Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Associate Scientist, Analytical Development and Quality Control
$96K - $126K *
Join a team that's advancing nucleic acid therapeutics by optimizing analytical methods and driving sample testing efficiency, all while supporting a collaborative environment and mentoring others in...
3 days ago
Senior Scientist, Discovery Biology
$131K - $159K *
Innovate and lead research efforts in protein degradation drug discovery, leveraging expertise in cancer biology to develop targeted therapies for solid tumors. Collaborate across disciplines to enhan...
3 weeks ago
Associate Principal Scientist, Discovery Oncology, Reverse Translation
$159K - $251K *
Explore an exciting opportunity to drive innovative cancer research. Collaborate with multidisciplinary teams to identify therapeutic targets and elucidate tumor biology, enhancing our oncology pipeli...
2 weeks ago
$110K - $130K *
Empower your career by leading strategic QA initiatives that enhance software quality and user experience. Drive innovation in AI-assisted testing while collaborating across teams to maintain high org...
2 weeks ago
$185K - $190K *
Elevate progress at the forefront of electricity markets by leading innovative modeling techniques. Collaborate with engineers and product managers to create scalable solutions that shape the future o...
Reposted today
Principal Scientist, Biostatistics, Late-Stage Clinical Development
$190K - $300K *
Drive biostatistical leadership in clinical trial design, analysis, and project management, collaborating with cross-functional teams to ensure compliance with regulatory standards and improve drug an...
2 weeks ago
Principal Scientist, Biostatistics, Late-Stage Clinical Development
$190K - $300K *
Lead biostatistical initiatives in drug and vaccine projects, collaborating across teams to ensure effective trial designs and regulatory compliance. Drive statistical analysis and innovative research...
2 weeks ago
Global Head of Characterization BioAnalytics
$232K - $335K *
Execute a global strategy for analytical characterization of biologics, leading a multi-site organization and ensuring high-quality deliverables while driving talent development and innovative analyti...
2 weeks ago
Senior Principal Applied Scientist
$197K - $267K *
Lead the charge in applied machine learning, guiding scientific direction and transforming research into impactful production models while mentoring a dynamic team to meet evolving AI challenges...
1 week ago
$79K - $131K *
Optimize procurement strategies by leading complex sourcing initiatives and supplier management efforts. Mentor junior staff while collaborating with cross-functional teams to enhance operational effi...
Reposted 3 weeks ago
Visiting Scientist Fellow - Regulatory (FDE)
$86K *
Reimagine your future in the pharmaceutical industry through hands-on experience in regulatory policy and strategic areas, collaborating across departments to impact drug development and health outcom...
Yesterday
$110K - $130K *
Advance your career by managing complex pharmaceutical projects, ensuring alignment with regulatory standards and delivering quality outcomes while leading cross-functional teams to drive project succ...
4 weeks ago
$90K - $110K *
Join a team that's driving innovation in oncology by managing projects to advance approved imaging agents and late-stage products, enhancing lives through strategic planning, execution, and collaborat...
Reposted today
Senior Scientist I/II, Process Engineering
$110K - $130K *
Unlock potential by joining our Process Engineering team to develop robust processes for small and large molecule drug production, focusing on crystallization and innovative technologies throughout pr...
3 weeks ago
$159K - $183K *
Optimize operational functions by collaborating with teams to streamline processes, manage vendor relationships, and tackle unique challenges while supporting the CEO. Drive growth by owning recruitme...
1 week ago
Senior Food Scientist, Protein
$95K - $115K *
Lead the charge in fresh beef product innovation by providing technical expertise and developing innovative solutions that enhance manufacturing processes and strengthen client relationships across No...
1 week ago
$142K - $235K *
Lead the simulation engineering team to develop and integrate advanced simulation models, ensuring timely delivery of cutting-edge capabilities for space exploration. Engage in hands-on technical work...
1 week ago
$186K - $233K *
Build your expertise in pharmacovigilance as you provide safety science support across products. Develop risk management strategies, ensure compliance, and collaborate with cross-functional teams to e...
6 days ago
$110K - $130K *
Lead cross-functional teams to drive product development and engineering projects in the medical device industry. Ensure successful project execution from concept to commercialization while aligning w...
4 weeks ago
Scientist II, Automated Strain Engineering
$105K - $168K *
Join a team that's innovating high-throughput cloning and yeast strain construction. As a Scientist II, you'll develop methods that enhance efficiency, mentor junior researchers, and lead automation e...
4 days ago
Principal Scientist, AI & Autonomous Discovery Systems - Spring House, PA
$117K - $201K *
Join a team that's pioneering AI-driven drug discovery, transforming scientific decision-making and accelerating therapeutic advancements through innovative autonomous systems and intelligent research...
3 weeks ago
Principal Scientist, AI & Autonomous Discovery Systems - Spring House, PA
$117K - $201K *
Champion AI-powered drug discovery, shaping autonomous systems that enhance laboratory workflows and foster innovative research across therapeutic areas to accelerate the development of revolutionary...
3 weeks ago
Scientific Director, Pathology
$177K - $278K *
Champion innovative AI/ML pathology integration into nonclinical research workflows, providing scientific leadership and collaborating with global project teams to drive program excellence and decisio...
3 weeks ago
Senior Scientist, Statistical Programming
$117K - $184K *
Join a team that's driving advances in statistical programming for late-stage drug development. Take ownership of critical analysis projects, collaborating across departments to ensure high-quality de...
3 weeks ago
$100K - $120K *
Join a team that's managing geological risks and optimizing mine performance while leading skilled geologists. Contribute to resource modelling and continuous improvement in a collaborative mining env...
Reposted yesterday
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.