Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.
South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.
Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.
Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.
Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.
Average Salary: $121,112
$222K - $278K *
Join a dynamic team to drive enterprise sales, transforming industries through innovative technology. Engage with C-level executives, manage complex deals, and foster lasting relationships to enhance...
4 days ago
$100K - $300K *
Lead complex analytical initiatives by developing data solutions and dashboards that drive business insights. Collaborate with stakeholders to translate requirements into scalable analytical framework...
4 days ago
$190K - $220K *
Champion innovation and execution as you lead product management across diverse e-commerce channels. Drive strategic roadmaps, manage global teams, and deliver cutting-edge solutions that enhance cust...
4 days ago
$115K - $150K *
Innovate at the forefront of database management, ensuring performance, reliability, and security in a high-volume SQL Server environment. Lead incident response and engineering solutions to enhance o...
Reposted 4 days ago
Director, Executive Compensation
$156K - $227K *
Elevate executive compensation strategies by designing and leading Total Rewards programs that align with organizational goals, while collaborating with key stakeholders to ensure compliance and effec...
4 days ago
$120K - $160K *
Unlock potential by leading complex cyber investigations, mentoring junior analysts, and analyzing sophisticated threats to safeguard AI systems from misuse. Drive impactful decisions and enhance safe...
4 days ago
Manager, Industrial Controls Engineering
$144K - $211K *
Drive engineering excellence by leading a high-performing team in implementing and scaling industrial control systems. Collaborate across functions to ensure reliable, maintainable solutions that supp...
4 days ago
Commissioning Senior Project Manager
$120K - $160K *
Engineer the future of critical facility commissioning by leading project teams, managing schedules, and ensuring compliance with design and safety standards. Drive successful project execution throug...
4 days ago
SAP Business AI Lead Architect
$160K - $229K *
Lead the design and development of AI-driven solutions within SAP S/4HANA, integrating advanced AI technologies to drive business transformation and innovation across enterprise environments. Mentor t...
4 days ago
Account Manager, Client Development & Renewals (Texas)
$123K - $135K *
Engage with existing customer accounts to drive renewal retention and expansion revenue. This growth-focused role emphasizes consultative upselling and cross-selling, ensuring customer satisfaction wh...
4 days ago
Bioinformatics Application Scientist, NGS - AMER
$125K - $141K *
Join a team that's dedicated to providing expert bioinformatics support, bridging customer needs with innovative NGS solutions. You'll play a key role in pre- and post-sales activities, ensuring custo...
4 days ago
Senior Manager, Water Infrastructure
$180K - $200K *
Lead water infrastructure strategies, ensuring efficient design and compliance across data center projects. Collaborate with teams to secure agreements and manage risks, enhancing sustainability and c...
4 days ago
$110K - $130K *
Empower our engineering teams by leading technical recruitment efforts. Dive deep into candidate sourcing, build strong pipelines, and enhance the hiring process while ensuring a positive candidate ex...
4 days ago
Program Manager - AEC / MEP / Engineering
$130K - $160K *
Transform program execution by coordinating large-scale data center initiatives, ensuring alignment across stakeholders, managing risks, and driving milestones to successful completion while fostering...
4 days ago
Project Manager - AEC / MEP / Engineering
$90K - $130K *
Join a team that's driving large-scale infrastructure projects. As a Project Manager, you'll lead initiatives from kickoff to closeout, ensuring alignment with program objectives and stakeholder expec...
4 days ago
$90K - $117K *
Elevate your career by leading SDTM programming activities, ensuring quality deliverables, and collaborating cross-functionally to optimize clinical data transformation in a dynamic environment...
4 days ago
$128K - $250K *
Innovate enterprise sales by leading the strategy for large deal pursuits, engaging C-suite clients, and delivering transformative solutions in retail and logistics sectors...
Reposted 4 days ago
$125K - $145K *
Lead campaign strategy and execution for oncology pharma marketing, driving performance optimization and cross-functional collaboration. Own end-to-end campaign management, ensuring alignment with bus...
Reposted 4 days ago
$170K - $220K *
Lead the charge in providing comprehensive legal support for the CHVAC segment, collaborating with global teams to ensure compliance and address complex legal matters while driving strategic initiativ...
4 days ago
$135K - $160K *
Lead the charge in quality and validation readiness for complex programs, uniting Engineering, Product, and Customer Success teams. Utilize AI and automation to streamline processes, enhance delivery...
4 days ago
Account Executive, HME Provider Sales
$80K - $100K *
Join a team that's driving growth by acquiring new customers and enhancing revenue through innovative solutions. Manage the full sales cycle while collaborating with cross-functional teams to ensure e...
4 days ago
Revenue Enablement Program Manager II
$91K *
Champion cross-functional programs that drive strategic outcomes, ensuring alignment with organizational priorities. Lead complex initiatives, manage risks, and foster stakeholder engagement to delive...
4 days ago
Medical Director, Post Acute Care
$207K - $346K *
Lead the charge in evidence-based medical case reviews to ensure high-quality patient care while collaborating with a network of over 500 physician colleagues in a fully remote environment...
Reposted 4 days ago
Electrical Manager MV - 100% Travel
$100K - $120K *
Transform the future of utility-scale solar projects by leading electrical operations, ensuring quality installations, and fostering strong team collaboration while managing contractor activities and...
4 days ago
$91K - $115K *
Transform the candidate experience by sourcing top talent for sales and corporate roles. Collaborate with recruiters and hiring managers to build pipelines, utilizing advanced sourcing techniques and...
4 days ago
What South Dakota jobs on Ladders pay $100,000 or more?
Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.
Which South Dakota cities have high-paying jobs?
Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.
Are remote jobs available to South Dakota residents?
Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.
How can I find senior-level jobs in South Dakota?
Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.
Does Ladders verify South Dakota job listings?
Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.