Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$219K - $246K *
Contribute to transforming healthcare by designing AI workflows and curating unstructured data into insightful, actionable datasets, enhancing clinical decision support tools and autonomous care agent...
2 weeks ago
Sr. Program Manager, Clinical Chemistry & Immunoassay (Business Unit)
$160K - $175K *
Join a team that's driving innovation in diagnostic programs, leading cross-functional initiatives and ensuring operational excellence while managing high-impact projects with a focus on quality, cost...
2 weeks ago
Sr. Program Manager, Clinical Chemistry & Immunoassay (Business Unit)
$160K - $175K *
Shape the future of assay development by leading cross-functional teams to ensure project success through quality, efficiency, and budget adherence. Collaborate effectively while fostering team growth...
2 weeks ago
Compliance & Laboratory Manager
$80K - $85K *
Lead regulatory compliance and laboratory operations, ensuring quality systems integrate seamlessly with product development to foster innovation and meet industry standards. Champion a culture of saf...
4 weeks ago
Sr. Engineer, Advanced Process Controls
$88K - $122K *
Drive innovation in advanced process controls, optimizing manufacturing through cutting-edge methodologies. Collaborate across teams to enhance control strategies, apply machine learning, and lead tec...
Reposted 3 weeks ago
Senior Engineer, Core Infrastructure
$79K - $209K *
Build and optimize next-gen cloud infrastructure systems while enhancing scalability and resilience through automation and innovative design solutions. Collaborate with cross-functional teams to deliv...
6 days ago
Manager - Microbiology & Environmental Monitoring
$110K - $120K *
Join a team that's driving microbiology and environmental monitoring excellence to ensure product quality and compliance in a dynamic manufacturing environment while leading a skilled group of profess...
2 weeks ago
$110K - $130K *
Champion interdisciplinary research by leading projects that explore cell biology, stress responses, and disease mechanisms for the National Heart, Lung, and Blood Institute, while fostering a collabo...
Reposted 3 days ago
Research Scientist/Senior Scientist - LC-MS/MS
$88K - $105K *
Accelerate your career as you develop and validate bioanalytical LC-MS/MS methods in a dynamic CRO environment, supporting diverse therapeutic modalities and ensuring compliance with regulatory standa...
2 weeks ago
$75K - $90K *
Elevate your career by designing and prototyping AI tools that enhance regulatory analysis. Collaborate with experts to translate complex data into actionable insights, driving efficiency in rulemakin...
5 days ago
$95K - $115K *
Accelerate progress at the intersection of science and law by designing impactful training programs that enhance communication skills for judicial professionals, while managing project timelines, budg...
1 week ago
Research Investigator, Protein Biochemistry & Structural Biology
$95K - $115K *
Join a team that's advancing small molecule discovery for Crop Health, applying your expertise in protein biochemistry and structural biology to drive scientific innovation and collaborate cross-funct...
2 weeks ago
$130K - $200K *
Unlock potential by leading piping engineering functions, ensuring compliance with industry standards, and guiding a team toward innovative solutions while delivering high-quality designs for complex...
3 weeks ago
Scientist II - Enzyme Assay Development - Decatur, IL
$80K - $95K *
Optimize biological feedstock transformations by leveraging lab automation for enzyme assays. Collaborate with diverse teams to enhance high-throughput screening, ensuring innovative processes are dev...
6 days ago
Senior Scientist, Quantum Applications
$145K - $191K *
Elevate quantum computing by developing impactful algorithms and applications. Collaborate with diverse teams and customers to solve complex real-world problems using cutting-edge trapped-ion technolo...
Reposted 3 weeks ago
$95K - $115K *
Join a team that's committed to innovation and quality in construction. As a Scientist, you will design, conduct tests, and develop new materials while mentoring junior chemists to drive impactful pro...
Reposted 1 week ago
$106K - $166K *
Drive project execution by leading integrated teams, managing schedules, and ensuring stakeholder objectives are met while overseeing construction contracts and mitigating risks through effective reso...
1 week ago
$66K - $124K *
Lead technical ownership and continuous improvement of energetic materials manufacturing processes, ensuring safety, efficiency, and compliance through hands-on engagement with operators and cross-fun...
Reposted 1 week ago
$80K - $95K *
Optimize energetic material manufacturing processes with hands-on engineering support, ensuring safety and compliance. Collaborate cross-functionally to enhance productivity and drive continuous impro...
3 weeks ago
Senior Research Associate, Strain Engineering
$81K - $107K *
Engineer and optimize microbial strains for protein production in a dynamic startup. Drive DNA assembly, strain evaluation, and collaborate across teams while maintaining rigorous lab operations and d...
3 days ago
Pharmaceutical Development Lead Scientist I
$95K - $115K *
Elevate your career as a technical leader in pharmaceutical formulation development. Drive innovation, oversee clinical trial manufacturing, and ensure compliance, while mentoring and managing a team...
Reposted yesterday
$173K - $204K *
Join a dynamic team to oversee API manufacturing, managing GMP and non-GMP activities, ensuring compliance and successful partnerships with CMOs for late-phase and commercial programs. Drive process i...
2 weeks ago
Principal Engineer, Process Development (Lasers & Optics)
$121K - $171K *
Execute advanced tissue manufacturing projects, leading from concept to production ramp-up. Serve as a technical authority and mentor while collaborating cross-functionally to innovate and optimize pr...
Reposted 4 days ago
$130K - $155K *
Develop and own precise measurement frameworks across product workflows. Collaborate with teams to establish consensus on metrics and thresholds, ensuring accountability and accuracy in live systems a...
4 days ago
Director, Quality Analytical Technical Lead, Small Molecule
$168K - $228K *
Champion analytical lifecycle management for commercial products globally, ensuring compliance and harmonization. Lead investigations, oversee QC networks, and drive continuous improvement while manag...
4 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.