Explore South Dakota Jobs Paying $100,000 or More

Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.

Find High-Paying Opportunities Across South Dakota

South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.

Explore South Dakota’s Major Job Markets

Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.

Build Your Next Career Move

Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.

Search South Dakota Jobs on Ladders

Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $121,112

Sort By: Relevance

$115K - $130K *

Lead the charge in scaling our TikTok Shop and Trybe Program, overseeing P&L, creator strategies, and LIVE commerce. Drive growth through strategic planning and community engagement, ensuring high-per...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$180K - $215K *

Lead regional launch initiatives, driving sales performance and team success through strategic execution and strong customer engagement in a fast-paced environment...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Innovate quantitative trading strategies by researching market behaviors, developing algorithms, and managing daily trading operations. Collaborate cross-functionally to enhance execution and optimize...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $164K *

Lead our cybersecurity and governance initiatives, enhancing security operations and risk management while driving compliance with CMMC 2.0 and ISO/IEC 27001 standards. Collaborate across teams to imp...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Unlock insights and drive performance as you analyze data, develop countermeasures, and execute strategies in the field. Collaborate with sales teams to enhance dealer activation and reduce churn, ens...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Drive partner success by providing expert technical guidance, leading complex implementations, and mentoring junior engineers. Collaborate cross-functionally to enhance product adoption and ensure opt...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$103K - $142K *

Transform workforce insights into actionable strategies by leveraging HR systems and analytics. Collaborate with cross-functional teams to enhance decision-making through compelling data visualization...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $150K *

Champion public safety operations across North America, leading program directors to ensure effective training, deployment, and customer satisfaction while aligning resources and operational prioritie...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$135K - $160K *

Shape the future of K-12 sales by leading a dynamic team of Account Executives. Drive performance through strategic planning, precise forecasting, and collaborative initiatives to achieve growth targe...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead the charge in transforming business needs into actionable data solutions. Collaborate with stakeholders to define requirements, prioritize backlogs, and deliver impactful data products that drive...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$144K - $200K *

Lead a national team of Key Account Leaders to drive sales in campus public safety, focusing on recruitment, coaching, and team performance. Shape strategies to enhance sales effectiveness and adapt t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$110K - $130K *

Transform your career by driving customer success and technical solutions. Collaborate with cross-functional teams to enhance client relationships, identify growth opportunities, and ensure maximum va...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$144K - $200K *

Lead the charge in developing a high-performing sales team focused on public safety. Drive recruitment, coaching, and retention while ensuring team success through strategic deal management and AI int...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$110K - $130K *

Transform your career by leading impactful field marketing initiatives across diverse brands. Collaborate with teams to create memorable events that enhance brand awareness and drive measurable growth...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$159K - $188K *

Unlock potential by leveraging data to drive product decisions and enhance user engagement. Collaborate across teams to design experiments, develop predictive models, and influence product strategies...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$279K - $349K *

Drive the strategy and execution of dedicated infrastructure engineering, leading a high-performing team to enhance enterprise SaaS offerings, ensure compliance, and deliver exceptional customer exper...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$157K - $283K *

Lead the charge in driving business growth by developing strategic partnerships and innovative solutions for federal clients, while collaborating with cross-functional teams to deliver exceptional res...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$180K - $200K *

Drive compliance excellence by leading regulatory strategy and governance, ensuring scalable infrastructure for service contracts and insurance programs across North America. Collaborate with executiv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Architect robust CI/CD pipelines and cloud infrastructure while driving innovation in geospatial science. Collaborate on AI architecture and ensure compliance-ready deployments across multi-cloud envi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$100K - $120K *

Manage and oversee retail banking construction programs, ensuring alignment with project goals. Collaborate with stakeholders, implement project management processes, and ensure compliance with qualit...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$100K - $120K *

Shape the future of healthcare by leading clinical operations across 3-5 skilled nursing facilities in eastern South Dakota, ensuring regulatory compliance and quality care while managing multiple tea...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$173K - $255K *

Elevate your career by defining and enforcing workload safety standards for a growing EKS fleet. Collaborate across teams to enhance availability and performance while mentoring engineers and driving...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Engineer and enhance the 1035YellowPages platform as a senior developer, responsible for full-stack development and client integration. Lead efforts in code ownership, debugging, and support while lev...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$217K - $303K *

Innovate the future of iOS development by architecting scalable solutions for Reddit's mobile app. Lead technical direction, mentor engineers, and enhance developer efficiency to support 100M+ DAUs wh...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$217K - $303K *

Empower your career by leading innovative solutions in a dynamic environment. Collaborate with cross-functional teams to enhance automated detection and enforcement strategies, driving impactful chang...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What South Dakota jobs on Ladders pay $100,000 or more?question toggle

    Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.

  • Which South Dakota cities have high-paying jobs?question toggle

    Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.

  • Are remote jobs available to South Dakota residents?question toggle

    Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.

  • How can I find senior-level jobs in South Dakota?question toggle

    Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.

  • Does Ladders verify South Dakota job listings?question toggle

    Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.