Explore South Dakota Jobs Paying $100,000 or More

Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.

Find High-Paying Opportunities Across South Dakota

South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.

Explore South Dakota’s Major Job Markets

Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.

Build Your Next Career Move

Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.

Search South Dakota Jobs on Ladders

Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.

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1,000+

Jobs in South Dakota

Average Salary in USD

Average Salary: $119,100

Sort By: Relevance

$135K - $140K *

Advance your career by driving full-cycle recruitment for diverse Sales and Go-To-Market roles. Collaborate with leadership to attract top talent, enhance candidate experience, and optimize hiring pro...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$127K - $133K *

Elevate your career by managing vulnerability remediation in cloud environments. Collaborate with technical teams to analyze security risks, prioritize vulnerabilities, and implement effective solutio...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$170K - $190K *

Lead and innovate within UJET's Core Infrastructure team, focusing on cloud-native services. Shape strategies for scalable solutions that empower engineers and optimize the infrastructure for thousand...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $200K *

Transform regional performance by leading a high-performing sales team, driving market adoption, and executing strategic initiatives in the ophthalmic surgical industry to achieve commercial success a...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $200K *

Lead the national growth strategy in the Government & Military sectors, leveraging $2 trillion in annual spending. This pivotal role will establish Sonepar as the preferred partner in electrical distr...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$145K - $270K *

Elevate your career by leading global executive recruiting efforts, shaping talent strategies, and building high-performing teams. Drive impactful searches and foster relationships with senior leaders...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$72K - $97K *

Empower individuals by coordinating personalized care plans for seniors and members with disabilities. Collaborate with healthcare providers and manage caseloads while enjoying a flexible, remote work...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$350K - $400K *

Optimize enterprise sales growth by leading a high-performing team, refining strategies, and driving revenue. Collaborate across departments to enhance processes and ensure long-term success in a dyna...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$184K - $403K *

Lead the charge in shaping enterprise financial planning, guiding strategic decisions through insightful analyses and robust forecasting. Manage a high-performing team while driving accountability and...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Information Technology

$155K - $217K *

Join a dynamic team to negotiate and close high-profile commercial agreements, supporting various business units while driving growth in a leading SaaS company. Collaborate closely with sales and prod...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Manage project lifecycles from order to delivery, ensuring quality, budget, and customer satisfaction. Collaborate across teams to drive communication and resolve escalations while championing continu...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $160K *

Develop and execute strategies for deployment options across cloud and self-hosted setups, ensuring compliance and security. Collaborate with cross-functional teams to enhance product offerings and dr...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$84K - $124K *

Transform software solutions by designing, developing, and enhancing applications in an agile environment. Collaborate with teams to deliver high-quality, scalable systems while ensuring transparency...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$120K - $130K *

Manage strategic accounts within the Life Sciences sector, driving growth by cultivating customer relationships and identifying new business opportunities. Leverage industry knowledge to ensure alignm...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $130K *

Take ownership of sales within a key territory, identifying opportunities and nurturing relationships with clients to drive business growth and exceed sales goals through strategic engagement and effe...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Drive exceptional support experiences globally, leading a high-performing team to enhance operational efficiency and scale offerings as our customer base and product suite expand...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $130K *

Drive revenue growth by developing strategic sales plans and building client relationships in the dynamic Connected TV advertising landscape. Leverage industry knowledge to identify opportunities and...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $175K *

Join a dynamic team as you drive renewals and expansion for managed sales customers. Leverage executive relationships and strategic planning to enhance account growth while collaborating with cross-fu...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Media

$96K - $120K *

Champion the growth of SPINNING Systems by leveraging technical expertise, driving sales initiatives, and collaborating across teams to enhance customer engagement and market presence in the life scie...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$96K - $120K *

Pioneer growth and market penetration for advanced SPINNING Systems. Leverage technical expertise to support sales, engage customers, and collaborate cross-functionally, driving innovative solutions a...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $240K *

Develop innovative PCB layouts and improve product designs by collaborating with cross-functional teams. Ensure high quality and compliance throughout the engineering and manufacturing process, while...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$70K - $94K *

Elevate your career by leading innovative paid media initiatives, optimizing campaigns, and exploring emerging channels to enhance enrollment strategies. Collaborate cross-functionally to drive perfor...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$88K - $105K *

Join a team that accelerates growth in the Electric Utility sector by building robust relationships, driving sales strategies, and expanding market presence across multiple states. Ideal for motivated...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$162K - $185K *

Drive strategic product development to meet growth goals, prioritizing user impact and results while collaborating with cross-functional teams to deliver innovative solutions that resonate with both B...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Transform the cybersecurity landscape by driving revenue growth and building strong customer relationships in the mid-market segment. Leverage consultative selling and AI-driven solutions to engage te...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What South Dakota jobs on Ladders pay $100,000 or more?question toggle

    Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.

  • Which South Dakota cities have high-paying jobs?question toggle

    Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.

  • Are remote jobs available to South Dakota residents?question toggle

    Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.

  • How can I find senior-level jobs in South Dakota?question toggle

    Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.

  • Does Ladders verify South Dakota job listings?question toggle

    Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.