Explore Senior Machine Learning Engineer opportunities at companies building intelligent products and data-driven systems. These experienced professionals design, develop, and deploy machine learning solutions, turning research and business needs into reliable applications. Ladders features vetted professional jobs paying $100,000 or more, helping you find roles aligned with your skills and career goals.
Senior Machine Learning Engineers typically own substantial parts of the machine learning lifecycle, from defining problems and preparing data to training models, deploying services, and monitoring performance. They collaborate with data scientists, software engineers, product teams, and business stakeholders to deliver solutions that are accurate, scalable, maintainable, and useful.
Employers often seek strong programming skills, especially in Python, along with experience in machine learning frameworks, statistical methods, and software engineering practices. Familiarity with cloud platforms, distributed computing, MLOps, model evaluation, and production deployment can be valuable. Senior roles may also call for technical leadership, mentoring, and the ability to explain complex findings to cross-functional teams.
Senior Machine Learning Engineers work across industries such as technology, finance, healthcare, retail, and logistics. Depending on the organization, the role may focus on generative AI, recommendation systems, search, computer vision, natural language processing, forecasting, or fraud detection. Experienced engineers can grow into staff or principal engineering roles, technical management, or specialized AI leadership positions.
Search Senior Machine Learning Engineer jobs on Ladders to discover vetted professional opportunities with salaries of $100,000 or more. Compare roles by responsibilities, required expertise, and growth potential, then identify openings that match your experience in building and operating machine learning systems.
Senior Machine Learning Engineer, Ads Modeling
$148K - $244K *
Shape the future of personalized advertising by advancing innovative ML algorithms. Collaborate with cross-functional teams to enhance user experience and drive impactful results using large-scale dat...
Reposted 4 days ago
Senior Machine Learning Systems Engineer - Search
$150K - $180K *
Join a team that's at the forefront of machine learning and search innovation. Collaborate with cross-functional teams to develop scalable ML systems that enhance user experiences and drive impactful...
2 weeks ago
Senior Machine Learning Engineer, Agentic Systems (Active Secret Clearance)
$185K - $230K *
Unlock your potential as a Senior Machine Learning Engineer, driving innovative AI solutions and enhancing performance across complex workflows. Collaborate with diverse teams to shape the future of A...
3 weeks ago
Lead Machine Learning Engineer
$120K - $145K *
Lead the charge in machine learning solutions, guiding a team to create impactful models for life sciences clients, while shaping technical direction and mentoring engineers throughout the project lif...
4 weeks ago
Senior Machine Learning Engineer - Pricing
$202K - $224K *
Elevate your career by leading the design and deployment of advanced ML models and algorithms for large-scale systems, optimizing real-time marketplaces and driving significant business impact for mil...
Today
Senior Machine Learning Engineer, Advertiser Growth
$165K - $273K *
Transform the intersection of finance and technology by architecting advanced GenAI systems, ensuring reliable billing, and optimizing marketplace strategies to drive high-performance results and next...
Reposted 4 days ago
Senior Machine Learning Engineer, Advertiser Growth
$165K - $273K *
Optimize budget pacing and Creative GenAI systems. Support marketplace experimentation to enhance ad delivery while ensuring financial integrity through robust billing pipelines and precise analytics...
Reposted 4 days ago
Senior Machine Learning Engineer, Perception and Controls
$150K - $180K *
Transform healthcare by developing machine learning solutions for robotic systems. Collaborate with engineers and clinicians to enhance imaging and pose estimation, ensuring real-time performance and...
1 week ago
$140K - $192K *
Join a team that's pioneering advanced machine learning solutions, designing scalable data pipelines, and optimizing ad performance in a dynamic, remote-first environment. Collaborate with experts to...
2 weeks ago
$140K - $192K *
Design and implement scalable data pipelines and ML algorithms to optimize ad performance. Collaborate with cross-functional teams to tackle complex challenges in a dynamic, remote-first environment f...
2 weeks ago
$140K - $192K *
Optimize data-driven solutions by designing scalable ML pipelines and algorithms. Collaborate with cross-functional teams to enhance ad performance and tackle complex challenges in a fast-paced, remot...
2 weeks ago
$128K - $176K *
Unlock potential by joining our Data Science team to design scalable data pipelines and implement machine learning algorithms, tackling complex challenges in a collaborative, remote-first environment...
2 weeks ago
$128K - $176K *
Join a team that's tackling complex challenges in digital advertising by designing scalable data pipelines and implementing machine learning algorithms to optimize performance and efficiency in a fast...
2 weeks ago
$140K - $192K *
Transform complex data challenges into scalable solutions by designing real-time data pipelines and implementing machine learning algorithms. Collaborate with cross-functional teams to optimize ad per...
2 weeks ago
$128K - $176K *
Design and implement scalable data pipelines and machine learning models, collaborating with cross-functional teams to optimize ad performance and tackle complex data challenges in a fast-paced enviro...
2 weeks ago
$180K - $225K *
Unlock the potential of enterprise AI as a Senior AI/ML Engineer, leading strategy and architecture while hands-on building scalable solutions. Collaborate across teams to drive innovation and impleme...
3 weeks ago
$150K - $180K *
Discover and drive the future of healthcare leveraging unparalleled datasets. You'll lead end-to-end machine learning efforts, translating vast clinical data into actionable intelligence through innov...
Reposted 5 days ago
Senior Machine Learning Engineer, Government (IL5)
$200K - $260K *
Champion the deployment of Azure OpenAI within a DoD IL5 boundary, ensuring optimal performance and compliance. Lead efforts in model serving, pipeline migration, and evaluation to enhance AI capabili...
1 week ago
Senior Machine Learning Engineer, Government (IL5)
$200K - $260K *
Engineer cutting-edge ML systems within a DoD IL5 boundary, ensuring Azure OpenAI performs optimally. Collaborate on model deployment, evaluation, and secure data management while adhering to strict c...
1 week ago
Senior Machine Learning Platform Engineer — Model Hosting & MLOps
$147K - $230K *
Transform the ML landscape by building robust infrastructure for model hosting and MLOps. Collaborate across teams to ensure seamless deployment, monitoring, and management of custom models in product...
2 weeks ago
Principal Machine Learning Engineer
$160K - $200K *
Innovate large-scale ML systems, lead deployment, and ensure compliance with performance standards. Act as a trusted advisor, bridging customer needs and product capabilities while mentoring teams and...
6 days ago
Senior Machine Learning Engineer
$138K - $195K *
Unlock potential by designing and implementing advanced machine learning models that enhance advertising performance, collaborating across teams to drive impactful results for a global audience...
1 week ago
Senior Machine Learning Engineer, Premium Discovery
$140K - $252K *
Drive the evolution of Fable's recommendation systems by leading migration to Orion, enhancing real-time capabilities, and integrating social signals to improve user engagement and satisfaction across...
5 days ago
Senior Machine Learning Engineer, Premium Discovery
$170K - $265K *
Empower the future of reading by leading the migration of Fable's recommendation systems to a modern stack, enhancing user experience through innovative machine learning solutions and collaboration wi...
5 days ago
Senior Machine Learning Engineer, Premium Discovery
$140K - $252K *
Unlock your potential as a Senior Machine Learning Engineer, leading the migration of Fable's recommendations to a modern stack. Collaborate with a dedicated team to enhance user experience through in...
5 days ago
What does a Senior Machine Learning Engineer do?
A Senior Machine Learning Engineer builds and operates machine learning systems, including preparing data, developing and evaluating models, deploying them into production, and monitoring their performance. They often guide technical decisions and collaborate with product, data, and engineering teams.
What qualifications are commonly required for Senior Machine Learning Engineer jobs?
Requirements vary, but commonly include strong programming ability, machine learning and statistical knowledge, experience with production software, and familiarity with tools or frameworks used to train and deploy models. Senior positions may also require cloud, MLOps, system design, and mentorship experience.
What industries hire Senior Machine Learning Engineers?
Technology, finance, healthcare, retail, logistics, and many other sectors hire Senior Machine Learning Engineers to develop applications such as recommendations, fraud detection, forecasting, language technologies, and computer vision.
How can I find Senior Machine Learning Engineer jobs paying $100,000 or more?
Use Ladders to explore vetted professional openings with salaries of $100,000 or more. Review each listing's responsibilities, qualifications, and compensation details to find roles that fit your background and goals.