Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Average Salary: $119,100
$108K - $135K *
Drive client success by managing a diverse portfolio, enhancing relationships, and implementing strategies for retention and growth. Utilize analytical insights to navigate complex client needs and fo...
1 week ago
$92K - $155K *
Unlock potential by partnering with leaders to drive talent strategies that align with business goals, enhance team performance, and foster a culture of growth and inclusivity in a fast-paced, innovat...
1 week ago
$110K - $130K *
Unlock potential by designing and managing Azure infrastructure, ensuring seamless hybrid connectivity and robust disaster recovery. Collaborate across teams to enhance operations, automate processes...
1 week ago
$80K - $95K *
Drive client success by managing relationships, optimizing collections, and resolving issues. Collaborate with diverse stakeholders to ensure satisfaction and compliance while leading a team to enhanc...
1 week ago
$80K - $95K *
Lead market expansion and provider relationships through consultative sales strategies, driving revenue growth and pipeline management within a dynamic healthcare environment while leveraging AI tools...
Reposted 1 week ago
Director, Technical Account Management
$160K - $200K *
Transform customer success by leading a technical account management team, driving subscription growth, and enhancing service delivery through innovative AI solutions and strategic partnerships...
1 week ago
$160K - $200K *
Shape strategic client partnerships and drive account growth while leading financial oversight and team development, ensuring exemplary service delivery aligned with commercial goals across global ope...
Reposted 1 week ago
Electrical Construction Superintendent
$100K - $120K *
Join our team to lead and supervise electrical construction projects, ensuring safety, efficiency, and quality. Drive growth in systems integration services while managing resources and fostering clie...
1 week ago
Senior ML Data Scientist - Women's Health
$172K - $203K *
Elevate women's health outcomes by developing advanced machine learning models. Lead projects, mentor junior team members, and collaborate with cross-functional teams to drive innovation and commercia...
1 week ago
Director, Business Development
$130K - $145K *
Drive growth by building strong partnerships with travel agencies, enhancing market share and brand awareness. Collaborate across teams to identify opportunities and execute strategies, making a signi...
1 week ago
General Manager, Venture & Private Equity
$275K - $325K *
Drive the venture and private equity business by owning strategy, partnerships, and P&L. Collaborate with teams to establish Flex as the primary financial institution in the sector, leveraging your ex...
1 week ago
Senior Employee Relations Business Partner
$81K - $122K *
Champion a positive employee relations environment by guiding, supporting, and resolving employee concerns. Collaborate with management and HR to ensure consistent and equitable practices that align w...
Reposted 1 week ago
Senior Sales Executive - Western U.S.
$110K - $130K *
Empower credit unions by driving new sales of digital banking solutions. Leverage your network to identify and close business opportunities, manage the full sales cycle, and exceed ambitious revenue t...
1 week ago
Principal Database Analyst (Ellsworth AFB)
$84K - $127K *
Manage and enhance database operations, ensuring security and performance. Collaborate with teams to develop innovative solutions and maintain integrity controls while contributing to policy formulati...
1 week ago
$175K - $210K *
Drive the go-to-market strategy for an AI-powered enterprise search platform, leading a high-performing sales team to achieve revenue goals while fostering strategic partnerships and aligning with pro...
1 week ago
$110K - $130K *
Empower your career by joining a dynamic Deal Desk team to support global sales. Drive deal execution and manage the end-to-end deal lifecycle, enhancing operational efficiency and collaborating acros...
Reposted 1 week ago
Senior Corporate Enterprise Platform Engineer, Windows
$159K - $215K *
Take ownership of Windows endpoint reliability and lifecycle management. Enhance provisioning, patching, and automation while collaborating with cross-functional teams to drive improvements and mentor...
1 week ago
Enterprise Account Executive - West
$130K - $140K *
Transform enterprise partnerships by leading complex sales cycles, aligning stakeholders, and driving impactful solutions for large educational organizations. Collaborate with executives to enhance op...
1 week ago
$95K - $115K *
Lead the charge in optimizing pricing processes, ensuring alignment across teams to drive strategic growth and enhance profitability while maintaining compliance and governance in pricing operations...
Reposted 1 week ago
$110K - $130K *
Grow your career with a dynamic team dedicated to providing advanced water treatment solutions. Leverage your technical sales expertise and relationship-building skills to drive revenue and foster str...
Reposted 1 week ago
$110K - $130K *
Innovate secure network solutions by engineering and supporting robust infrastructure. Collaborate with cross-functional teams to enhance security technologies, ensuring reliable connectivity and comp...
1 week ago
Territory Sales Manager - CCST (Colorado Springs, CO)
$108K - $135K *
Engage in driving sales success within primary care and specialty biopharmaceuticals. Collaborate effectively to execute strategic business plans, achieve sales goals, and launch new products in a dyn...
1 week ago
$180K - $220K *
Join a dynamic team to lead a growing golf company, driving strategy, product expansion, and financial performance. Own the P&L and collaborate with experts to innovate and scale, transforming the gol...
1 week ago
$125K - $145K *
Shape government funding strategies by partnering with sector leaders to identify and secure opportunities that align with research priorities, enhancing organizational impact through effective captur...
1 week ago
Brand and Marketing Creative Principal
$140K *
Pioneer a transformative creative vision by integrating brand storytelling with cutting-edge AI technology. Collaborate across teams to elevate marketing assets, ensuring every piece reflects our uniq...
1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.