Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$126K - $159K *

Drive innovative chemoproteomics workflows, collaborating with cross-functional teams to support drug discovery and platform advancements in a fast-paced research environment, leveraging mass spectrom...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $222K *

Join a team that's driving innovation in drug development by designing and executing advanced assays to evaluate immunogenicity, while mentoring staff and enhancing R&D initiatives in a collaborative...

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Contribute to scientific excellence by leading advanced research initiatives aimed at integrating emerging technologies, mentoring top talent, and advancing sustainable practices in biomedical researc...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead and empower global production operations through immersive training in China before transitioning to a senior role abroad, shaping future biopharmaceutical leadership with a blend of local insigh...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Accelerate progress at a global scale by leading upstream production initiatives. Develop talent and optimize processes through deep immersion in local systems for impactful project delivery and cross...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$300K - $320K *

Explore the intersection of AI and biology, driving advancements in computational biology and empowering scientific workflows through innovative tools and model capabilities that bridge biology and ma...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$99K - $120K *

Reimagine research excellence as a Senior Scientist II, driving projects in PhysChem to advance technologies, support market innovations, and collaborate across teams, while leading junior researchers...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$161K - $185K *

Grow your career with our team as a Senior Scientist in Analytical Development. Leverage your expertise in drug product analytical methods, supporting regulatory submissions and guiding cross-function...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$71K - $187K *

Advance your career by leading innovative oncology research initiatives. Design and execute in vitro studies, develop bioanalytical methods, and collaborate cross-functionally to drive drug discovery...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Join our team to lead the development of innovative cellular assays in immunology, drive cross-functional collaborations, and integrate cutting-edge AI/ML methods for drug discovery projects aiming to...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Innovate with us in developing transformative therapies by leading drug discovery projects in immunology. Collaborate with multidisciplinary teams to progress from target identification to clinical de...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$71K - $187K *

Engage with a dynamic team to engineer, characterize, and optimize biotherapeutics, focusing on antibody development. Collaborate across disciplines to drive innovation and improve therapeutic outcome...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$172K - $221K *

Join a team that's at the leading edge of structural biology, driving innovative drug discovery. Lead protein biochemistry efforts, mentor talent, and collaborate across functions to unlock new insigh...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $118K *

Join a team that's at the forefront of high-throughput Chemistry innovation, driving hands-on experimentation and automation. Contribute to critical projects using advanced technologies to impact scie...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$113K - $165K *

Transform innovative ideas into practical ML and AI applications by collaborating with multi-disciplinary teams to develop state-of-the-art solutions and prototypes for diverse projects in autonomous...

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$123K - $187K *

Champion the development of innovative assay workflows for nanopore sequencing, translating bench methods into automated protocols. Collaborate cross-functionally to optimize and validate processes, d...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$248K - $360K *

Champion innovative engineering solutions by leading the architecture and development of cutting-edge AI-native products, while transforming workflows through AI tools and driving scalable, high-quali...

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$248K - $360K *

Join a team that's reshaping AI engineering by defining scalable architectures and fostering innovative practices that integrate generative models and AI tools in the development workflow for cutting...

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$190K - $360K *

Innovate in AI-driven engineering as a Principal Scientist, shaping architectures and enhancing developer experiences across diverse platforms. Collaborate with cross-functional teams, adopting best p...

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$190K - $360K *

Elevate the future of AI engineering by guiding architectural innovation and hands-on implementation for a transformative AI-native product. Collaborate across teams to define technical strategies and...

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$173K - $272K *

Elevate your career by leading the development of innovative upstream processes for biotherapeutics, guiding technical strategies, fostering collaboration, and mentoring junior scientists in a fast-pa...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$126K - $140K *

Partner with us to advance biotherapeutics by developing and qualifying potency assays, driving analytical strategies, and mentoring junior scientists in a collaborative, innovative environment...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Transform drug discovery processes by leveraging advanced computational chemistry techniques. Collaborate with scientists to synthesize innovative compounds and develop workflows that prioritize compo...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$173K - $272K *

Grow your career with an opportunity to lead cross-functional teams in developing innovative CMC strategies for biologic processes, ensuring successful progression from early to late-stage clinical de...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$93K - $156K *

Lead the charge in enhancing early drug delivery strategies by leveraging expertise in pharmaceutical sciences. Collaborate with cross-functional teams to evaluate drug candidates and design formulati...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.