Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.
South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.
Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.
Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.
Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.
Average Salary: $121,112
$150K - $180K *
Lead a high-performance engineering team, driving strategy and innovation for Corporate Payments services while aligning technology with business goals. Foster collaboration and continuous improvement...
Reposted 1 week ago
Global BPO Partner Business Development
$167K - $366K *
Lead the charge in establishing strategic BPO partnerships globally, driving Zoom's disruptive CX platform into the outsourcing market. Own the full business development lifecycle, from prospecting to...
1 week ago
$76K - $186K *
Drive resolution for complex porting escalations, mentoring specialists and enhancing processes. Engage with high-value customers and partners, ensuring clear communication and effective management of...
1 week ago
Senior Treasury Solutions Consultant - Receivables
$96K - $207K *
Drive Treasury Management revenue by optimizing receivables solutions through collaboration with teams, leveraging technical expertise to enhance client cash application and working capital efficiency...
1 week ago
$108K - $122K *
Champion exceptional corporate events by leading strategy, design, and execution of high-impact experiences for clients and executives, ensuring alignment with business goals and delivering premium se...
1 week ago
$68K - $143K *
Analyze and reengineer business processes to enhance operational efficiency, collaborating with stakeholders to ensure alignment with strategic goals and regulatory requirements while supporting syste...
1 week ago
$68K - $143K *
Unlock innovative financial processes by driving transformation in logistics integration and optimizing resource allocation. Collaborate with diverse teams to enhance financial operations within the D...
Reposted 1 week ago
$82K - $172K *
Champion eDiscovery project management by leading high-visibility initiatives for the DOJ. Collaborate with legal teams to ensure seamless project execution across all EDRM phases, delivering quality...
1 week ago
Sr. Principal Pilot - USMC Aviation
$129K - $193K *
Join a dynamic team as a Subject Matter Expert, guiding mission planning solutions for USMC aviation. Collaborate with engineers and pilots to enhance operational capabilities and deliver impactful tr...
1 week ago
Business Development Director I, Early Drug Development
$80K - $120K *
Shape the future of Crop Protection & Chemicals by driving sales and fostering client relationships. Utilize strategic insights and collaboration to achieve targets and expand market presence while ma...
Reposted 1 week ago
Global Category Lead - Value & Access, Associate Director
$148K - $201K *
Drive category strategy and supplier relationships to enhance Market Access, Pricing, and Health Economics. Collaborate with cross-functional teams to optimize procurement processes and improve operat...
1 week ago
Sage Intacct Customer Support Senior Associate
$78K - $126K *
Grow your career with a leading professional services firm, providing expert support in Sage Intacct. Engage with clients, troubleshoot issues, and enhance your technical skills in a collaborative, re...
1 week ago
Clinical Lead - Senior Site Activation Lead
$116K *
Drive impactful site activation strategies, collaborating with cross-functional teams to ensure timely delivery of clinical projects while enhancing communication and mitigating risks throughout the p...
1 week ago
Clinical Lead - Site Activation Lead
$116K *
Lead site activation efforts by coordinating with cross-functional teams to ensure timely and quality delivery of clinical projects. Drive strategic initiatives and mitigate risks while enhancing comm...
1 week ago
Senior Director, Global Revenue Accounting and Order to Cash
$234K - $322K *
Transform global revenue accounting and order-to-cash processes in a dynamic healthcare environment. Lead a high-performing team, ensuring compliance with U.S. GAAP and driving systems improvements fo...
1 week ago
Strategic Advisory Services Consultant (Remote)
$95K - $140K *
Join a dynamic team to enhance cybersecurity programs, engage with clients, and deliver strategic advisory services. Contribute to thought leadership while developing tailored initiatives to protect o...
1 week ago
Incident Response Consultant (Remote)
$95K - $140K *
Empower organizations by leading incident response efforts, utilizing advanced forensic techniques to combat sophisticated cyber threats. Collaborate with a dynamic team to deliver impactful security...
1 week ago
Sr. Intelligence Analyst - DPRK Mission (Remote)
$85K - $120K *
Shape the future of cybersecurity by analyzing North Korean threats and providing actionable intelligence. Collaborate with experts to uncover insights that drive strategic decisions and enhance secur...
1 week ago
Sr. Construction Project Manager
$111K - $161K *
Transform the future of energy efficiency by leading a $200M facility upgrade project. Oversee construction, engage stakeholders, and ensure compliance with safety standards while managing resources a...
1 week ago
$92K - $134K *
Join us to lead the charge in managing a $32M facility upgrade project, ensuring effective collaboration with teams and stakeholders while maintaining safety and quality standards throughout the const...
1 week ago
Underwriter Personal Lines - III
$80K - $95K *
Transform your career by leveraging your underwriting expertise to mentor others, handle complex inquiries, and drive process improvements in personal lines insurance. Join a dynamic team dedicated to...
1 week ago
Senior Regulatory Affairs Associate - Regulatory Intelligence
$95K - $115K *
Drive regulatory intelligence initiatives to ensure compliance and support clinical research. Collaborate with experts to assess regulatory changes, track global guidelines, and enhance impact assessm...
1 week ago
Biotech Project Leadership - Clinical Trials - Home- Based
$110K - $130K *
Lead global clinical studies across diverse therapeutic areas, ensuring operational excellence and client satisfaction through effective project management and team leadership...
1 week ago
Environmental Consulting Project Director
$202K - $289K *
Champion growth in environmental services by leading business development, managing complex projects, and fostering client relationships in the power industry. Leverage your expertise to navigate regu...
1 week ago
Senior Transmission Line Engineer 1 - Grid
$84K - $129K *
Drive the design and development of high-voltage transmission lines, overseeing project teams and ensuring compliance with engineering standards while collaborating with clients and vendors to deliver...
1 week ago
What South Dakota jobs on Ladders pay $100,000 or more?
Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.
Which South Dakota cities have high-paying jobs?
Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.
Are remote jobs available to South Dakota residents?
Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.
How can I find senior-level jobs in South Dakota?
Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.
Does Ladders verify South Dakota job listings?
Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.