Explore Senior Machine Learning Engineer opportunities at companies building intelligent products and data-driven systems. These experienced professionals design, develop, and deploy machine learning solutions, turning research and business needs into reliable applications. Ladders features vetted professional jobs paying $100,000 or more, helping you find roles aligned with your skills and career goals.
Senior Machine Learning Engineers typically own substantial parts of the machine learning lifecycle, from defining problems and preparing data to training models, deploying services, and monitoring performance. They collaborate with data scientists, software engineers, product teams, and business stakeholders to deliver solutions that are accurate, scalable, maintainable, and useful.
Employers often seek strong programming skills, especially in Python, along with experience in machine learning frameworks, statistical methods, and software engineering practices. Familiarity with cloud platforms, distributed computing, MLOps, model evaluation, and production deployment can be valuable. Senior roles may also call for technical leadership, mentoring, and the ability to explain complex findings to cross-functional teams.
Senior Machine Learning Engineers work across industries such as technology, finance, healthcare, retail, and logistics. Depending on the organization, the role may focus on generative AI, recommendation systems, search, computer vision, natural language processing, forecasting, or fraud detection. Experienced engineers can grow into staff or principal engineering roles, technical management, or specialized AI leadership positions.
Search Senior Machine Learning Engineer jobs on Ladders to discover vetted professional opportunities with salaries of $100,000 or more. Compare roles by responsibilities, required expertise, and growth potential, then identify openings that match your experience in building and operating machine learning systems.
Software Engineer - Learning Engineering and Data (LEaD) Program
$110K - $130K *
Empower cutting-edge solutions by designing, developing, and maintaining complex software systems with a focus on AI/ML applications in a collaborative and dynamic technology environment...
Reposted 2 weeks ago
Staff Machine Learning Engineer (Applied Modeling) - League of Legends
$150K - $180K *
Transform player experiences by developing and deploying machine learning systems that enhance personalization, improve matchmaking, and optimize in-game systems in a collaborative, innovative environ...
Reposted 1 week ago
$110K - $130K *
Join a team that designs and implements scalable machine learning solutions, collaborating with cross-functional teams to convert large datasets into actionable insights and drive digital transformati...
Reposted 3 weeks ago
Scientific Machine Learning Engineer
$130K - $160K *
Empower the future of drug discovery by designing scalable ML software that integrates with chemical physics workflows. Collaborate with scientists to enhance methodologies for predicting drug molecul...
3 weeks ago
Staff Test & Release Engineer, Inference Cloud
$135K - $160K *
Engineer robust test and release systems for cloud-based inference services. Collaborate across teams to ensure reliable, automated testing and deployment processes, enhancing software quality and del...
1 week ago
Senior Software/Robotics Engineer - State Estimation
$153K - $168K *
Champion the development of advanced state estimation systems, leading design reviews and ensuring high code quality. Collaborate with cross-functional teams to enhance aircraft navigation capabilitie...
1 week ago
Member of Technical Staff - Inference Infrastructure
$150K - $180K *
Unlock your potential by developing high-throughput inference systems, optimizing real-time processing, and enhancing reliability across diverse architectures within a collaborative, innovative enviro...
Reposted 3 weeks ago
Sr. Software Engineer - AI Platform
$188K - $235K *
Champion the future of AI by architecting and delivering innovative, scalable AI-native products. Lead the execution of core capabilities that transform technology landscapes, ensuring robust performa...
Today
Machine Learning Engineer - E-commerce Merchant Growth (LLM & Agentic Systems)
$162K - $387K *
Optimize and innovate ML-powered systems transforming merchant growth and e-commerce. Collaborate across teams to deploy actionable insights and predictive models that drive performance in a dynamic a...
Reposted 1 week ago
$180K - $250K *
Lead a dynamic team of machine learning engineers, driving innovation and mentorship while managing large-scale ML projects. Collaborate across departments to enhance product development and ensure qu...
Yesterday
$180K - $250K *
Lead the charge in expanding our machine learning team, mentoring engineers, and driving innovative projects. Collaborate across departments to enhance product development and ensure quality delivery...
Yesterday
Senior Software Engineer, AI/ML, Ads Retrieval and Resource Efficiency Optimization
$174K - $252K *
Join a team that's at the forefront of AI innovation, leveraging cutting-edge machine learning to enhance advertising technology and optimize user experiences on a global scale. Collaborate with exper...
2 weeks ago
$300K - $400K *
Join a dynamic team to optimize and scale production inference systems, ensuring reliability and efficiency for live traffic. Collaborate with research teams to implement cutting-edge techniques while...
3 weeks ago
$300K - $400K *
Drive the reliability and efficiency of production inference systems, ensuring seamless deployment and operation of cutting-edge models. Collaborate with research teams to enhance performance while ma...
3 weeks ago
Lead Machine Learning Engineer
$158K - $241K *
Tackle innovative challenges as a Lead Machine Learning Engineer, driving the development of cutting-edge computer vision and analytics solutions. Collaborate across teams, mentor junior engineers, an...
3 weeks ago
Lead Machine Learning Engineer
$158K - $241K *
Advance innovative computer vision solutions as a Lead Machine Learning Engineer, mentoring junior engineers and driving projects from concept to validation in a collaborative environment focused on d...
3 weeks ago
Technical Lead - Applied AI/ML Projects
$110K - $130K *
Elevate your career by leading AI projects that transform scientific applications. Drive technical direction, mentor engineers, and deliver innovative LLM solutions that improve real-world outcomes in...
4 weeks ago
Staff Software Engineer, IR Data Products
$216K - $239K *
Transform the future of Earth observation by leading architectural initiatives for scalable IR data systems. Drive cross-team collaboration and optimize low-latency processing while mentoring engineer...
3 weeks ago
Senior Software Engineer, AI Research
$154K - $227K *
Engage with cross-functional teams to design and optimize LLMs, tackling multimodal data at scale. Drive the full AI lifecycle from research to productization, enhancing performance on specialized har...
Yesterday
Senior Software Engineer - Autonomous Systems
$145K - $200K *
Drive the development of cutting-edge software for autonomous systems, integrating advanced sensors and AI to enhance mission capabilities. Collaborate with experts to redefine operational scenarios i...
2 weeks ago
Senior Data Scientist II, Ranking & Relevance
$183K - $216K *
Innovate the analytical roadmap for ranking and relevance, collaborating with cross-functional teams to enhance user engagement and advertiser outcomes while driving long-term platform economics and s...
1 week ago
$120K - $145K *
Transform autonomous systems through innovative AI/ML solutions, designing intelligent agents that optimize mission planning and execution across multi-domain environments while ensuring reliable perf...
Reposted 1 week ago
Machine Learning Engineer Graduate (TikTok-Data-Search-Recommendation) - 2027 Start
$128K - $256K *
Elevate the search experience by developing advanced algorithms and machine learning models. Collaborate with a dynamic team to create innovative solutions that enhance TikTok's search capabilities an...
Reposted today
$150K - $180K *
Lead the charge in delivering innovative AI solutions directly to clients, translating complex challenges into scalable systems. Collaborate with diverse teams and enhance customer operations through...
Reposted 3 weeks ago
$162K - $170K *
Drive advanced machine learning solutions as a key contributor to our perception team, focusing on deep learning and computer vision to enhance robotics technology and bring innovative models from ide...
Reposted 3 weeks ago
What does a Senior Machine Learning Engineer do?
A Senior Machine Learning Engineer builds and operates machine learning systems, including preparing data, developing and evaluating models, deploying them into production, and monitoring their performance. They often guide technical decisions and collaborate with product, data, and engineering teams.
What qualifications are commonly required for Senior Machine Learning Engineer jobs?
Requirements vary, but commonly include strong programming ability, machine learning and statistical knowledge, experience with production software, and familiarity with tools or frameworks used to train and deploy models. Senior positions may also require cloud, MLOps, system design, and mentorship experience.
What industries hire Senior Machine Learning Engineers?
Technology, finance, healthcare, retail, logistics, and many other sectors hire Senior Machine Learning Engineers to develop applications such as recommendations, fraud detection, forecasting, language technologies, and computer vision.
How can I find Senior Machine Learning Engineer jobs paying $100,000 or more?
Use Ladders to explore vetted professional openings with salaries of $100,000 or more. Review each listing's responsibilities, qualifications, and compensation details to find roles that fit your background and goals.