Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
$108K - $130K *
Serve as a technical leader in in vivo research, coordinating studies and mentoring staff while ensuring operational excellence and compliance within the Neurobiology group. Drive high-quality, humane...
Today
Group Leader, Analytical Characterization, Biologics
$100K - $120K *
Manage and mentor a team of junior scientists, ensuring analytical excellence and cGMP compliance in biologics product development while fostering collaboration and growth within the team...
4 weeks ago
$180K - $220K *
Transform the future of enterprise AI as you innovate rigorous research agendas, design impactful experiments, and develop systems that bridge hypotheses with production, directly influencing business...
1 week ago
$180K - $220K *
Empower enterprise innovation by leading research that transforms historical data into actionable insights, designing experiments and scalable systems for agent performance evaluation and reinforcemen...
1 week ago
$95K - $115K *
Elevate process engineering excellence by driving improvements and implementing safety measures in biomanufacturing environments. Collaborate with teams to enhance production reliability and support s...
1 week ago
Senior Product Marketing Manager
$170K - $190K *
Reimagine product marketing by transforming complex technical concepts into clear, impactful messaging that empowers diverse stakeholders. Collaborate across functions to drive engagement and showcase...
Reposted 2 weeks ago
Process Development Engineering Scientist
$104K - $156K *
Innovate and lead process development studies for cell-based drug candidates, focusing on robust cell banking and hESC expansion, while collaborating across teams to drive technical excellence and mee...
Today
Chemical Laboratory Supervisor
$88K - $105K *
Oversee laboratory operations to ensure efficient, high-quality analytical testing and support development initiatives. Manage personnel, drive continuous improvement, and implement best practices whi...
6 days ago
Federal Deputy Project Manager
$135K - $145K *
Drive the future of military facility projects by overseeing complex operations and managing multi-disciplinary teams to deliver high-quality results on time and within budget. Be the key liaison for...
1 week ago
Federal Deputy Project Manager
$135K - $145K *
Lead the charge in managing complex military facility projects, overseeing budgets, client relations, and multi-disciplinary teams to ensure successful execution of innovative solutions within stipula...
1 week ago
Federal Deputy Project Manager
$135K - $145K *
Unlock your potential as a Deputy Project Manager, leading large-scale military facility projects and collaborating with multi-disciplinary teams to ensure client satisfaction, project longevity, and...
1 week ago
Federal Deputy Project Manager
$135K - $145K *
Manage and execute large military facility projects, ensuring quality and efficiency by leading cross-functional teams and driving client satisfaction across multiple concurrent high-stakes initiative...
1 week ago
Federal Deputy Project Manager
$135K - $145K *
Partner with us to manage complex military facility projects while leading business development and data analytics initiatives. You will oversee budgets and client relationships across multi-disciplin...
1 week ago
Federal Deputy Project Manager
$135K - $145K *
Champion the management and execution of large-scale military facility projects, ensuring client satisfaction, adherence to budget and schedule while leading multidisciplinary teams to success in a co...
1 week ago
Director, New Product Planning (NPP)
$197K - $225K *
Shape commercial strategies and market positions for innovative product pipelines, collaborating with cross-functional teams to enhance asset value and drive market success through market research ins...
4 days ago
Sr Director, In Vivo Pharmacology
$215K - $235K *
Accelerate your career by leading the In Vivo/Translational Biology group, driving pharmacology projects in oncology, and shaping innovative strategies for drug candidate development from discovery to...
3 weeks ago
Regulatory Affairs Director *PC 954
$201K - $237K *
Shape regulatory strategies for CMC in cell therapy programs and collaborate across teams to ensure compliance with health authority requirements, supporting trials and product approvals throughout th...
Yesterday
Regulatory Affairs Director *PC 954
$201K - $237K *
Unlock potential by leading CMC regulatory strategies for cell therapies. Collaborate across teams to ensure compliance, prepare submissions, and drive product lifecycle success, while engaging with g...
Yesterday
Regulatory Affairs Director *PC 954
$201K - $237K *
Architect innovative regulatory strategies for CMC in cell therapy, guiding teams and leading submissions throughout product development, ensuring compliance and successful health authority interactio...
Yesterday
Regulatory Affairs Director *PC 954
$201K - $237K *
Champion regulatory CMC strategies to elevate cell and gene therapies. Drive cross-functional collaborations, oversee global submissions, and ensure compliance. Lead efforts to mitigate risks and supp...
Yesterday
Regulatory Affairs Director *PC 954
$201K - $237K *
Empower progress at the intersection of regulatory compliance and cell therapy. Lead CMC strategies for global submission readiness, partnering with cross-functional teams to navigate approvals, and e...
Yesterday
Principal Data Scientist (64_2026.3)
$200K - $215K *
Contribute to transforming consumer spend data into predictive intelligence, leading a talented team across predictive modeling and campaign measurement while ensuring standards, privacy, and methodol...
2 weeks ago
$110K - $140K *
Contribute to a seamless customer experience by connecting clients with technical and scientific operations, guiding them from initial inquiries to successful project completion in a dynamic biotechno...
3 weeks ago
Chief of Staff, Enterprise AI & Data Science
$137K - $185K *
Join us in a strategic leadership role driving operations, cross-functional alignment, and organizational effectiveness across AI & Data Science initiatives in a fast-paced environment. Make a profoun...
2 weeks ago
Research Scientist: Post-Training
$120K - $145K *
Unlock potential by training large models into production-ready robotic systems. Engage in fine-tuning, performance evaluation, and real-world implementations while becoming a full-stack ML roboticist...
1 week ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.