Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

$219K - $246K *

Contribute to transforming healthcare by designing AI workflows and curating unstructured data into insightful, actionable datasets, enhancing clinical decision support tools and autonomous care agent...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $175K *

Join a team that's driving innovation in diagnostic programs, leading cross-functional initiatives and ensuring operational excellence while managing high-impact projects with a focus on quality, cost...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $175K *

Shape the future of assay development by leading cross-functional teams to ensure project success through quality, efficiency, and budget adherence. Collaborate effectively while fostering team growth...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $85K *

Lead regulatory compliance and laboratory operations, ensuring quality systems integrate seamlessly with product development to foster innovation and meet industry standards. Champion a culture of saf...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $122K *

Drive innovation in advanced process controls, optimizing manufacturing through cutting-edge methodologies. Collaborate across teams to enhance control strategies, apply machine learning, and lead tec...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$79K - $209K *

Build and optimize next-gen cloud infrastructure systems while enhancing scalability and resilience through automation and innovative design solutions. Collaborate with cross-functional teams to deliv...

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $120K *

Join a team that's driving microbiology and environmental monitoring excellence to ensure product quality and compliance in a dynamic manufacturing environment while leading a skilled group of profess...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion interdisciplinary research by leading projects that explore cell biology, stress responses, and disease mechanisms for the National Heart, Lung, and Blood Institute, while fostering a collabo...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Accelerate your career as you develop and validate bioanalytical LC-MS/MS methods in a dynamic CRO environment, supporting diverse therapeutic modalities and ensuring compliance with regulatory standa...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$75K - $90K *

Elevate your career by designing and prototyping AI tools that enhance regulatory analysis. Collaborate with experts to translate complex data into actionable insights, driving efficiency in rulemakin...

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Accelerate progress at the intersection of science and law by designing impactful training programs that enhance communication skills for judicial professionals, while managing project timelines, budg...

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Join a team that's advancing small molecule discovery for Crop Health, applying your expertise in protein biochemistry and structural biology to drive scientific innovation and collaborate cross-funct...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $200K *

Unlock potential by leading piping engineering functions, ensuring compliance with industry standards, and guiding a team toward innovative solutions while delivering high-quality designs for complex...

3 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$80K - $95K *

Optimize biological feedstock transformations by leveraging lab automation for enzyme assays. Collaborate with diverse teams to enhance high-throughput screening, ensuring innovative processes are dev...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$145K - $191K *

Elevate quantum computing by developing impactful algorithms and applications. Collaborate with diverse teams and customers to solve complex real-world problems using cutting-edge trapped-ion technolo...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Join a team that's committed to innovation and quality in construction. As a Scientist, you will design, conduct tests, and develop new materials while mentoring junior chemists to drive impactful pro...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$106K - $166K *

Drive project execution by leading integrated teams, managing schedules, and ensuring stakeholder objectives are met while overseeing construction contracts and mitigating risks through effective reso...

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$66K - $124K *

Lead technical ownership and continuous improvement of energetic materials manufacturing processes, ensuring safety, efficiency, and compliance through hands-on engagement with operators and cross-fun...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $95K *

Optimize energetic material manufacturing processes with hands-on engineering support, ensuring safety and compliance. Collaborate cross-functionally to enhance productivity and drive continuous impro...

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$81K - $107K *

Engineer and optimize microbial strains for protein production in a dynamic startup. Drive DNA assembly, strain evaluation, and collaborate across teams while maintaining rigorous lab operations and d...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Elevate your career as a technical leader in pharmaceutical formulation development. Drive innovation, oversee clinical trial manufacturing, and ensure compliance, while mentoring and managing a team...

Reposted yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$173K - $204K *

Join a dynamic team to oversee API manufacturing, managing GMP and non-GMP activities, ensuring compliance and successful partnerships with CMOs for late-phase and commercial programs. Drive process i...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$121K - $171K *

Execute advanced tissue manufacturing projects, leading from concept to production ramp-up. Serve as a technical authority and mentor while collaborating cross-functionally to innovate and optimize pr...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $155K *

Develop and own precise measurement frameworks across product workflows. Collaborate with teams to establish consensus on metrics and thresholds, ensuring accountability and accuracy in live systems a...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$168K - $228K *

Champion analytical lifecycle management for commercial products globally, ensuring compliance and harmonization. Lead investigations, oversee QC networks, and drive continuous improvement while manag...

US-AnywhereRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.