Explore Senior Machine Learning Engineer opportunities at companies building intelligent products and data-driven systems. These experienced professionals design, develop, and deploy machine learning solutions, turning research and business needs into reliable applications. Ladders features vetted professional jobs paying $100,000 or more, helping you find roles aligned with your skills and career goals.
Senior Machine Learning Engineers typically own substantial parts of the machine learning lifecycle, from defining problems and preparing data to training models, deploying services, and monitoring performance. They collaborate with data scientists, software engineers, product teams, and business stakeholders to deliver solutions that are accurate, scalable, maintainable, and useful.
Employers often seek strong programming skills, especially in Python, along with experience in machine learning frameworks, statistical methods, and software engineering practices. Familiarity with cloud platforms, distributed computing, MLOps, model evaluation, and production deployment can be valuable. Senior roles may also call for technical leadership, mentoring, and the ability to explain complex findings to cross-functional teams.
Senior Machine Learning Engineers work across industries such as technology, finance, healthcare, retail, and logistics. Depending on the organization, the role may focus on generative AI, recommendation systems, search, computer vision, natural language processing, forecasting, or fraud detection. Experienced engineers can grow into staff or principal engineering roles, technical management, or specialized AI leadership positions.
Search Senior Machine Learning Engineer jobs on Ladders to discover vetted professional opportunities with salaries of $100,000 or more. Compare roles by responsibilities, required expertise, and growth potential, then identify openings that match your experience in building and operating machine learning systems.
Machine Learning Scientist I / II, Protein Design
$176K - $304K *
Transform drug discovery as a machine learning scientist, designing advanced molecular solutions in collaboration with domain experts and AI teams to enhance biologics programs and establish robust ev...
Reposted 1 week ago
AI & Machine Learning Engineering Consultant - Manager - Consulting - Location OPEN
$150K - $251K *
Shape the future of AI solutions by leading innovative engineering projects across diverse client environments. Collaborate with multidisciplinary teams to build scalable, high-impact models and drive...
Reposted 2 weeks ago
Senior Staff Software Engineer, Knowledge Catalog For AI
$262K - $364K *
Shape the future of technology by leading innovative software solutions, driving architectural direction, and mentoring engineers. Collaborate across teams to enhance product capabilities and deliver...
Today
Senior Software Engineer (Backend) - AI/ML
$120K - $145K *
Unlock potential by designing and implementing AI-driven features across the full stack, creating scalable APIs, and enhancing user experiences within a collaborative environment focused on innovation...
3 weeks ago
$98K - $176K *
Architect cutting-edge AI and machine learning solutions to transform healthcare operations, leveraging modern tools, scalable models, and data accessibility. Drive impactful AI initiatives in a colla...
Reposted yesterday
Senior Product Manager, AI Operations
$150K - $200K *
Unlock potential by transforming workflows and enhancing team capabilities through AI. Collaborate across departments to implement innovative solutions that streamline operations and drive sustained a...
5 days ago
Lead Software Engineer, AI Platform
$164K - $240K *
Collaborate with cross-functional teams to build AI infrastructure, ensure reliability and security, and guide technical direction while fostering engineer development. Lead innovative projects that e...
Reposted 1 week ago
$132K - $221K *
Pioneer the development of autonomous AI agents and multi-agent systems, ensuring enterprise-grade standards in security, scalability, and performance. Collaborate across teams to innovate and optimiz...
1 week ago
Machine Learning Scientist/Engineer
$150K - $180K *
Join a team that's redefining robotics by developing foundation models for general-purpose robots. Collaborate on cutting-edge research, design scalable training methods, and contribute to real-world...
3 weeks ago
Senior Data Scientist (AI-assisted Clinical Development)
$142K - $264K *
Bring your expertise to drive AI/ML-powered digital solutions that transform medicine development. Collaborate across teams to build innovative tools, ensuring ethical impact and compliance in a regul...
Reposted 1 week ago
Senior Software Engineer, AI/ML, Search Personalization
$174K - $252K *
Pioneer innovative solutions in software development and machine learning, enhancing recommendation systems and architecture. Collaborate with teams to tackle complex challenges and improve user exper...
1 week ago
$130K - $155K *
Shape the future of security by designing workflows and response strategies. Collaborate with teams to strengthen our platform against complex attacks while engaging directly with customers to enhance...
Reposted 3 weeks ago
Applied AI Engineer (Full-Stack)
$125K - $150K *
Unlock innovative AI solutions by designing and building full-stack applications. Collaborate with teams to transform ideas into production-ready software, leveraging cutting-edge technologies and enh...
6 days ago
$300K - $350K *
Seeking a Developer Relations Engineer to enhance community engagement, improve user experience, and build tools for developers using ML models. You'll collaborate across teams, write code, and repres...
4 weeks ago
Research Engineer, Machine Learning, GeminiApp Personalization, DeepMind
$174K - $252K *
Transform user experiences by designing and building scalable personalization features. Collaborate with cross-functional teams to enhance AI capabilities and drive innovation in next-gen applications...
6 days ago
Robotic Process Engineer - Aerospace & Defense
$100K - $130K *
Accelerate progress at the forefront of robotic manufacturing by optimizing sheet metal forming processes. Engage in hands-on collaboration, utilizing CAD, data analysis, and cutting-edge robots to cr...
Reposted today
Robotic Process Engineer - Aerospace & Defense
$100K - $130K *
Join a dynamic team as you optimize robotic manufacturing processes for aerospace applications, collaborating with various teams to drive innovations and improve efficiencies in digital tooling and da...
Reposted today
Senior Platform Software Engineer - AI/ML & GPU Infrastructure
$167K - $245K *
Empower innovation in GPU infrastructure by architecting scalable control-plane services and scheduling systems. Collaborate across teams to enhance reliability and performance for AI workloads, drivi...
5 days ago
Research Scientist - Computer Graphics, Vision and Machine Learning
$125K - $150K *
Champion the advancement of visual storytelling through cutting-edge research and development in computer vision, machine learning, and computer graphics. Collaborate with teams to create innovative a...
3 weeks ago
$127K - $138K *
Innovate autonomous systems by developing algorithms for planning, scheduling, and resource allocation, leveraging AI technologies to enhance mission operations in space and beyond, while automating c...
Reposted 6 days ago
$135K - $170K *
Innovate data solutions that empower decision-making across teams. As a key member of the engineering team, you'll design and maintain data products, ensuring quality and accessibility for analytics a...
2 weeks ago
Machine Learning Engineer, Search - Local Services Team
$162K - $316K *
Drive innovation and enhance local service experiences by leveraging machine learning to refine search algorithms and recommendations for billions of users, improving conversion efficiency and user sa...
Reposted 3 weeks ago
Senior AI Enablement Software Engineer
$128K - $192K *
Unlock potential by designing AI tools and infrastructure that empower software teams. Collaborate across departments to enhance workflows and mentor peers in responsible AI practices, driving innovat...
1 week ago
Senior Applied AI/ML Scientist - Search Ranking
$211K - $290K *
Join a team that's at the forefront of AI-driven search innovation, transforming user experiences through advanced algorithms and machine learning techniques. Collaborate in a dynamic environment to d...
4 weeks ago
Lead Machine Learning Engineer - Agentic Pricing
$150K - $180K *
Transform the future of AI by designing and deploying LLM-powered agents on AWS and Azure. Collaborate with cross-functional teams to create production-ready solutions that enhance business operations...
2 weeks ago
What does a Senior Machine Learning Engineer do?
A Senior Machine Learning Engineer builds and operates machine learning systems, including preparing data, developing and evaluating models, deploying them into production, and monitoring their performance. They often guide technical decisions and collaborate with product, data, and engineering teams.
What qualifications are commonly required for Senior Machine Learning Engineer jobs?
Requirements vary, but commonly include strong programming ability, machine learning and statistical knowledge, experience with production software, and familiarity with tools or frameworks used to train and deploy models. Senior positions may also require cloud, MLOps, system design, and mentorship experience.
What industries hire Senior Machine Learning Engineers?
Technology, finance, healthcare, retail, logistics, and many other sectors hire Senior Machine Learning Engineers to develop applications such as recommendations, fraud detection, forecasting, language technologies, and computer vision.
How can I find Senior Machine Learning Engineer jobs paying $100,000 or more?
Use Ladders to explore vetted professional openings with salaries of $100,000 or more. Review each listing's responsibilities, qualifications, and compensation details to find roles that fit your background and goals.