Explore South Dakota Jobs Paying $100,000 or More

Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.

Find High-Paying Opportunities Across South Dakota

South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.

Explore South Dakota’s Major Job Markets

Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.

Build Your Next Career Move

Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.

Search South Dakota Jobs on Ladders

Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $121,112

Sort By: Relevance

$120K - $145K *

Drive the transformation of AI solutions by developing, deploying, and optimizing machine learning models. Collaborate with stakeholders to create innovative applications that enhance patient care whi...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Media

$109K - $173K *

Elevate your career by partnering with us to enhance financial forecasting and reporting processes. Leverage your analytical skills to improve business intelligence systems and drive key performance i...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $136K *

Transform fleet maintenance operations by leading strategic initiatives, optimizing performance, and ensuring compliance across multiple locations. Drive efficiency and reliability while fostering a c...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Transportation

$85K - $92K *

Join our team to enhance healthcare quality through precise coding audits, mentoring coders, and driving process improvements. Your expertise will help shape compliance and accuracy in outpatient serv...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$135K - $160K *

Champion cloud security excellence by engineering robust solutions across AWS and GCP. Drive vulnerability remediation, system hardening, and compliance for federal clients while mentoring junior engi...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Technical Services

$170K - $222K *

Drive strategic transformation initiatives across Product, GTM, and Operations. Lead cross-functional teams, manage complex portfolios, and deliver measurable results while fostering clarity and accou...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$168K - $219K *

Join a dynamic team as a Sr. Solutions Engineer, leveraging your expertise to solve complex business challenges for mid-market customers, driving impactful solutions and fostering collaboration to enh...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Shape the future of enrichment programs by driving strategy, execution, and operational excellence across multiple sites, ensuring impactful experiences for families and children while achieving finan...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$116K - $155K *

Shape the future of HR technology by leading strategy, governance, and optimization of HRIS. Drive operational excellence, enhance user experience, and ensure compliance while managing a high-performi...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$115K - $125K *

Drive the development and enhancement of enterprise planning solutions globally, focusing on Anaplan and supporting FP&A, Sales, and Production Planning initiatives. Collaborate with teams to analyze...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$150K - $180K *

Drive your career forward by leveraging advanced AI to enhance pricing programs. Join a new, dynamic team focused on building evaluations that ensure AI delivers value and accuracy, shaping the future...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Join a dynamic team to lead AI-driven pricing innovations in insurance. Shape strategies, evaluate models, and drive high-value applications to market. Your leadership will empower data scientists and...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$66K - $106K *

Help us ensure software quality by developing and executing automated test scripts, assisting in defect tracking, and supporting adherence to rigorous quality standards within an Agile environment...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $128K *

Elevate cybersecurity operations by monitoring threats, analyzing network traffic, and coordinating incident responses. Collaborate with teams to enhance security measures and mentor junior analysts w...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$66K - $106K *

Join a dynamic team to design and implement secure identity solutions using Okta, ensuring compliance with DoD standards while enhancing authentication processes across high-visibility systems in a fu...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$80K - $128K *

Elevate your career as a DFIR Analyst, conducting cyber data analytics, leading detection technologies, and enhancing security measures. Collaborate with IT teams to protect assets and support inciden...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$79K - $91K *

Transform healthcare delivery by leading the RN UM Team, ensuring timely care decisions and maintaining documentation quality while fostering a culture of clinical excellence and accountability...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$165K - $210K *

Transform retail sales strategies and lead a dynamic team to achieve revenue goals. Drive account management, develop talent, and collaborate with cross-functional teams to enhance product offerings a...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$108K - $135K *

Join our team as a Telehealth Pharmacist, where you'll enhance member health through Medication Therapy Management and clinical outreach programs, ensuring high-quality care and compliance with indust...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$94K - $179K *

Lead quality initiatives by optimizing test strategies and automation processes. Collaborate with cross-functional teams to ensure high-quality software delivery while mentoring engineers and driving...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$94K - $179K *

Lead the charge in managing complex projects from inception to completion, ensuring timely delivery and stakeholder satisfaction while guiding cross-functional teams through the project lifecycle...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$101K - $204K *

Help us shape compensation strategies that attract and retain top talent. As a Senior Compensation Partner, you'll collaborate with leaders to navigate complex compensation challenges and enhance our...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$92K - $158K *

Optimize security for AWS infrastructure by designing and implementing robust controls. Collaborate with teams to ensure compliance and continuous monitoring while addressing vulnerabilities and enhan...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$92K - $158K *

Lead the charge in cybersecurity compliance for an AWS-hosted Army application, managing vulnerability findings and security scanning while collaborating with technical teams to ensure robust security...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$120K - $145K *

Empower federal clients by architecting innovative ServiceNow solutions that enhance IT modernization. Lead design, integration, and release management while mentoring teams to deliver scalable, secur...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What South Dakota jobs on Ladders pay $100,000 or more?question toggle

    Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.

  • Which South Dakota cities have high-paying jobs?question toggle

    Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.

  • Are remote jobs available to South Dakota residents?question toggle

    Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.

  • How can I find senior-level jobs in South Dakota?question toggle

    Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.

  • Does Ladders verify South Dakota job listings?question toggle

    Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.