Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$156K - $190K *
Drive innovation as a technical leader in R&D, focusing on dental chemical consumables. Lead complex experiments, mentor junior scientists, and ensure product excellence while adhering to quality stan...
Today
Principal Scientist, Analytical Sciences
$170K - $215K *
Join our innovative R&D team to lead analytical development for therapeutics in microgravity. Drive projects from conception to regulatory filing, while mentoring junior scientists, shaping product st...
1 week ago
$111K - $120K *
Lead the charge in R&D for cutting-edge filtration technologies across diverse sectors, driving innovation in microelectronics and aerospace. Collaborate with cross-functional teams to enhance product...
Reposted 1 week ago
$80K - $95K *
Optimize E&L study execution and compliance through strategic leadership, ensuring high-quality data for regulatory submissions while mentoring teams and aligning goals with product development initia...
4 days ago
Principal Scientist - ADME - Site Based, Princeton, NJ
$113K - $154K *
Champion innovative ADME-Tox projects, collaborate with multidisciplinary teams, and lead scientific exploration while mentoring staff, driving personal growth and organizational success through effec...
Reposted yesterday
Principal Scientist - Bioseparation & Analytical Development
$120K - $150K *
Lead the charge in advancing bioseparation analytical methods for large molecules. Drive innovation in biologics characterization, supporting drug development through hands-on execution and scientific...
3 weeks ago
$100K - $130K *
Elevate your scientific career by leading innovative LCMS initiatives, defining analytical strategies, and delivering impactful results within the pharmaceutical industry while mentoring emerging scie...
Reposted yesterday
Principal Application Scientist | ELN/LUMA
$120K - $150K *
Unlock potential by leveraging deep scientific expertise and technical skills to partner with customers, ensuring the delivery of complex SaaS solutions while driving integration and data architecture...
2 weeks ago
$90K - $120K *
Innovate your career by providing analytical support for pharmaceutical development, conducting method validation, and leading studies while ensuring compliance and collaboration within a dynamic team...
2 weeks ago
$110K - $120K *
Lead innovative hair care formulation development from concept to market, utilizing advanced chemistry and collaboration across teams to overcome formulation challenges, ensure product safety, and dri...
2 weeks ago
Principal Scientist, Drug Substance Process Development & Manufacturing
$160K - $224K *
Join a team that drives Drug Substance development, overcoming complex challenges in monoclonal antibody manufacturing and scaling processes, while ensuring compliance and quality at every stage of pr...
3 weeks ago
$122K - $156K *
Join the forefront of scientific inquiry by leading impactful exposure science projects. Collaborate with diverse teams to mitigate health risks while enhancing your expertise through mentorship and c...
Reposted 6 days ago
Principal Associate Scientist, Biology
$108K - $122K *
Drive advancements in RNAi target discovery by independently executing molecular biology assays, managing cell cultures, and analyzing data to support neuroscience projects in a collaborative lab envi...
1 week ago
Principal Scientist, Analytical Development
$130K - $179K *
Unlock your potential as an analytical development lead, guiding innovative monoclonal antibody projects from preclinical to commercialization, ensuring compliance and delivering analytical excellence...
5 days ago
Senior Research Scientist, High Throughput Biology
$120K - $150K *
Take ownership of high throughput biology capabilities, designing and executing robust biochemical and cell-based assays while collaborating across teams to drive small molecule discovery and deliver...
4 weeks ago
$114K - $228K *
Drive clinical innovation by leading trial design and execution in collaboration with internal and external stakeholders to support regulatory submissions and strategic business goals within the vascu...
Reposted 2 days ago
Expert Pharma Discovery Biologist
$120K - $150K *
Lead the charge in advancing oncology through in vitro discovery biology, collaborating across programs to validate targets and drive innovative therapeutic solutions...
1 week ago
Expert Pharma Discovery Biologist
$100K - $130K *
Join a team that's pioneering in vitro discovery biology to advance oncology programs, conducting target validation and developing innovative therapies across various modalities while driving research...
1 week ago
Managing Scientist (Ph.D. or M.S.)
$131K - $161K *
Lead and oversee pre-market approval projects in food safety; provide strategic regulatory guidance, manage multi-disciplinary projects, and mentor team members in this dynamic role focused on health...
Reposted 6 days ago
Principal Computational Scientist, Discovery Chemistry
$144K - $269K *
Lead advances in peptide therapeutic discovery by developing innovative computational methods and machine learning models to optimize peptide properties and streamline workflows for drug discovery...
2 weeks ago
Principal Scientist, Process Development (Expression Systems)
$142K - $256K *
Join a team that's pioneering microbial production strategies for recombinant enzymes and plasmids, driving high-performance screening workflows, and ensuring robust process development to support inn...
2 weeks ago
Senior Principal Scientist, Pre-Formulation and Materials Science
$124K - $207K *
Drive early-stage drug design and delivery as a Senior Principal Scientist, providing leadership and scientific strategy across multi-disciplinary teams to optimize molecular and drug formulation stra...
2 weeks ago
Principal Scientist, Clinical Biomarkers
$140K - $187K *
Drive biomarker strategy for clinical studies, ensuring data quality and compliance. Collaborate across functions and external partners to enhance clinical outcomes in solid organ transplant research...
1 week ago
$130K - $150K *
Unlock potential by joining a dynamic R&D team as a Senior Scientist in DMPK. Lead drug development through strategic planning, research execution, and collaboration to drive therapies from discovery...
4 weeks ago
Senior Scientist, Computational Safety
$140K - $222K *
Lead the charge in developing advanced AI/ML models for predictive toxicity assessments. Collaborate with cross-functional teams to integrate multi-modal biological data, driving insights that improve...
2 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.