Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.
South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.
Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.
Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.
Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.
Average Salary: $121,112
Senior Technical Business Developer – Grid Automation
$119K - $190K *
Drive your career forward by leading market expansion for our Grid Automation portfolio. Engage utility customers and partners, develop innovative solutions, and influence industry standards to propel...
Reposted 1 week ago
Contract Facilitator, Commercial/Market Access, Life Sciences Learning & Development
$100K - $120K *
Unlock potential by delivering impactful leadership and soft skills training for pharmaceutical and life sciences professionals. Engage diverse audiences, foster collaboration, and drive behavior chan...
1 week ago
Key Account Manager, Albertsons - Phoenix, AZ
$103K - $121K *
Join a dynamic team as you drive strategic account management, develop collaborative plans, and strengthen key business relationships with customers to achieve significant and measurable growth across...
Reposted 1 week ago
Claims Automotive Team Manager - Casualty
$80K - $95K *
Join a team that's dedicated to leading and enhancing Casualty claims operations. Oversee daily activities, provide coaching, and ensure compliance while fostering a culture of excellence in customer...
1 week ago
$95K - $110K *
Champion the growth of your sales career by sourcing leads, exceeding goals, and delivering exceptional customer service. Join a dynamic team that values ambition and offers comprehensive training for...
1 week ago
$87K - $116K *
Join a dynamic team to develop operational strategies and lead a branch, enhancing customer satisfaction and driving sales growth while training to manage diverse teams and projects effectively...
Reposted 1 week ago
Director Service Coordination and Long-Term Services and Supports, Geisinger Health Plan
$110K - $130K *
Join us to lead strategy and implementation for long-term services and supports, ensuring compliance and enhancing participant experience in a dynamic healthcare environment. Drive impactful partnersh...
1 week ago
Finance Partner Senior, Geisinger Health Plan (Eastern Standard Time Zone resident)
$95K - $115K *
Transform financial operations by providing strategic support to business units, leading forecasting, and enhancing financial performance through collaboration and mentorship. Drive initiatives that p...
1 week ago
Enterprise Terafina Delivery Analyst
$80K - $95K *
Champion the Terafina delivery process by coordinating initiatives across digital account management, ensuring effective communication, prioritization, and stakeholder engagement to drive operational...
1 week ago
Risk Operations Support Manager
$110K - $130K *
Join us to lead Model Risk Management governance activities, ensuring effective oversight and decision-making. Collaborate with stakeholders, manage projects, and enhance data quality while developing...
1 week ago
$115K - $135K *
Drive your career forward by managing a diverse portfolio of high-net-worth clients, delivering expert tax preparation and advisory services while collaborating with financial advisors to maximize cli...
1 week ago
Director of Public School Strategy – Scholarship Services
$160K - $175K *
Lead the charge in public school engagement strategy, fostering relationships with policy coalitions and district stakeholders to champion the federal tax credit scholarship program and enhance educat...
1 week ago
Senior Compliance Analyst (Compliance Oversight Activities) - Remote
$74K - $118K *
Elevate compliance standards by leading oversight initiatives, managing complex projects, and collaborating across teams to ensure regulatory adherence and effective governance in a dynamic environmen...
1 week ago
$120K - $145K *
Unlock potential by designing and implementing innovative knowledge graph solutions for healthcare data. Collaborate with cross-functional teams to translate complex requirements into scalable, produc...
1 week ago
$150K - $180K *
Develop and implement MLOps strategy for enterprise-grade ML systems, driving model lifecycle management. Collaborate with teams to design scalable pipelines and ensure high reliability across ML solu...
Reposted 1 week ago
Technical Architect - ML - GenAI
$150K - $180K *
Architect scalable Generative AI solutions using AWS tools, focusing on LLMs, RAG, and agent-based workflows. Collaborate with teams to ensure performance and cost efficiency while guiding implementat...
Reposted 1 week ago
Senior Litigation Attorney Workers' Compensation (Northern California)
$137K - $232K *
Manage complex workers' compensation cases, providing litigation services and strategic legal advice. Lead case handling from investigation to trial, ensuring optimal outcomes while mentoring support...
1 week ago
Sr. Staff Data Migration Engineer
$131K - $164K *
Drive transformative data migration initiatives by leading complex enterprise conversions, aligning cross-functional teams, and enhancing operational strategies to ensure successful onboarding and cus...
1 week ago
$80K - $95K *
Join our dynamic Account Management Team to drive growth in the corporate occupier software market. Leverage your sales expertise to build lasting client relationships and uncover new opportunities wh...
1 week ago
Intellectual Property & Contracts Paralegal
$81K - $139K *
Optimize your career by joining a dynamic Legal Team, supporting complex contracting and intellectual property matters while safeguarding proprietary technology in a fast-paced environment...
1 week ago
$150K - $180K *
Transform our brand narrative and market presence by leading strategic communications, driving influence, and building a high-performing marketing team that resonates with engineering leaders and elev...
1 week ago
$110K - $130K *
Lead and implement strategies to enhance account growth and customer satisfaction in the Automation Energy Industries Division, leveraging your expertise in industrial automation to achieve profitabil...
Reposted 1 week ago
Territory Manager | Central Coast
$90K - $180K *
Take ownership of market expansion by driving adoption of innovative medical solutions. Leverage your sales expertise to build relationships with healthcare professionals and capture market share with...
Reposted 1 week ago
Territory Manager | Portland, OR
$90K - $180K *
Join a team that's driving growth by expanding market share and adoption of innovative medical technology. This role focuses on strategic sales and relationship building within healthcare systems, ens...
Reposted 1 week ago
$80K - $95K *
Support clients by providing expert technical assistance and fostering strong relationships. Analyze software usage to enhance client success and drive retention through proactive engagement and colla...
Reposted 1 week ago
What South Dakota jobs on Ladders pay $100,000 or more?
Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.
Which South Dakota cities have high-paying jobs?
Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.
Are remote jobs available to South Dakota residents?
Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.
How can I find senior-level jobs in South Dakota?
Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.
Does Ladders verify South Dakota job listings?
Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.