Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.
South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.
Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.
Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.
Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.
Average Salary: $121,112
$110K - $130K *
Drive growth by selling our innovative platform to financial institutions. Manage complex, multi-stakeholder sales cycles, guiding clients through their AI journey while exceeding annual quotas in a c...
1 week ago
Director, Community Safety Team
$172K - $216K *
Lead the Community Safety Team, driving public safety drone sales across diverse segments. Focus on recruiting, coaching leaders, and managing strategic partnerships while ensuring high integrity and...
1 week ago
Key Account Director, Majors East
$144K - $200K *
Accelerate public safety initiatives by leading a regional sales team, enhancing team performance, and driving strategic growth in drone technology for emergency response agencies across the U.S...
1 week ago
$170K - $250K *
Lead the charge in building high-throughput systems as you manage a team of engineers. Drive technical excellence and team growth while collaborating across functions to deliver innovative solutions i...
1 week ago
Director Sales II - Public Sector
$150K - $200K *
Drive sales excellence by leading a high-performing team in the SLED sector, focusing on strategic growth and customer satisfaction while managing a diverse product portfolio to achieve revenue target...
1 week ago
$150K - $180K *
Innovate with us to drive strategic product marketing initiatives that enhance capital equipment and consumable sales. Lead go-to-market strategies and foster market adoption, ensuring alignment with...
Reposted 1 week ago
$110K - $130K *
Shape the future of education by owning content strategy for assessments. Collaborate with experts and district leaders to enhance quality and drive adoption, leveraging insights to inform product dir...
1 week ago
EHR Application Principal Trainer
$67K - $100K *
Develop and deliver role-based training for EHR applications, ensuring curriculum accuracy and effectiveness. Collaborate with teams to optimize training environments and support user engagement in he...
1 week ago
Strategic Market Manager, North America
$110K - $130K *
Champion strategic marketing initiatives to drive growth in North America. Collaborate with cross-functional teams to develop market strategies, analyze trends, and enhance customer engagement, ensuri...
1 week ago
$120K - $145K *
Drive impactful change by optimizing product operations through collaborative process design, ensuring alignment and efficiency while fostering innovation and simplification across complex product tea...
Reposted 1 week ago
Senior Manager, Trust Services
$110K - $130K *
Unlock potential by leading a global team in Trust Services, enhancing client relationships, and driving operational excellence. Shape the future of AI-powered security solutions while ensuring top-ti...
1 week ago
Senior Advisor, Regulatory Starting Material
$153K - $268K *
Join a team that's advancing regulatory strategies for drug substance manufacturing. Lead the charge in selecting and justifying Regulatory Starting Materials, ensuring compliance with global guidelin...
Reposted 1 week ago
$120K - $170K *
Shape the future of enterprise infrastructure by leading design, implementation, and optimization of systems. Drive automation, enhance security, and mentor junior staff while collaborating on strateg...
1 week ago
Senior Director Business Development-West Coast
$200K - $225K *
Unlock growth by leading strategic partnerships in the CDMO sector. Drive sales, nurture client relationships, and collaborate across teams to enhance market presence and customer satisfaction. Your e...
1 week ago
Principal Account Executive, Americas Sales, Amazon Leo
$170K - $230K *
Join us to drive the adoption of innovative satellite services for enterprise customers. You'll manage complex deals, execute strategic initiatives, and collaborate cross-functionally to enhance custo...
1 week ago
EA-Account Executive, National Campaigns
$68K - $168K *
Transform political engagement by driving software sales within a designated U.S. territory. Build relationships with Democratic officials and campaign professionals while managing outreach and client...
1 week ago
$120K - $145K *
Lead the charge in shaping and expanding bridge design services across New England. Provide strategic direction, oversee project delivery, mentor staff, and strengthen client relationships to enhance...
1 week ago
Senior Associate, Investments & Fund Partnerships - Third Derivative
$84K - $103K *
Shape the future of startup financing by connecting innovative companies with vital capital solutions. Collaborate with founders and investors to develop tailored fundraising strategies and enhance th...
1 week ago
$160K - $175K *
Shape the strategic vision for data products, leading a high-performing team to drive data-informed decisions and enhance product strategy. Collaborate cross-functionally to establish data governance...
1 week ago
Enterprise Sales Account Executive
$110K - $130K *
Unlock potential by leading strategic account management initiatives, driving customer satisfaction and revenue growth through effective relationship building and expansion strategies in a dynamic ent...
1 week ago
$80K - $95K *
Transform airport advertising environments by conducting site visits, developing signage concepts, and collaborating with design teams. This role combines hands-on fieldwork with creative design to en...
1 week ago
Customer Success Manager, Enterprise - Central
$125K *
Transform customer experiences as a key advocate and technical partner, driving onboarding, adoption, and success for Enterprise clients while collaborating across teams to ensure optimal outcomes and...
1 week ago
Senior Corporate Counsel - Legal Transactions
$119K - $221K *
Support dynamic legal processes in tech sales by negotiating complex agreements. Collaborate with cross-functional teams, manage high volumes of transactions, and drive legal department initiatives wh...
Reposted 1 week ago
Senior Manager, Brand & Specialty Rx Contracts
$119K - $186K *
Lead the negotiation and administration of Branded & Specialty Rx contracts, ensuring alignment with business strategies and stakeholder interests. Collaborate with internal teams to optimize processe...
1 week ago
Oracle MFCS/Retail Merchandising lead
$120K - $145K *
Unlock potential by leading the Oracle MFCS merchandising workstream, driving design and delivery for a seamless omnichannel experience. Collaborate with teams to optimize processes and ensure success...
1 week ago
What South Dakota jobs on Ladders pay $100,000 or more?
Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.
Which South Dakota cities have high-paying jobs?
Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.
Are remote jobs available to South Dakota residents?
Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.
How can I find senior-level jobs in South Dakota?
Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.
Does Ladders verify South Dakota job listings?
Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.