Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$210K - $250K *

Lead a dynamic team to drive growth and commercialization strategies, enhancing market presence and client acquisition. Collaborate cross-functionally to transform insights into actionable plans, ensu...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$175K - $215K *

Shape the future of global partnerships by leading strategic account management, driving growth, and fostering executive relationships. Oversee program success and team leadership to deliver exception...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Lead and transform regional sales strategy across Asia-Pacific, driving growth through customer engagement, team development, and market expansion. Influence commercial outcomes while fostering strong...

Yesterday

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $130K *

Lead the charge in complex H&S compliance projects while mentoring staff, managing client relationships, and ensuring the highest standards of safety and professionalism in a remote work environment...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Technical Services

$133K - $166K *

Lead the strategy and evolution of enterprise business intelligence capabilities, ensuring scalable, governed reporting and analytics. Collaborate with cross-functional teams to enhance decision-makin...

Yesterday

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Shape your career by leading a dynamic sales team, building client relationships, and implementing effective strategies. Enjoy flexibility while driving growth and providing tailored insurance solutio...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Drive new revenue growth by identifying and converting business opportunities, building executive relationships, and leading complex sales processes in a competitive landscape. Engage with customers t...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$165K - $195K *

Lead innovative solution development for Federal Government projects, translating client needs into effective strategies. Collaborate with cross-functional teams to deliver compelling proposals and en...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$165K - $195K *

Engage in strategic solution development for Federal Government initiatives, translating client needs into innovative technical strategies. Collaborate with cross-functional teams to deliver compellin...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $100K *

Transform your career with this client-facing role, leveraging your expertise in analytics tools like Google Analytics and Tag Manager to deliver strategic solutions and enhance data-driven decision-m...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Media

$120K - $155K *

Lead the charge in operational excellence for a defense technology client, driving technical hiring, change management, and safety compliance. Collaborate with cross-functional teams to ensure alignme...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $266K *

Transform mortality analytics by leading actuarial assumption modeling, translating complex insights into competitive strategies. Collaborate with cross-functional teams to enhance product offerings a...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$108K - $135K *

Champion the management of operational risks within Protection Solutions, ensuring effective identification, assessment, and mitigation. Collaborate with stakeholders to enhance risk strategies and su...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$124K - $171K *

Accelerate sales growth by managing and qualifying strategic Enterprise Intelligence opportunities. Collaborate with cross-functional teams, ensuring comprehensive engagement and communication to opti...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$120K - $150K *

Elevate your career by leading clinical trial management teams, ensuring quality and compliance in monitoring strategies. Collaborate with cross-functional teams to optimize clinical operations and dr...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $300K *

Partner with us to accelerate sales by expertly closing high-ticket B2B deals. Utilize a structured two-call system to connect with Amazon brand owners and drive significant revenue growth in a fast-p...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Pioneer a high-performing culture by partnering with leaders to deliver strategic HR solutions that enhance employee engagement, retention, and growth in a dynamic, mission-driven environment...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$94K - $148K *

Shape the future of healthcare by driving customer experience insights that influence product and business strategies. Collaborate with cross-functional teams to conduct impactful research and advocat...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Transform global operations by supporting Power Automate workflows, enhancing collaboration with regional teams, and driving continuous improvement in automation processes to optimize efficiency and e...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$116K - $165K *

Drive engineering excellence by leading the design and integration of marine vessels. Collaborate across teams to ensure compliance and quality in hull structure, propulsion, and auxiliary systems, wh...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$105K - $130K *

Lead the proposal development process, enhancing strategies and systems to elevate submissions. Collaborate with executives and technical experts to create compelling, client-focused proposals that sh...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Engage with clients to originate, underwrite, and close agricultural and business loans. Build strong relationships while ensuring compliance with lending policies and government regulations. Drive po...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$185K - $344K *

Join a dynamic team driving strategic planning and performance management across analytics capabilities. Lead portfolio governance and execution initiatives to align resources and priorities, ensuring...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the charge in global expansion strategy for an innovative English language assessment solution. Drive international partnerships, attract investors, and expand market presence across established...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$124K - $140K *

Accelerate your career by managing sales efforts for innovative products in gastroenterology. Cultivate relationships with healthcare professionals while driving business growth and addressing technic...

2 weeks ago

  •   Less than 5 years exp.  •   Staffing

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.