Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
AVP & Actuary - Stop Loss Captives - Remote
$155K - $259K *
Shape the future of our captive and reinsurance business by leading actuarial strategies, optimizing structures, and delivering insights that drive profitable growth through collaboration and analytic...
6 days ago
$96K - $120K *
Empower businesses by providing tailored banking solutions, driving client engagement, and achieving sales goals. Collaborate with branch teams to enhance service offerings and foster strong relations...
5 days ago
Account Director Senior - Public Sector Business Development
$132K - $176K *
Drive market growth by developing strategic partnerships and solutions. Collaborate with teams to enhance customer engagement and competitive positioning, ensuring alignment with long-term objectives...
3 weeks ago
Senior Case Manager RN - Oncology (Remote)
$79K - $127K *
Partner with us to deliver comprehensive case management services, ensuring quality care and optimal health outcomes for members with complex needs. Collaborate with healthcare teams to develop and im...
3 weeks ago
Senior Director, Clinical Risk & Insights
$204K - $276K *
Unlock potential by leading Clinical Risk & Insights, driving systemic investigations and RCA methodologies to enhance clinical execution and decision-making across portfolios, ensuring sustained impr...
Yesterday
Senior Technical Program Manager, Partner Ecosystem
$125K - $150K *
Champion the technical integration of partner ecosystems, ensuring seamless onboarding and operational reliability. Drive API discovery, documentation, and troubleshooting while collaborating with int...
Yesterday
Lead Analyst, People Analytics
$113K - $188K *
Optimize security administration and reporting processes while collaborating with cross-functional teams to enhance data insights and compliance metrics. Drive effective use of Workday tools and ensur...
6 days ago
$80K - $95K *
Lead the charge in program management excellence, ensuring seamless operations and compliance across diverse teams while supporting critical Air Force contract initiatives and rapid-response readiness...
1 week ago
Managing Director, Assessment & Human Capital
$170K - $230K *
Drive strategic growth and innovation in AI-enabled assessment and workforce solutions. Lead high-impact projects, foster collaboration, and enhance AIR's national leadership in education and workforc...
6 days ago
$80K - $95K *
Join a team that's dedicated to driving financial excellence through detailed analysis, reporting, and strategic recommendations. Collaborate with leadership to enhance financial performance and suppo...
3 days ago
Business Resiliency Specialist III
$94K - $164K *
Drive business continuity and disaster recovery initiatives, ensuring critical operations are sustained and services restored post-disruption. Collaborate with stakeholders to assess risks, validate r...
4 days ago
$80K - $95K *
Join a team that's dedicated to matching healthcare providers with facilities, utilizing creative sourcing strategies and consultative skills to meet client needs while achieving personal productivity...
1 week ago
Manager, Executive Administration
$102K - $152K *
Transform executive support by leading a dynamic team of EAs, enhancing processes, and driving strategic initiatives that align with company goals while fostering a collaborative culture...
1 week ago
Managing Consultant, Environmental Regulatory FERC Specialist
$95K - $115K *
Drive strategic permitting initiatives for complex energy projects, ensuring compliance with FERC regulations. Leverage your expertise to influence regulatory outcomes and support sustainable energy s...
Today
$100K - $120K *
Join us to drive impactful data analysis that enhances product performance and operational effectiveness. Collaborate with cross-functional teams to uncover insights, develop KPIs, and translate compl...
3 weeks ago
Group Account Director (Medical Affairs)
$165K - $185K *
Join a team that's shaping strategic direction and driving growth across multi-account projects in medical affairs. In this senior leadership role, you'll enhance client relationships, develop teams...
Reposted 2 weeks ago
$100K - $120K *
Lead the charge in developing client relationships and driving new business opportunities in the Life Sciences sector. Utilize a consultative sales approach to create bespoke marketing campaigns and m...
4 days ago
$120K *
Join a team that's driving impactful cross-functional initiatives by leading strategic delivery efforts. Leverage your project management expertise to align complex projects with enterprise priorities...
1 week ago
$110K - $130K *
Engage in the design and management of enterprise endpoint technologies, ensuring security and efficiency across over 1,000 devices. Collaborate with cross-functional teams to enhance endpoint perform...
3 weeks ago
$88K - $105K *
Join a team that's dedicated to enhancing risk management and strengthening controls across the organization. As a Senior Internal Auditor, you'll lead audits, mentor junior staff, and influence key s...
2 weeks ago
D&T Sr Project Management Consultant - Talent Community
$110K - $130K *
Elevate your project management career by leading a strategic platform within investor client coverage, enhancing client engagement and driving technology integration across CBRE's commercial real est...
Reposted 1 week ago
Sr. Strategic Commercial Banking Consultant
$125K - $157K *
Shape the future of commercial banking by leading strategic implementations, optimizing client operations, and advising on best practices to enhance financial institution capabilities and drive long-t...
3 weeks ago
$80K - $95K *
Lead the charge in overseeing a national Audit & Compliance team, ensuring regulatory adherence, risk management, and operational excellence while driving process improvements and fostering cross-func...
1 week ago
$200K - $225K *
Transform healthcare data into actionable insights by leading actuarial strategy and health economic analyses. Collaborate with cross-functional teams to enhance value propositions and drive commercia...
Today
$95K - $115K *
Drive client success as a key Account Manager, managing relationships across diverse industries. Oversee project lifecycles, enhance client experiences, and help shape the client services function fro...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.