and adoption through cross-functional collaboration and strategic insights. This role demands a proactive in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $230K *

Elevate the sales strategy and operations by partnering with leadership to enhance productivity, implement AI solutions, and drive data-driven decision-making. Lead a team to optimize processes and en...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$135K - $159K *

Optimize client partnerships by driving strategic outreach and proposals. Leverage AI tools to enhance sales cycles, mentor peers, and contribute to revenue growth through long-term relationships and...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$140K - $223K *

Transform sales training and enablement by developing innovative strategies and AI tools to enhance agent performance, optimize customer interactions, and drive measurable improvements across direct-t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $193K *

Transform enterprise security by leading product strategy and delivery, focusing on data protection and compliance. Drive innovation through AI integration, ensuring scalable solutions that meet evolv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $170K *

Reimagine customer advocacy by building a robust reference program that connects customers to prospects and amplifies their voices, driving engagement and measurable business outcomes through collabor...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$170K - $200K *

Pioneer innovative solutions by leading client engagements with top firms. Drive discovery, connect needs to data insights, and collaborate across teams to deliver impactful results in a dynamic, remo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $225K *

Lead the charge in software development, driving innovation and collaboration across teams. Oversee strategic planning and team development to enhance product quality and efficiency, while fostering a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $121K *

Lead collections strategy for complex U.S. Enterprise accounts, ensuring timely payments while maintaining strong customer relationships. Collaborate with cross-functional teams to resolve issues and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$96K - $154K *

Develop and maintain quality software for internal stakeholders, focusing on Python and AWS. Collaborate in an Agile environment, define architecture, and mentor junior developers while enhancing lega...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.