Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$149K - $223K *

Transform AI application engineering by owning the transition from prototype to production. Collaborate across functions to define standards, design architecture and ensure readiness within an enterpr...

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$149K - $223K *

Lead the charge in transforming AI application prototypes into robust, enterprise-ready systems. Collaborate across teams to define standards and drive innovations that ensure data integrity and acces...

Toronto, ONIn-Person

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$119K - $156K *

Join us to lead strategic sourcing for critical commodities in life sciences. You'll oversee supplier selection, cost optimization, and ensure quality while collaborating across functions to drive sup...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Empower your career by leading high-performing teams in biochemical analysis, overseeing product development under cGMP guidelines while mentoring staff and interacting with clients to ensure complian...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Pioneer advanced non-viral gene delivery technologies to enhance next-gen neurotech platforms, fostering cross-disciplinary collaboration while advancing preclinical models towards clinical translatio...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $119K *

Unlock potential by providing technical expertise and support in upstream manufacturing. Collaborate with clients, drive process improvements, and ensure effective tech transfers, while monitoring pro...

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$166K - $275K *

Engage in leading mission-critical software projects, applying AI, data analytics, and agile methodologies to drive innovative solutions, manage stakeholder expectations, and mentor teams toward opera...

3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$166K - $275K *

Manage complex software implementation projects, integrating AI and data science to deliver critical solutions. Lead multidisciplinary teams from conception to operations, ensuring alignment with miss...

3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$110K - $130K *

Drive innovation in computational chemistry to enhance agrochemical development. Collaborate with diverse teams, implement AI-driven workflows, mentor scientists, and contribute to scientific advancem...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $165K *

Lead the charge in crafting compelling technical proposals for government-funded research opportunities, collaborating with scientists and engineers to drive innovative design and implementation for s...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$113K - $277K *

Join a dynamic team to drive research and policy analysis in biosafety, biosecurity, and biotechnology governance. Leverage your expertise to inform critical decision-making and foster interdisciplina...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $170K *

Transform early cancer detection through innovative statistical analysis methods, collaborating with laboratory scientists and engineers. Drive assay development and regulatory submissions while ensur...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$259K - $380K *

Drive innovative AI initiatives in drug discovery by leading a team of experts. Define scientific direction, optimize research programs, and translate breakthroughs into practical solutions to improve...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $185K *

Empower our Custom & Bulk Services as a strategic leader driving growth, optimizing operations, and enhancing customer experience through cross-functional collaboration and effective governance in a d...

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Champion innovative technical solutions for mass transfer equipment. Collaborate across teams to ensure customer satisfaction in a fast-paced environment. Utilize your expertise to enhance operational...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Elevate manufacturing operations as you drive process improvements, enhance safety protocols, and optimize production efficiency in support of superior product quality within a collaborative environme...

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Lead the charge in optimizing glass manufacturing processes, utilizing your analytical skills and technical expertise to enhance efficiency and quality while collaborating with cross-functional teams...

4 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$174K - $252K *

Lead the charge in advancing machine learning research by developing innovative methodologies for LLMs. This role emphasizes collaboration and creativity, managing complex projects to drive breakthrou...

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Lead QC Analytical operations, ensuring compliance with best practices and regulations. Oversee a skilled team, manage testing and method validation, and collaborate across functions to ensure timely...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Transform global in vitro scientific operations by leading expansive teams and driving innovation across oncology and immunology studies. Ensure operational excellence, harmonize multi-site workflows...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive excellence in laboratory operations by leading instrument validation and method development across global QC labs, ensuring high-quality standards and compliance with regulatory requirements for...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$145K - $175K *

Accelerate the implementation of enterprise AI architecture, defining standards and governance to ensure scalable, secure AI solutions. Collaborate across teams to shape strategy and design, while men...

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$91K - $119K *

Champion process innovation by leading continuous improvement initiatives, driving Lean methodologies and Six Sigma principles to enhance operational efficiency and cultivate a culture of excellence a...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$195K - $215K *

Shape the future of defense programs by driving engineering execution, managing schedules and costs, and addressing risks. This role bridges design and program management, ensuring seamless product de...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$204K - $281K *

Unlock potential by leading biologics innovation in drug discovery, driving cross-functional programs, and mentoring a high-performing team to deliver groundbreaking biological therapies in a collabor...

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.