Explore South Dakota Jobs Paying $100,000 or More

Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.

Find High-Paying Opportunities Across South Dakota

South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.

Explore South Dakota’s Major Job Markets

Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.

Build Your Next Career Move

Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.

Search South Dakota Jobs on Ladders

Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $121,112

Sort By: Relevance

$66K - $102K *

Lead the charge in delivering innovative SAP MDG solutions, leveraging your expertise to design, implement, and optimize data governance processes. Collaborate with cross-functional teams to drive imp...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$103K - $121K *

Champion project success by building pacing trackers and forecasting models, collaborating with Finance to enhance capacity planning and resource allocation, while providing leadership with real-time...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in shaping effective member communication strategies. Oversee product development to integrate robust data-driven solutions that enhance customer engagement and drive measurable busine...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$84K - $161K *

Lead the management of complex Personal and Advertising Injury Liability claims, ensuring timely resolution and strategic oversight. Collaborate with legal counsel and stakeholders to achieve optimal...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in executing North America's largest trade shows and events. Collaborate with sales and marketing teams to drive strategy, manage budgets, and enhance brand presence, while ensuring al...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Elevate your career by driving LPG tank sales across the Eastern US. Build lasting relationships with propane marketers and distributors while executing a results-driven commercial strategy to achieve...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$113K - $188K *

Champion the development of innovative tools for customer service teams, enhancing agent efficiency and service quality. Collaborate across departments to drive product strategy, leveraging data and u...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in transforming data analytics for critical enterprise systems. Drive innovative solutions, manage complex data architectures, and collaborate with diverse teams to enhance data-driven...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Elevate partner success by managing strategic mid-market and enterprise relationships. Drive revenue growth through effective onboarding, enablement, and co-selling, while collaborating cross-function...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $180K *

Join a team that's dedicated to delivering seamless technical solutions for clients. You'll scope, implement, and maintain risk screening and data integration workflows, ensuring optimal performance a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $115K *

Join a team that's redefining healthcare project management. Lead integrated initiatives, mentor talent, and drive excellence across diverse campaigns while fostering collaboration and innovation in a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $210K *

Advance our real estate strategy by leading portfolio planning, workplace design, and data analysis. Collaborate with internal teams and external partners to optimize office spaces, enhance employee e...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $120K *

Join a dynamic team to drive customer activation and retention strategies across the prescription lifecycle. Collaborate cross-functionally to optimize customer journeys and deliver measurable growth...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$225K - $265K *

Drive the development of seamless integrations for security platforms, leading a team to deliver high-quality, reliable products that enhance customer security stacks and ensure compatibility with evo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$115K - $162K *

Develop and optimize backend features for a Rust-based graph data service, enhancing reliability and scalability while collaborating across teams to deliver impactful solutions for GitLab's platform...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $200K *

Join us to drive AI integration by transforming client workflows into live agents. You'll manage the entire process from scoping to deployment, collaborating with teams to deliver impactful solutions...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Lead the future of asset-based field examinations by delivering insightful analyses, evaluating financial controls, and ensuring compliance. Collaborate with clients to assess collateral values and mi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $110K *

Shape the future of retirement planning by partnering with advisors to drive growth in employer-sponsored plans. Utilize your expertise to provide consultative sales support, foster relationships, and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$108K - $200K *

Champion the resolution of complex commercial casualty claims by delivering exceptional customer service, conducting thorough investigations, and collaborating with defense counsel to ensure fair outc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$160K - $200K *

Lead the charge in capital formation by raising equity from high-net-worth investors, ensuring timely funding for real estate deals. Build and coach a high-performing team while architecting a vibrant...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$57K - $145K *

Engage in critical electrical engineering tasks, focusing on operations and transmission planning. Collaborate on studies, compliance, and infrastructure projects to enhance regional electric systems...

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$80K - $95K *

Accelerate product launches by coordinating cross-functional teams, managing timelines, and ensuring compliance with quality standards. Drive the stage-gate process and maintain a unified project mana...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $120K *

Join a dynamic team to drive product strategy and execution for public safety software. Collaborate across functions to deliver mission-critical solutions that enhance community safety and support eme...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $200K *

Shape the future of data center networking as a Principal Technologist, leading complex pre-sales engagement and architecture for AI infrastructure. Collaborate with top industry players to innovate s...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$148K - $263K *

Manage and maintain Oracle databases, leveraging expertise in Unix scripting and PL/SQL. Engage in data migration, interface development, and automated task management while collaborating within a dyn...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What South Dakota jobs on Ladders pay $100,000 or more?question toggle

    Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.

  • Which South Dakota cities have high-paying jobs?question toggle

    Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.

  • Are remote jobs available to South Dakota residents?question toggle

    Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.

  • How can I find senior-level jobs in South Dakota?question toggle

    Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.

  • Does Ladders verify South Dakota job listings?question toggle

    Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.