Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$275K - $310K *

Shape the future of cancer screening as you lead assay development for innovative IVD products, guiding your team through scientific challenges and regulatory complexities to deliver high-quality solu...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Join a team that's dedicated to enhancing homeland security by providing expert analysis on CBRN threats, driving innovative solutions, and collaborating with diverse professionals to protect public h...

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$125K - $150K *

Pioneer HR solutions by partnering with site leaders to enhance talent management, foster inclusive culture, and ensure compliance. Drive initiatives that optimize performance, coaching front-line and...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$99K - $149K *

Grow your expertise in drug product development by engaging with innovative analytical techniques and collaborating across teams, driving excellence in formulation development and real-time process an...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Serve as a key leader in managing complex environmental projects, ensuring compliance and client satisfaction. Leverage your expertise to drive project execution, develop proposals, and guide a team i...

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$90K - $110K *

Shape the future of mechanical engineering by leading the design, testing, and support of sealed sources and transport packages in the nuclear industry. Engage with cross-functional teams to innovate...

Ottawa, ONIn-Person

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$90K - $120K *

Lead the charge in advanced geophysical studies for transportation infrastructure, overseeing teams and subcontractors. Integrate GIS/BIM models to enhance design value, ensuring compliance and foster...

US-AnywhereIn-Person

Reposted 6 days ago

  •   11 - 15 years exp.  •   Transportation

$186K - $233K *

Transform research workflows and decisions by empowering Biology teams with AI-enabled products. Drive product strategy, enhance data capabilities, and enable self-service analytics to accelerate insi...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Join a team that's spearheading advanced geophysical studies to enhance infrastructure design, leading multidisciplinary campaigns, and mentoring a dedicated team while integrating cutting-edge data m...

Montreal, QCIn-Person

Reposted 6 days ago

  •   11 - 15 years exp.  •   Transportation

$75K - $95K *

Take ownership of the technical direction and delivery of studies, ensuring compliance and timely completion. Engage with clients and guide project management while maintaining high scientific and reg...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $110K *

Elevate your career by ensuring project delivery and regulatory compliance, while fostering customer relationships and overseeing technical testing processes in a dynamic laboratory environment...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$219K - $305K *

Shape the future of responsible AI by driving strategic initiatives that enhance user safety. Collaborate with global teams to tackle critical trust and safety challenges, ensuring alignment and commu...

1 week ago

  •   11 - 15 years exp.  •   Consumer Technology

$164K - $205K *

Execute quality assurance strategies for commercial batch review and product release, ensuring regulatory compliance and timely distribution. Collaborate with cross-functional teams to maintain supply...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$164K - $205K *

Help us optimize GMP Quality Assurance processes for our clinical programs. Lead batch review, product release activities, and compliance efforts while collaborating with cross-functional teams to sup...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$250K - $300K *

Explore cutting-edge AI research at the intersection of agentic systems and execution environments. Lead innovation in scalable applications and influence product direction by translating advanced met...

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$70K - $95K *

Elevate your career by executing bio-analytical method qualifications and data analysis in a dynamic team. Collaborate on cutting-edge projects, employing technical expertise to drive innovation and e...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$250K - $300K *

Transform the future of AI systems by defining research strategies, driving innovations, and ensuring reliable production deployments in regulated environments. Your expertise will lead to the evoluti...

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$250K - $300K *

Transform AI research by leading innovations in autonomous systems and agentic infrastructure, ensuring safe and effective deployment in regulated environments. Drive strategic direction through exper...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$80K - $110K *

Transform project execution by applying advanced controls engineering skills to optimize biomanufacturing projects. Collaborate with diverse teams to enhance client relationships and drive performance...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$75K - $95K *

Lead and ensure the effectiveness of laboratory activities in construction materials, delivering high-quality testing services while prioritizing safety, training, and compliance with quality standard...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$75K - $95K *

Lead a team focused on coordinating lab operations for construction and geotechnical materials. Ensure testing quality, personnel safety, and compliance with project requirements while promoting a cul...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $130K *

Transform environmental projects by championing safety, leading complex investigations, and driving innovative solutions through collaboration. Utilize expertise in geology to interpret subsurface dat...

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$100K - $130K *

Elevate environmental assessments by interpreting subsurface data, leading complex projects, and ensuring safety and quality standards while mentoring junior staff to enhance their technical skills an...

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$175K - $230K *

Empower quality assurance by ensuring compliance with regulations and driving continuous improvement. This role involves cross-functional collaboration and technical expertise to enhance operational e...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$70K - $95K *

Inspire innovation in laboratory practices as you lead method development and validation in a dynamic Chemistry Lab environment, ensuring quality and analytical excellence in compliance with ISO stand...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.