Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Senior Counsel Jobs in Missouri

Sort By: Relevance

$155K - $259K *

Shape the future of our captive and reinsurance business by leading actuarial strategies, optimizing structures, and delivering insights that drive profitable growth through collaboration and analytic...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$96K - $120K *

Empower businesses by providing tailored banking solutions, driving client engagement, and achieving sales goals. Collaborate with branch teams to enhance service offerings and foster strong relations...

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$132K - $176K *

Drive market growth by developing strategic partnerships and solutions. Collaborate with teams to enhance customer engagement and competitive positioning, ensuring alignment with long-term objectives...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$79K - $127K *

Partner with us to deliver comprehensive case management services, ensuring quality care and optimal health outcomes for members with complex needs. Collaborate with healthcare teams to develop and im...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$204K - $276K *

Unlock potential by leading Clinical Risk & Insights, driving systemic investigations and RCA methodologies to enhance clinical execution and decision-making across portfolios, ensuring sustained impr...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Champion the technical integration of partner ecosystems, ensuring seamless onboarding and operational reliability. Drive API discovery, documentation, and troubleshooting while collaborating with int...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$113K - $188K *

Optimize security administration and reporting processes while collaborating with cross-functional teams to enhance data insights and compliance metrics. Drive effective use of Workday tools and ensur...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Lead the charge in program management excellence, ensuring seamless operations and compliance across diverse teams while supporting critical Air Force contract initiatives and rapid-response readiness...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$170K - $230K *

Drive strategic growth and innovation in AI-enabled assessment and workforce solutions. Lead high-impact projects, foster collaboration, and enhance AIR's national leadership in education and workforc...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Join a team that's dedicated to driving financial excellence through detailed analysis, reporting, and strategic recommendations. Collaborate with leadership to enhance financial performance and suppo...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$94K - $164K *

Drive business continuity and disaster recovery initiatives, ensuring critical operations are sustained and services restored post-disruption. Collaborate with stakeholders to assess risks, validate r...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to matching healthcare providers with facilities, utilizing creative sourcing strategies and consultative skills to meet client needs while achieving personal productivity...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$102K - $152K *

Transform executive support by leading a dynamic team of EAs, enhancing processes, and driving strategic initiatives that align with company goals while fostering a collaborative culture...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Drive strategic permitting initiatives for complex energy projects, ensuring compliance with FERC regulations. Leverage your expertise to influence regulatory outcomes and support sustainable energy s...

Today

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Join us to drive impactful data analysis that enhances product performance and operational effectiveness. Collaborate with cross-functional teams to uncover insights, develop KPIs, and translate compl...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$165K - $185K *

Join a team that's shaping strategic direction and driving growth across multi-account projects in medical affairs. In this senior leadership role, you'll enhance client relationships, develop teams...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in developing client relationships and driving new business opportunities in the Life Sciences sector. Utilize a consultative sales approach to create bespoke marketing campaigns and m...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K *

Join a team that's driving impactful cross-functional initiatives by leading strategic delivery efforts. Leverage your project management expertise to align complex projects with enterprise priorities...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Engage in the design and management of enterprise endpoint technologies, ensuring security and efficiency across over 1,000 devices. Collaborate with cross-functional teams to enhance endpoint perform...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$88K - $105K *

Join a team that's dedicated to enhancing risk management and strengthening controls across the organization. As a Senior Internal Auditor, you'll lead audits, mentor junior staff, and influence key s...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate your project management career by leading a strategic platform within investor client coverage, enhancing client engagement and driving technology integration across CBRE's commercial real est...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$125K - $157K *

Shape the future of commercial banking by leading strategic implementations, optimizing client operations, and advising on best practices to enhance financial institution capabilities and drive long-t...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Lead the charge in overseeing a national Audit & Compliance team, ensuring regulatory adherence, risk management, and operational excellence while driving process improvements and fostering cross-func...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$200K - $225K *

Transform healthcare data into actionable insights by leading actuarial strategy and health economic analyses. Collaborate with cross-functional teams to enhance value propositions and drive commercia...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Drive client success as a key Account Manager, managing relationships across diverse industries. Oversee project lifecycles, enhance client experiences, and help shape the client services function fro...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.